Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3479431..3480887 Replicon chromosome
Accession NZ_CP020894
Organism Legionella longbeachae strain F1157CHC

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag B0B39_RS15445 Protein ID WP_085662656.1
Coordinates 3479431..3480282 (-) Length 284 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag B0B39_RS15450 Protein ID WP_059428262.1
Coordinates 3480279..3480887 (-) Length 203 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B0B39_RS15420 3475041..3475394 - 354 WP_085662654.1 conjugal transfer transcriptional regulator TraJ -
B0B39_RS15425 3475788..3476132 + 345 WP_012979422.1 TraK family protein -
B0B39_RS15430 3476132..3476857 + 726 WP_012979423.1 conjugal transfer protein TraL -
B0B39_RS15435 3476857..3477294 + 438 WP_012979424.1 conjugal transfer protein TraM -
B0B39_RS15440 3477442..3479349 + 1908 WP_105223259.1 DUF2779 domain-containing protein -
B0B39_RS15445 3479431..3480282 - 852 WP_085662656.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
B0B39_RS15450 3480279..3480887 - 609 WP_059428262.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
B0B39_RS15455 3481367..3482299 + 933 Protein_3013 IS4 family transposase -
B0B39_RS15460 3482770..3485610 + 2841 WP_003634933.1 aconitate hydratase AcnA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 3481355..3482299 944


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(35-262)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(9-56)


Sequences

Toxin        


Download         Length: 284 a.a.        Molecular weight: 31791.70 Da        Isoelectric Point: 6.7348

>T75644 WP_085662656.1 NZ_CP020894:c3480282-3479431 [Legionella longbeachae]
MTKNIGESVRSRLKNIAVKEGSDFNAVLTRYGLERLLYRIGESEYSKQFLLKGALLFNLWYDMPHRPTKDIDLLGFGDND
LAYVKQTFSKICRISTDDGISFLSESVTVDTIKKDGGYTGARVELFGELAKAKIKIQIDIGYGDAVTPGPIDAHYPVLLS
DLPAPKIWTYPIYTVIAEKLHAIALLGMANSRLKDYLDLYVLLSNEQIDNQVLAKAIQATFNRRGMDLPEALPVGLTDEF
ANDPSRESMWKAFLRKNELEQKPLTEVIAVIRNLIQVPYSLAK

Download         Length: 852 bp

>T75644 NZ_CP020894:c3480282-3479431 [Legionella longbeachae]
ATGACAAAAAATATCGGTGAGTCTGTACGCTCACGTTTGAAGAATATAGCTGTAAAAGAGGGTTCTGATTTTAATGCGGT
ATTGACTCGTTATGGTCTAGAGCGTTTGTTATATCGAATTGGAGAATCAGAATATTCTAAACAGTTTTTGTTGAAAGGTG
CCTTATTATTTAACTTATGGTATGACATGCCTCATCGCCCAACTAAAGATATTGATTTATTGGGGTTTGGTGATAATGAT
CTAGCGTATGTTAAACAAACGTTCAGTAAAATTTGCAGAATCTCTACAGATGATGGAATAAGTTTCCTGTCTGAATCAGT
GACGGTTGACACTATCAAAAAAGATGGGGGTTATACTGGAGCAAGAGTTGAGTTATTTGGGGAATTGGCGAAAGCAAAGA
TTAAAATACAAATTGATATAGGTTATGGTGATGCAGTTACCCCTGGGCCAATAGATGCCCATTATCCCGTGCTTCTTAGT
GATCTTCCTGCCCCTAAAATCTGGACTTATCCAATTTATACGGTAATTGCAGAAAAGCTGCACGCAATTGCATTATTGGG
CATGGCGAATAGTCGATTAAAAGACTACTTGGATCTTTATGTATTATTAAGTAATGAACAGATAGATAACCAAGTCTTGG
CTAAAGCTATACAGGCTACATTTAATCGTCGAGGTATGGATCTTCCTGAAGCGCTGCCTGTTGGCCTGACCGATGAGTTT
GCTAACGATCCAAGCAGGGAATCAATGTGGAAAGCCTTTTTGAGAAAAAATGAACTAGAGCAGAAACCATTAACTGAAGT
TATTGCTGTGATCAGAAATTTGATTCAAGTGCCATATTCTTTGGCAAAGTAA

Antitoxin


Download         Length: 203 a.a.        Molecular weight: 23005.88 Da        Isoelectric Point: 9.2813

>AT75644 WP_059428262.1 NZ_CP020894:c3480887-3480279 [Legionella longbeachae]
MKTEATYKQKVLQMASKTGIVRMSDLTERGITRATISRLVSENKLEKLASGLYCLPETEFSEKESLVIIASRVPQAVFCL
LTALQIHDLTTQLPRKVWIAMPKGSHAPKMDYPPLKMVQYSDEAFSEGIEIIESDNIRLRVYNRGKTIADCFKHRNKIGL
DVAIEALKEAYTKNKVTVDELWHYAKICRVANVMRPYIEAIQ

Download         Length: 609 bp

>AT75644 NZ_CP020894:c3480887-3480279 [Legionella longbeachae]
ATGAAGACTGAAGCTACCTATAAACAAAAAGTACTCCAGATGGCTAGTAAAACCGGCATTGTTCGAATGTCCGATCTAAC
CGAAAGGGGGATCACTAGAGCGACCATTTCAAGGCTTGTTAGCGAAAACAAACTTGAAAAACTCGCTTCTGGGCTCTATT
GCTTGCCCGAGACTGAGTTTTCAGAAAAAGAAAGCCTAGTTATTATAGCAAGCCGAGTACCTCAAGCAGTGTTTTGCCTG
CTAACTGCTTTGCAGATTCATGATCTAACAACACAGCTACCTCGAAAAGTATGGATAGCTATGCCAAAAGGGAGCCATGC
GCCAAAAATGGATTATCCTCCGCTAAAAATGGTGCAATATTCCGATGAAGCCTTTAGTGAAGGAATTGAAATTATAGAAT
CAGATAATATTAGACTAAGGGTGTATAACCGTGGCAAGACTATTGCAGATTGTTTCAAACATCGCAATAAAATTGGACTT
GATGTAGCCATTGAAGCACTTAAAGAGGCTTATACAAAGAATAAAGTTACAGTTGATGAACTATGGCATTATGCGAAAAT
TTGTCGCGTTGCAAACGTAATGCGTCCTTATATTGAGGCAATTCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References