Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapC-vagC/VapC-VagC
Location 290291..290928 Replicon plasmid pRetNXC12e
Accession NZ_CP020911
Organism Rhizobium etli strain NXC12

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NXC12_RS29630 Protein ID WP_086084182.1
Coordinates 290291..290692 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag NXC12_RS29635 Protein ID WP_086084183.1
Coordinates 290692..290928 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXC12_RS29595 286896..287308 - 413 Protein_262 hypothetical protein -
NXC12_RS29600 287305..287574 - 270 WP_086084178.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
NXC12_RS29605 287752..288222 - 471 WP_086084179.1 hypothetical protein -
NXC12_RS33705 288556..288723 - 168 WP_016735266.1 hypothetical protein -
NXC12_RS29620 289038..289361 - 324 WP_008530485.1 DUF736 family protein -
NXC12_RS29625 289824..290156 + 333 WP_198388454.1 WGR domain-containing protein -
NXC12_RS29630 290291..290692 - 402 WP_086084182.1 type II toxin-antitoxin system VapC family toxin Toxin
NXC12_RS29635 290692..290928 - 237 WP_086084183.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
NXC12_RS29640 291516..292724 + 1209 WP_086084184.1 DUF1173 domain-containing protein -
NXC12_RS29645 292877..293908 - 1032 WP_086084185.1 P-type DNA transfer ATPase VirB11 -
NXC12_RS29650 293917..295092 - 1176 WP_086084186.1 type IV secretion system protein VirB10 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - htpB 1..978479 978479


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-117)

Antitoxin

SpoVT-AbrB domain

(7-46)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14924.20 Da        Isoelectric Point: 4.9309

>T75679 WP_086084182.1 NZ_CP020911:c290692-290291 [Rhizobium etli]
MPLYMLDTNMCIYLMKEQPPQVARRFAECRVGDVVLSAITFAELEYGVSATANAEKERANLEFLIEAIPVAPFDANAARA
YGSVRFATRERKKDHLDKLIAAHALSIDAVLVTNNMRDFSVYEGLPIENWLLS

Download         Length: 402 bp

>T75679 NZ_CP020911:c290692-290291 [Rhizobium etli]
ATGCCGCTTTATATGCTCGACACGAACATGTGTATCTACCTGATGAAGGAGCAGCCGCCGCAAGTCGCGCGCCGCTTTGC
TGAATGCCGCGTCGGTGACGTTGTCTTGTCAGCCATTACATTTGCTGAACTTGAATATGGTGTCTCTGCCACGGCGAACG
CGGAAAAGGAGCGGGCAAACCTGGAATTCCTGATAGAGGCGATTCCAGTTGCGCCCTTCGACGCCAATGCGGCGCGGGCC
TACGGGTCCGTCAGATTTGCCACGCGCGAACGGAAAAAAGACCATCTGGACAAATTGATAGCCGCTCATGCGCTCTCGAT
TGATGCGGTCCTCGTGACCAACAATATGCGGGACTTTTCTGTCTATGAAGGGTTGCCGATTGAGAACTGGTTGTTGTCGT
GA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8908.00 Da        Isoelectric Point: 5.1299

>AT75679 WP_086084183.1 NZ_CP020911:c290928-290692 [Rhizobium etli]
VHTTKVFKNGNSQAVRIPADLAYSQTEMDLEIERIGDEIRIRPLKPSLEGVLSRFARFDRSFMAEGRGDQEQTERDAL

Download         Length: 237 bp

>AT75679 NZ_CP020911:c290928-290692 [Rhizobium etli]
GTGCACACGACCAAGGTATTCAAAAACGGCAACTCACAAGCTGTGCGCATCCCTGCGGATTTGGCTTACAGCCAGACCGA
GATGGACCTTGAAATCGAGCGAATCGGTGACGAGATTCGCATACGCCCGCTGAAGCCGTCCCTGGAAGGCGTGCTTTCGC
GTTTCGCAAGGTTTGACCGCTCGTTCATGGCAGAAGGACGCGGTGATCAGGAGCAGACCGAGCGGGATGCGCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References