Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 167820..168181 Replicon chromosome
Accession NZ_CP020882
Organism Xanthomonas citri pv. citri strain TX160042

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag B7L65_RS00765 Protein ID WP_005914328.1
Coordinates 167820..167954 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag B7L65_RS00770 Protein ID WP_003486606.1
Coordinates 168029..168181 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7L65_RS00745 162958..164649 - 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -
B7L65_RS00750 164841..165875 - 1035 WP_011052671.1 MBL fold metallo-hydrolase -
B7L65_RS00755 165914..167203 - 1290 WP_015463705.1 tryptophan--tRNA ligase -
B7L65_RS00760 167384..167593 - 210 WP_003486601.1 CsbD family protein -
B7L65_RS00765 167820..167954 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
B7L65_RS00770 168029..168181 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
B7L65_RS00775 168288..169211 - 924 WP_005927745.1 arginase -
B7L65_RS00780 169532..169984 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
B7L65_RS00785 170048..170407 + 360 WP_003486613.1 hypothetical protein -
B7L65_RS00790 170504..171421 + 918 WP_011052673.1 hypothetical protein -
B7L65_RS00795 171418..171960 + 543 WP_003486615.1 GTPase -
B7L65_RS00805 172398..173081 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T75619 WP_005914328.1 NZ_CP020882:c167954-167820 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T75619 NZ_CP020882:c167954-167820 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT75619 WP_003486606.1 NZ_CP020882:c168181-168029 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT75619 NZ_CP020882:c168181-168029 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References