Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 164649..165439 Replicon plasmid pRetNXC12e
Accession NZ_CP020911
Organism Rhizobium etli strain NXC12

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag NXC12_RS29020 Protein ID WP_086084113.1
Coordinates 164942..165439 (+) Length 166 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag NXC12_RS29015 Protein ID WP_086084112.1
Coordinates 164649..164945 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXC12_RS28985 160796..161263 + 468 WP_086084110.1 DUF2269 domain-containing protein -
NXC12_RS28990 161663..161923 + 261 WP_041679349.1 DUF982 domain-containing protein -
NXC12_RS28995 161920..162138 + 219 WP_016736089.1 hypothetical protein -
NXC12_RS29000 162451..163356 + 906 WP_086084111.1 NAD(P)/FAD-dependent oxidoreductase -
NXC12_RS29005 163552..164100 + 549 WP_011428446.1 DUF1003 domain-containing protein -
NXC12_RS29010 164140..164376 + 237 WP_198388451.1 hypothetical protein -
NXC12_RS29015 164649..164945 + 297 WP_086084112.1 DUF1778 domain-containing protein Antitoxin
NXC12_RS29020 164942..165439 + 498 WP_086084113.1 GNAT family N-acetyltransferase Toxin
NXC12_RS29030 166304..167242 + 939 WP_086084114.1 hypothetical protein -
NXC12_RS29035 167615..169237 + 1623 WP_086084115.1 EAL domain-containing protein -
NXC12_RS29040 169395..170012 - 618 WP_086084116.1 exopolysaccharide biosynthesis protein -
NXC12_RS29045 170009..170317 - 309 WP_086084117.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - htpB 1..978479 978479


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(35-142)

Antitoxin

Vibrio phage ICP1, Orf50

(10-97)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 17785.24 Da        Isoelectric Point: 6.8728

>T75678 WP_086084113.1 NZ_CP020911:164942-165439 [Rhizobium etli]
VTLSAPAPLAEHHELAEFNSGVGELDDWLRRRARSNQTSGASRTFVVCEESRVIAYYALASGAVRQPEAPGRFRRNMPEP
ISVAVLGRLAIDQSYQGRGIGSALVRDAGLRLLNAAEVLGIRGMLVHAISDDARAFYEAAGFLSSPSDPMMLMVGLHDLN
KALNP

Download         Length: 498 bp

>T75678 NZ_CP020911:164942-165439 [Rhizobium etli]
GTGACCCTCAGCGCACCGGCACCCCTGGCCGAACATCATGAGCTGGCCGAGTTCAATTCCGGAGTCGGGGAACTTGACGA
CTGGCTGCGACGTCGCGCCCGTTCTAATCAGACAAGCGGCGCATCGCGGACCTTCGTCGTGTGCGAGGAGAGCCGCGTCA
TCGCCTATTACGCGCTCGCTTCCGGCGCCGTCAGACAGCCGGAAGCACCTGGCCGCTTTCGGCGCAATATGCCTGAACCA
ATTTCGGTCGCTGTTCTCGGTCGCCTCGCCATTGATCAATCCTACCAAGGGCGCGGTATCGGCAGCGCATTGGTGCGCGA
CGCGGGCCTGCGCCTGCTCAATGCCGCTGAAGTGCTTGGCATTCGAGGTATGCTCGTTCATGCGATTTCAGATGACGCAC
GAGCCTTCTACGAGGCCGCCGGCTTCCTGTCTTCTCCCTCAGACCCCATGATGCTGATGGTCGGATTGCATGACCTCAAT
AAGGCGCTGAACCCTTAG

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11119.61 Da        Isoelectric Point: 5.8769

>AT75678 WP_086084112.1 NZ_CP020911:164649-164945 [Rhizobium etli]
MPTSHTSKSSDPSVPLNMRIKPATRNLIDRAAELLGKTRTDFMLEASERRAEEVLLDRTIFTVSPEIYAEYLTRLDAPTQ
PNERLARTMSTKAPWDEA

Download         Length: 297 bp

>AT75678 NZ_CP020911:164649-164945 [Rhizobium etli]
ATGCCGACCTCACACACGAGCAAGAGCTCGGACCCAAGCGTCCCGCTAAATATGCGCATCAAGCCTGCAACCCGCAATCT
GATCGATCGAGCCGCTGAGTTGCTTGGTAAGACGCGAACGGATTTCATGTTGGAAGCTTCCGAGCGCCGAGCCGAGGAAG
TGCTGCTCGACCGCACTATCTTCACGGTAAGCCCGGAAATCTATGCGGAATACCTTACTCGGCTCGATGCACCCACGCAG
CCCAATGAGCGTCTAGCACGCACCATGTCGACCAAGGCACCGTGGGATGAGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References