Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 929832..930499 Replicon plasmid pRetNXC12e
Accession NZ_CP020911
Organism Rhizobium etli strain NXC12

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NXC12_RS32660 Protein ID WP_086084463.1
Coordinates 930056..930499 (+) Length 148 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NXC12_RS32655 Protein ID WP_086084548.1
Coordinates 929832..930059 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXC12_RS32635 925369..926775 - 1407 WP_086084460.1 aldehyde dehydrogenase family protein -
NXC12_RS32640 926878..927864 - 987 WP_086084461.1 helix-turn-helix domain-containing protein -
NXC12_RS32645 927956..928459 - 504 WP_086084462.1 homoprotocatechuate degradation operon regulator HpaR -
NXC12_RS32650 928809..929572 + 764 WP_157700482.1 IS5 family transposase -
NXC12_RS32655 929832..930059 + 228 WP_086084548.1 CopG family transcriptional regulator Antitoxin
NXC12_RS32660 930056..930499 + 444 WP_086084463.1 PIN domain-containing protein Toxin
NXC12_RS33385 930858..931148 - 291 WP_157700483.1 hypothetical protein -
NXC12_RS33390 931281..931391 - 111 Protein_866 IS630 family transposase -
NXC12_RS32670 931397..931621 + 225 WP_086084465.1 hypothetical protein -
NXC12_RS32675 932300..934078 + 1779 WP_086084466.1 hypothetical protein -
NXC12_RS32680 934210..935397 - 1188 WP_086084467.1 amidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - htpB 1..978479 978479


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(2-131)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 148 a.a.        Molecular weight: 15589.80 Da        Isoelectric Point: 6.7532

>T75680 WP_086084463.1 NZ_CP020911:930056-930499 [Rhizobium etli]
VTFLLDVNVLIALIDPGHVAHDDAHEWFAAMGQTAWATCPITENGVIRIVGNPKYPNSPGSPSLVMEIVRKLRSLPGHSF
WPDDVSLVGSGDIDPTRILTPGQVTDTYLLALAKAHGGRLATFDRKLSAAAVTRGNSALHLITASGS

Download         Length: 444 bp

>T75680 NZ_CP020911:930056-930499 [Rhizobium etli]
GTGACCTTCCTGCTCGACGTCAATGTGCTGATTGCCTTGATCGATCCGGGTCATGTAGCCCATGATGATGCGCACGAGTG
GTTTGCGGCGATGGGTCAGACCGCTTGGGCTACCTGCCCCATTACCGAAAATGGTGTCATCCGGATTGTCGGCAACCCCA
AATATCCCAACTCTCCCGGCTCACCGTCACTCGTGATGGAGATCGTCCGCAAATTGCGGTCGCTCCCCGGTCACAGTTTT
TGGCCGGACGATGTGAGCCTTGTCGGTTCAGGTGATATCGATCCTACGAGAATCCTAACACCGGGCCAGGTGACTGACAC
CTATCTGCTTGCACTAGCTAAAGCGCATGGGGGCCGGCTGGCGACATTCGATCGCAAGCTGTCAGCAGCAGCGGTTACAA
GGGGCAATTCTGCCTTGCACCTGATCACCGCGAGTGGATCGTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8154.36 Da        Isoelectric Point: 7.0120

>AT75680 WP_086084548.1 NZ_CP020911:929832-930059 [Rhizobium etli]
MRTTLAIDDDVLIAAKAMATQQHRSVGEVISELARRSLRRPPSSGERNGIPLLSARPDAPPVTLEIVNALRDELP

Download         Length: 228 bp

>AT75680 NZ_CP020911:929832-930059 [Rhizobium etli]
ATGAGAACGACCTTGGCAATTGACGACGATGTCCTGATCGCCGCAAAAGCGATGGCAACCCAGCAGCACCGGAGCGTCGG
CGAAGTCATTTCTGAGCTGGCGAGACGTTCTCTGCGCCGACCGCCCAGCAGCGGCGAGCGCAATGGCATTCCTCTCCTGT
CAGCTCGGCCGGATGCGCCGCCAGTGACGCTCGAAATCGTGAACGCCTTGCGTGACGAACTGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References