Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 1696634..1697228 Replicon chromosome
Accession NZ_CP020906
Organism Rhizobium etli strain NXC12

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NXC12_RS08460 Protein ID WP_042118257.1
Coordinates 1696634..1697023 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NXC12_RS08465 Protein ID WP_080655789.1
Coordinates 1697007..1697228 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXC12_RS08440 1691876..1692496 - 621 WP_011424955.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -
NXC12_RS08445 1692543..1693832 - 1290 WP_086082005.1 dihydroorotase -
NXC12_RS08450 1693829..1694785 - 957 WP_011424957.1 aspartate carbamoyltransferase catalytic subunit -
NXC12_RS08455 1694964..1696622 + 1659 WP_020921029.1 acyl-CoA dehydrogenase family protein -
NXC12_RS08460 1696634..1697023 - 390 WP_042118257.1 PIN domain nuclease Toxin
NXC12_RS08465 1697007..1697228 - 222 WP_080655789.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NXC12_RS08470 1697375..1700260 - 2886 WP_086082006.1 Rne/Rng family ribonuclease -
NXC12_RS08475 1700883..1702142 + 1260 WP_086082007.1 N-acetylmuramoyl-L-alanine amidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-120)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14719.02 Da        Isoelectric Point: 6.6425

>T75676 WP_042118257.1 NZ_CP020906:c1697023-1696634 [Rhizobium etli]
VIVVDSSVWIAHLRGIENAARRRLQNIEDPLEILVGDLILMEVLQGARDDRHATTIEANLRQFTIRPMLDDSLAVRAARN
YRLLRERGITMRKTIDVIIGTFCIQEGHSLLHDDRDFDPMAQHLGLKIA

Download         Length: 390 bp

>T75676 NZ_CP020906:c1697023-1696634 [Rhizobium etli]
GTGATCGTCGTCGATAGTTCGGTCTGGATTGCGCATCTACGTGGGATAGAAAACGCCGCTAGACGGCGTCTGCAGAATAT
CGAAGATCCGCTGGAGATTCTTGTTGGCGATCTTATTCTTATGGAGGTCCTCCAAGGCGCGCGCGATGACCGTCATGCAA
CCACCATCGAAGCGAATTTGCGCCAATTCACGATCCGTCCGATGCTTGACGACAGCCTCGCCGTTAGGGCAGCCCGCAAT
TATCGCCTGCTGCGGGAACGCGGTATCACAATGCGCAAGACCATCGACGTAATCATTGGCACATTCTGCATTCAAGAAGG
CCACTCGCTCTTGCACGATGATAGGGATTTCGATCCCATGGCCCAGCATCTCGGTCTCAAGATCGCCTGA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8171.25 Da        Isoelectric Point: 10.9254

>AT75676 WP_080655789.1 NZ_CP020906:c1697228-1697007 [Rhizobium etli]
MRTNIDIDDALLHAAMTATGLATKKATIEQALRSLVDRHRRKNAIANLSGIGWEGDLEGMRRDRPEGTSDRRR

Download         Length: 222 bp

>AT75676 NZ_CP020906:c1697228-1697007 [Rhizobium etli]
ATGCGGACGAATATAGATATCGATGATGCCTTGCTCCACGCAGCGATGACCGCCACGGGGTTGGCGACGAAAAAAGCTAC
CATTGAACAGGCCCTCCGAAGCCTCGTCGACAGGCACCGCAGAAAAAATGCGATCGCAAATCTCTCTGGAATCGGCTGGG
AGGGTGATCTGGAAGGGATGCGCCGCGATCGACCGGAAGGAACCAGTGATCGTCGTCGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References