Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1093674..1093818 Replicon chromosome
Accession NZ_CP020901
Organism Klebsiella pneumoniae strain K66-45

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1093710..1093812 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1093674..1093818 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B5G58_RS05165 1088804..1090864 + 2061 WP_004151449.1 oligopeptidase B -
B5G58_RS05170 1090868..1091527 - 660 WP_002911407.1 exodeoxyribonuclease X -
B5G58_RS05175 1091606..1091836 - 231 WP_002911406.1 DNA polymerase III subunit theta -
B5G58_RS05180 1091949..1092323 + 375 WP_004151448.1 CopC domain-containing protein YobA -
B5G58_RS05185 1092327..1093196 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
B5G58_RS05190 1093213..1093551 + 339 WP_002911404.1 YebY family protein -
- 1093674..1093818 - 145 - - Antitoxin
- 1093710..1093812 + 103 - - Toxin
B5G58_RS05195 1093945..1094304 - 360 WP_077253379.1 tyrosine-type recombinase/integrase -
B5G58_RS31170 1094303..1094782 + 480 WP_032419797.1 lysis protein -
B5G58_RS05210 1095571..1097076 + 1506 WP_060544606.1 hypothetical protein -
B5G58_RS05215 1097326..1097754 - 429 WP_032419788.1 type II toxin-antitoxin system PemK/MazF family toxin -
B5G58_RS05220 1097764..1098045 - 282 WP_032419786.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T75651 NZ_CP020901:1093710-1093812 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT75651 NZ_CP020901:c1093818-1093674 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References