Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2111834..2112501 Replicon chromosome
Accession NZ_CP020889
Organism Xanthomonas citri pv. citri strain TX160197

Toxin (Protein)


Gene name vapC Uniprot ID M4U0C6
Locus tag B7L67_RS09715 Protein ID WP_005916679.1
Coordinates 2112085..2112501 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID M4U000
Locus tag B7L67_RS09710 Protein ID WP_005916676.1
Coordinates 2111834..2112088 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7L67_RS09685 2107955..2108174 + 220 Protein_1786 RNA 2'-phosphotransferase -
B7L67_RS09690 2108331..2109596 + 1266 WP_015463799.1 cardiolipin synthase B -
B7L67_RS09695 2109622..2110149 - 528 WP_005916668.1 hypothetical protein -
B7L67_RS09700 2110388..2110594 + 207 WP_003489327.1 hypothetical protein -
B7L67_RS09705 2110581..2111687 + 1107 WP_005916674.1 type II toxin-antitoxin system RelE/ParE family toxin -
B7L67_RS09710 2111834..2112088 + 255 WP_005916676.1 Arc family DNA-binding protein Antitoxin
B7L67_RS09715 2112085..2112501 + 417 WP_005916679.1 type II toxin-antitoxin system VapC family toxin Toxin
B7L67_RS25610 2112623..2112895 - 273 WP_125459513.1 hypothetical protein -
B7L67_RS25615 2112954..2113166 - 213 WP_015472901.1 hypothetical protein -
B7L67_RS09720 2113423..2115042 + 1620 WP_015463800.1 hypothetical protein -
B7L67_RS09725 2115146..2115544 - 399 WP_004429277.1 DUF2384 domain-containing protein -
B7L67_RS09730 2115860..2116291 + 432 WP_005922907.1 hypothetical protein -
B7L67_RS09735 2116320..2116646 - 327 Protein_1798 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-127)

Antitoxin

Arc-like DNA binding domain

(1-39)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14795.09 Da        Isoelectric Point: 5.6920

>T75635 WP_005916679.1 NZ_CP020889:2112085-2112501 [Xanthomonas citri pv. citri]
VILLDTNVISELWRPQPNPQVVAWIDAQAVETLFLSVVTVAELRFGIAVMPKGRKRSTLHARLEGEVLPLFDGRLLAFDL
DASHAFAALASKARTAGLTLGRADAYIAATAAAQGLTVATRDTAPFEAMALDVINPWS

Download         Length: 417 bp

>T75635 NZ_CP020889:2112085-2112501 [Xanthomonas citri pv. citri]
GTGATCCTGCTCGATACCAATGTCATCTCCGAACTTTGGCGGCCTCAGCCTAATCCGCAGGTCGTCGCCTGGATCGATGC
ACAAGCTGTCGAGACACTGTTCCTGTCGGTCGTGACGGTGGCTGAACTCCGTTTCGGTATTGCCGTGATGCCCAAGGGCC
GAAAGCGATCCACCTTGCATGCTCGGTTGGAGGGCGAGGTATTGCCACTGTTCGACGGGCGCCTGCTCGCATTCGATCTG
GATGCATCACACGCATTTGCGGCGCTTGCATCGAAAGCCAGAACCGCAGGACTCACACTCGGGCGCGCCGATGCCTACAT
CGCTGCAACAGCAGCCGCGCAAGGATTGACCGTTGCCACTCGCGACACGGCACCATTCGAGGCGATGGCGTTAGACGTCA
TTAACCCTTGGAGTTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 8996.53 Da        Isoelectric Point: 11.3362

>AT75635 WP_005916676.1 NZ_CP020889:2111834-2112088 [Xanthomonas citri pv. citri]
MPSFTVRNIPDDVHRAIRARAALHGRSTEAEIRAILELAAKPADRVKLGSLLVSIGRDAGLTAKEANAFDKLRGKAAIKP
IGLK

Download         Length: 255 bp

>AT75635 NZ_CP020889:2111834-2112088 [Xanthomonas citri pv. citri]
ATGCCTTCTTTCACCGTCCGCAATATCCCAGACGACGTGCATCGCGCGATCCGCGCGCGGGCTGCACTTCATGGCCGCAG
CACCGAAGCGGAGATCCGCGCAATCCTTGAATTGGCGGCCAAACCCGCAGACCGGGTCAAACTCGGCTCACTGCTGGTGA
GCATCGGCCGCGACGCCGGCCTGACCGCAAAAGAGGCCAATGCCTTCGACAAGCTGCGCGGCAAGGCGGCGATCAAGCCG
ATCGGTCTGAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB M4U0C6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YKJ0

References