Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 1696634..1697228 Replicon chromosome
Accession NZ_CP020906
Organism Rhizobium etli strain NXC12

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NXC12_RS08460 Protein ID WP_042118257.1
Coordinates 1696634..1697023 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NXC12_RS08465 Protein ID WP_080655789.1
Coordinates 1697007..1697228 (-) Length 74 a.a.

Genomic Context

NXC12_RS08455NXC12_RS08475NXC12_RS08440NXC12_RS08445NXC12_RS08450NXC12_RS08460NXC12_RS08465NXC12_RS08470
Location: 1694964..1696622 (1659 bp)
Type: Others
Protein ID: WP_020921029.1
Location: 1700883..1702142 (1260 bp)
Type: Others
Protein ID: WP_086082007.1
Location: 1691876..1692496 (621 bp)
Type: Others
Protein ID: WP_011424955.1
Location: 1692543..1693832 (1290 bp)
Type: Others
Protein ID: WP_086082005.1
Location: 1693829..1694785 (957 bp)
Type: Others
Protein ID: WP_011424957.1
Location: 1696634..1697023 (390 bp)
Type: Toxin
Protein ID: WP_042118257.1
Location: 1697007..1697228 (222 bp)
Type: Antitoxin
Protein ID: WP_080655789.1
Location: 1697375..1700260 (2886 bp)
Type: Others
Protein ID: WP_086082006.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NXC12_RS084401691876..1692496-621WP_011424955.1glycerol-3-phosphate 1-O-acyltransferase PlsY-
NXC12_RS084451692543..1693832-1290WP_086082005.1dihydroorotase-
NXC12_RS084501693829..1694785-957WP_011424957.1aspartate carbamoyltransferase catalytic subunit-
NXC12_RS084551694964..1696622+1659WP_020921029.1acyl-CoA dehydrogenase family protein-
NXC12_RS084601696634..1697023-390WP_042118257.1PIN domain nucleaseToxin
NXC12_RS084651697007..1697228-222WP_080655789.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
NXC12_RS084701697375..1700260-2886WP_086082006.1Rne/Rng family ribonuclease-
NXC12_RS084751700883..1702142+1260WP_086082007.1N-acetylmuramoyl-L-alanine amidase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-120)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14719.02 Da        Isoelectric Point: 6.6425

>T75676 WP_042118257.1 NZ_CP020906:c1697023-1696634 [Rhizobium etli]
VIVVDSSVWIAHLRGIENAARRRLQNIEDPLEILVGDLILMEVLQGARDDRHATTIEANLRQFTIRPMLDDSLAVRAARN
YRLLRERGITMRKTIDVIIGTFCIQEGHSLLHDDRDFDPMAQHLGLKIA

Download         Length: 390 bp

>T75676 NZ_CP020906:c1697023-1696634 [Rhizobium etli]
GTGATCGTCGTCGATAGTTCGGTCTGGATTGCGCATCTACGTGGGATAGAAAACGCCGCTAGACGGCGTCTGCAGAATAT
CGAAGATCCGCTGGAGATTCTTGTTGGCGATCTTATTCTTATGGAGGTCCTCCAAGGCGCGCGCGATGACCGTCATGCAA
CCACCATCGAAGCGAATTTGCGCCAATTCACGATCCGTCCGATGCTTGACGACAGCCTCGCCGTTAGGGCAGCCCGCAAT
TATCGCCTGCTGCGGGAACGCGGTATCACAATGCGCAAGACCATCGACGTAATCATTGGCACATTCTGCATTCAAGAAGG
CCACTCGCTCTTGCACGATGATAGGGATTTCGATCCCATGGCCCAGCATCTCGGTCTCAAGATCGCCTGA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8171.25 Da        Isoelectric Point: 10.9254

>AT75676 WP_080655789.1 NZ_CP020906:c1697228-1697007 [Rhizobium etli]
MRTNIDIDDALLHAAMTATGLATKKATIEQALRSLVDRHRRKNAIANLSGIGWEGDLEGMRRDRPEGTSDRRR

Download         Length: 222 bp

>AT75676 NZ_CP020906:c1697228-1697007 [Rhizobium etli]
ATGCGGACGAATATAGATATCGATGATGCCTTGCTCCACGCAGCGATGACCGCCACGGGGTTGGCGACGAAAAAAGCTAC
CATTGAACAGGCCCTCCGAAGCCTCGTCGACAGGCACCGCAGAAAAAATGCGATCGCAAATCTCTCTGGAATCGGCTGGG
AGGGTGATCTGGAAGGGATGCGCCGCGATCGACCGGAAGGAACCAGTGATCGTCGTCGATAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References