Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1067549..1068351 Replicon chromosome
Accession NZ_CP020873
Organism Prosthecochloris sp. HL-130-GSB

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag B9H02_RS05130 Protein ID WP_085659488.1
Coordinates 1067549..1068076 (-) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag B9H02_RS05135 Protein ID WP_085660586.1
Coordinates 1068073..1068351 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B9H02_RS05115 1063010..1065973 + 2964 WP_198166405.1 DEAD/DEAH box helicase family protein -
B9H02_RS05120 1066257..1067123 + 867 WP_085659487.1 hypothetical protein -
B9H02_RS11750 1067386..1067496 + 111 WP_198166406.1 hypothetical protein -
B9H02_RS05130 1067549..1068076 - 528 WP_085659488.1 GNAT family N-acetyltransferase Toxin
B9H02_RS05135 1068073..1068351 - 279 WP_085660586.1 DUF1778 domain-containing protein Antitoxin
B9H02_RS05140 1068891..1069832 + 942 Protein_994 CoA ester lyase -
B9H02_RS05145 1069929..1072472 - 2544 WP_198166407.1 aminopeptidase N -
B9H02_RS05150 1072706..1073350 + 645 WP_085659490.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(11-88)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19214.99 Da        Isoelectric Point: 9.8287

>T75614 WP_085659488.1 NZ_CP020873:c1068076-1067549 [Prosthecochloris sp. HL-130-GSB]
MTISSWHEEAIASHHNRKAFDCGDKKLNEFLTRYARQNHTKGTARTFLAISDATEQAILGYYSLSITTVTYAQTPDSIKR
GLSRQAVPMFRLCRLAVNHSIQRQGLGGQLLLAAGRRCLHASSHVGGVGLLIDAKNYDVASWYASYGALPLPDTPLSLVL
PFQTIRISLESAGKL

Download         Length: 528 bp

>T75614 NZ_CP020873:c1068076-1067549 [Prosthecochloris sp. HL-130-GSB]
ATGACCATCAGTTCCTGGCACGAAGAGGCTATAGCAAGTCATCATAATCGAAAAGCCTTCGATTGCGGTGACAAGAAACT
CAATGAGTTCTTAACACGATATGCGAGGCAGAACCACACAAAGGGAACGGCGAGAACGTTTCTGGCGATCAGCGACGCTA
CAGAGCAGGCTATCCTGGGATATTATAGCCTGAGCATCACAACCGTCACCTATGCTCAAACGCCAGACAGTATCAAACGA
GGACTCAGTCGCCAGGCTGTGCCCATGTTCAGGCTGTGCAGACTTGCCGTAAACCACTCCATTCAAAGGCAAGGACTTGG
AGGGCAATTACTGCTGGCAGCGGGCAGAAGATGCTTGCATGCTTCCAGTCATGTCGGAGGAGTCGGATTGCTTATCGATG
CCAAAAACTATGATGTCGCATCCTGGTATGCAAGCTATGGGGCTCTGCCGTTGCCAGATACCCCCCTTTCTCTCGTTCTG
CCATTCCAGACGATCCGCATATCTCTGGAATCAGCGGGAAAACTCTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10245.70 Da        Isoelectric Point: 7.3195

>AT75614 WP_085660586.1 NZ_CP020873:c1068351-1068073 [Prosthecochloris sp. HL-130-GSB]
MPRTPVKSHQRLSIRIDASQKELLMRAASIQSTDLTDFVTRSSVSAAHAIIEQHERLILTEQETTYLLNLLEDPPTPNEK
LKAAASALPSRP

Download         Length: 279 bp

>AT75614 NZ_CP020873:c1068351-1068073 [Prosthecochloris sp. HL-130-GSB]
ATGCCTCGGACTCCGGTTAAAAGCCATCAGCGCCTTTCAATACGAATAGATGCCTCGCAAAAGGAGTTGCTTATGCGTGC
AGCATCTATCCAGTCCACCGATTTGACGGACTTCGTAACCAGATCCTCTGTTTCAGCGGCTCACGCAATCATAGAACAGC
ACGAACGCCTCATACTCACCGAACAGGAAACGACGTATCTGCTCAACCTGCTTGAAGATCCTCCGACACCAAATGAAAAA
CTCAAAGCAGCCGCATCAGCACTACCGTCACGTCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References