Detailed information of TA system TA075640

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Xre(antitoxin)
• Location: 1651203..1652360
• Replicon: chromosome
• Accession: NZ_CP020892
• Organism: Pseudomonas sp. M30-35

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: B9K09_RS07745
• Protein ID: WP_087516265.1
• Coordinates: 1651608..1652360 (+)
• Length: 251 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: B9K09_RS07740
• Protein ID: WP_087516264.1
• Coordinates: 1651203..1651571 (+)
• Length: 123 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B9K09_RS07715	1646542..1647003	-	462	WP_087516259.1	MarR family transcriptional regulator	-
B9K09_RS07720	1647283..1647708	+	426	WP_087516260.1	organic hydroperoxide resistance protein	-
B9K09_RS07725	1647779..1648123	-	345	WP_087516261.1	YdbL family protein	-
B9K09_RS07730	1648135..1648326	-	192	WP_087516262.1	YnbE family lipoprotein	-
B9K09_RS07735	1648342..1650972	-	2631	WP_087516263.1	YdbH domain-containing protein	-
B9K09_RS07740	1651203..1651571	+	369	WP_087516264.1	XRE family transcriptional regulator	Antitoxin
B9K09_RS07745	1651608..1652360	+	753	WP_087516265.1	RES family NAD+ phosphorylase	Toxin
B9K09_RS07750	1652964..1653311	+	348	WP_157699387.1	SEL1-like repeat protein	-
B9K09_RS07755	1653599..1654954	+	1356	WP_177408710.1	DNA recombination protein RmuC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (61-206)

Antitoxin

• Cro/C1-type helix-turn-helix domain (16-47)

Sequences

Toxin

Protein

• Length: 251 a.a.
• Molecular weight: 28397.52 Da
• Isoelectric Point: 7.7254

>T75640 WP_087516265.1 NZ_CP020892:1651608-1652360 [Pseudomonas sp. M30-35]
MQIWQACHGPEHITALRGRLVRLVESQEQVATLQLVDTLAEQALLEEMLETSKPPLPESAQGLHYLLKTPFRYPPLRWGS
RFGSRFEPSLFYAAQRLETAMAEAAYYRFVLWDGMSVAPPSERILSEHCSFEARYKVTCGVALHKSPFDQYRAQLMHPSQ
YQQTQVLGAQMREAGVEAFEYRSARCAQGGINVALYTPRALAEKRPSNLMPWFCETTAEYVAFKNPHSAAALQVFKLTDF
QREGRLPLPA

Nucleotide

• Length: 753 bp

>T75640 NZ_CP020892:1651608-1652360 [Pseudomonas sp. M30-35]
ATGCAAATTTGGCAGGCCTGTCATGGCCCTGAACACATCACTGCGTTACGTGGCCGGCTGGTACGCTTGGTTGAGAGCCA
GGAGCAGGTTGCCACCCTGCAGTTGGTTGATACTCTGGCTGAGCAGGCATTGCTCGAAGAAATGCTCGAAACCAGTAAAC
CGCCGCTGCCTGAGTCCGCGCAGGGTTTGCACTATCTATTAAAGACGCCATTTCGTTATCCACCGCTGCGTTGGGGCTCA
CGCTTTGGTTCGCGCTTTGAGCCAAGTTTGTTTTATGCGGCTCAACGTCTGGAAACGGCGATGGCTGAGGCGGCTTATTA
TCGATTTGTGCTCTGGGATGGTATGTCCGTGGCGCCGCCCAGTGAACGAATTCTGTCTGAGCATTGCTCGTTTGAGGCGC
GCTATAAGGTGACGTGTGGCGTTGCGCTGCATAAATCACCCTTTGATCAATATCGCGCGCAGCTGATGCACCCCAGTCAA
TATCAGCAAACCCAGGTCTTAGGTGCGCAGATGCGCGAGGCTGGGGTTGAAGCATTTGAATATCGCTCAGCGCGCTGTGC
TCAAGGTGGAATCAATGTTGCGCTCTATACTCCGCGAGCGCTGGCGGAGAAGCGCCCAAGTAACCTGATGCCATGGTTTT
GTGAGACCACGGCAGAGTATGTGGCTTTCAAAAATCCGCATTCGGCTGCTGCGCTACAGGTGTTCAAGTTGACCGATTTT
CAACGAGAAGGGCGGCTACCGTTGCCCGCCTAG

Antitoxin

Protein

• Length: 123 a.a.
• Molecular weight: 13448.63 Da
• Isoelectric Point: 9.7756

>AT75640 WP_087516264.1 NZ_CP020892:1651203-1651571 [Pseudomonas sp. M30-35]
MSAKIQPVSDVDSVLAKALLNTREQLGLTQQELADIVGVHRSAISRWVDAGLNPHSKTGELALLFIRGYRALFALFGGDL
ADMRHFLRTENRHLAGVPLQMMGQVQGLVRVVEYLDAIRGKV

Nucleotide

• Length: 369 bp

>AT75640 NZ_CP020892:1651203-1651571 [Pseudomonas sp. M30-35]
ATGAGCGCAAAAATACAGCCTGTTAGCGATGTTGACAGCGTATTGGCCAAAGCGTTGCTCAATACGCGCGAGCAACTCGG
CCTTACTCAGCAAGAGCTTGCCGATATTGTCGGCGTGCACCGCAGTGCGATCAGTCGTTGGGTGGATGCAGGGTTAAATC
CGCACAGTAAAACTGGCGAGTTAGCGCTGTTGTTTATTCGCGGTTATCGCGCATTGTTCGCCCTATTTGGCGGTGACCTG
GCAGATATGCGCCATTTTTTGCGCACTGAGAACCGTCACCTGGCGGGTGTGCCTTTGCAAATGATGGGGCAAGTGCAAGG
TTTGGTGCGGGTAGTCGAATACCTCGATGCGATTCGCGGCAAGGTTTGA