Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2557143..2557504 Replicon chromosome
Accession NZ_CP020889
Organism Xanthomonas citri pv. citri strain TX160197

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag B7L67_RS11630 Protein ID WP_005914328.1
Coordinates 2557370..2557504 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag B7L67_RS11625 Protein ID WP_003486606.1
Coordinates 2557143..2557295 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7L67_RS11590 2552243..2552926 - 684 WP_011052674.1 dTMP kinase -
B7L67_RS11600 2553364..2553906 - 543 WP_003486615.1 GTPase -
B7L67_RS11605 2553903..2554820 - 918 WP_011052673.1 hypothetical protein -
B7L67_RS11610 2554917..2555276 - 360 WP_003486613.1 hypothetical protein -
B7L67_RS11615 2555340..2555792 - 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
B7L67_RS11620 2556113..2557036 + 924 WP_005927745.1 arginase -
B7L67_RS11625 2557143..2557295 + 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
B7L67_RS11630 2557370..2557504 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
B7L67_RS11635 2557731..2557940 + 210 WP_003486601.1 CsbD family protein -
B7L67_RS11640 2558121..2559410 + 1290 WP_015463705.1 tryptophan--tRNA ligase -
B7L67_RS11645 2559449..2560483 + 1035 WP_011052671.1 MBL fold metallo-hydrolase -
B7L67_RS11650 2560675..2562366 + 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T75636 WP_005914328.1 NZ_CP020889:2557370-2557504 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T75636 NZ_CP020889:2557370-2557504 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT75636 WP_003486606.1 NZ_CP020889:2557143-2557295 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT75636 NZ_CP020889:2557143-2557295 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References