Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 612828..613495 Replicon chromosome
Accession NZ_CP020882
Organism Xanthomonas citri pv. citri strain TX160042

Toxin (Protein)


Gene name vapC Uniprot ID M4U0C6
Locus tag B7L65_RS02685 Protein ID WP_005916679.1
Coordinates 612828..613244 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID M4U000
Locus tag B7L65_RS02690 Protein ID WP_005916676.1
Coordinates 613241..613495 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7L65_RS02665 608683..609009 + 327 Protein_482 hypothetical protein -
B7L65_RS02670 609038..609469 - 432 WP_005922907.1 hypothetical protein -
B7L65_RS02675 609785..610183 + 399 WP_004429277.1 DUF2384 domain-containing protein -
B7L65_RS02680 610287..611906 - 1620 WP_015463800.1 hypothetical protein -
B7L65_RS25360 612163..612375 + 213 WP_015472901.1 hypothetical protein -
B7L65_RS25365 612434..612706 + 273 WP_125459513.1 hypothetical protein -
B7L65_RS02685 612828..613244 - 417 WP_005916679.1 type II toxin-antitoxin system VapC family toxin Toxin
B7L65_RS02690 613241..613495 - 255 WP_005916676.1 Arc family DNA-binding protein Antitoxin
B7L65_RS02695 613642..614748 - 1107 WP_005916674.1 type II toxin-antitoxin system RelE/ParE family toxin -
B7L65_RS02700 614735..614941 - 207 WP_003489327.1 hypothetical protein -
B7L65_RS02705 615180..615707 + 528 WP_005916668.1 hypothetical protein -
B7L65_RS02710 615733..616998 - 1266 WP_015463799.1 cardiolipin synthase B -
B7L65_RS02715 617155..617374 - 220 Protein_494 RNA 2'-phosphotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-127)

Antitoxin

Arc-like DNA binding domain

(1-39)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14795.09 Da        Isoelectric Point: 5.6920

>T75620 WP_005916679.1 NZ_CP020882:c613244-612828 [Xanthomonas citri pv. citri]
VILLDTNVISELWRPQPNPQVVAWIDAQAVETLFLSVVTVAELRFGIAVMPKGRKRSTLHARLEGEVLPLFDGRLLAFDL
DASHAFAALASKARTAGLTLGRADAYIAATAAAQGLTVATRDTAPFEAMALDVINPWS

Download         Length: 417 bp

>T75620 NZ_CP020882:c613244-612828 [Xanthomonas citri pv. citri]
GTGATCCTGCTCGATACCAATGTCATCTCCGAACTTTGGCGGCCTCAGCCTAATCCGCAGGTCGTCGCCTGGATCGATGC
ACAAGCTGTCGAGACACTGTTCCTGTCGGTCGTGACGGTGGCTGAACTCCGTTTCGGTATTGCCGTGATGCCCAAGGGCC
GAAAGCGATCCACCTTGCATGCTCGGTTGGAGGGCGAGGTATTGCCACTGTTCGACGGGCGCCTGCTCGCATTCGATCTG
GATGCATCACACGCATTTGCGGCGCTTGCATCGAAAGCCAGAACCGCAGGACTCACACTCGGGCGCGCCGATGCCTACAT
CGCTGCAACAGCAGCCGCGCAAGGATTGACCGTTGCCACTCGCGACACGGCACCATTCGAGGCGATGGCGTTAGACGTCA
TTAACCCTTGGAGTTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 8996.53 Da        Isoelectric Point: 11.3362

>AT75620 WP_005916676.1 NZ_CP020882:c613495-613241 [Xanthomonas citri pv. citri]
MPSFTVRNIPDDVHRAIRARAALHGRSTEAEIRAILELAAKPADRVKLGSLLVSIGRDAGLTAKEANAFDKLRGKAAIKP
IGLK

Download         Length: 255 bp

>AT75620 NZ_CP020882:c613495-613241 [Xanthomonas citri pv. citri]
ATGCCTTCTTTCACCGTCCGCAATATCCCAGACGACGTGCATCGCGCGATCCGCGCGCGGGCTGCACTTCATGGCCGCAG
CACCGAAGCGGAGATCCGCGCAATCCTTGAATTGGCGGCCAAACCCGCAGACCGGGTCAAACTCGGCTCACTGCTGGTGA
GCATCGGCCGCGACGCCGGCCTGACCGCAAAAGAGGCCAATGCCTTCGACAAGCTGCGCGGCAAGGCGGCGATCAAGCCG
ATCGGTCTGAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB M4U0C6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YKJ0

References