Detailed information of TA system TA075613

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pasABC/RelE-HTH
• Location: 136745..137237
• Replicon: chromosome
• Accession: NZ_CP020873
• Organism: Prosthecochloris sp. HL-130-GSB

Toxin (Protein)

• Gene name: pasB
• Uniprot ID: -
• Locus tag: B9H02_RS00650
• Protein ID: WP_085660487.1
• Coordinates: 136977..137237 (+)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: -
• Locus tag: B9H02_RS00645
• Protein ID: WP_198166369.1
• Coordinates: 136745..136993 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B9H02_RS00640	134385..136208	+	1824	WP_085658807.1	B12-binding domain-containing radical SAM protein	-
B9H02_RS00645	136745..136993	+	249	WP_198166369.1	ribbon-helix-helix protein, CopG family	Antitoxin
B9H02_RS00650	136977..137237	+	261	WP_085660487.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
B9H02_RS00655	137518..139716	-	2199	WP_085660489.1	catalase/peroxidase HPI	-
B9H02_RS00660	139876..140279	-	404	Protein_120	transcriptional repressor	-
B9H02_RS00665	140508..141656	+	1149	WP_085658808.1	hypothetical protein	-
B9H02_RS00670	141733..142085	+	353	Protein_122	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-85)

Antitoxin

• Relaxosome protein TraY (16-56)

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 9973.60 Da
• Isoelectric Point: 10.7583

>T75613 WP_085660487.1 NZ_CP020873:136977-137237 [Prosthecochloris sp. HL-130-GSB]
MVWTIEFAASAEKELSKLDKSAAKRILKFLRERVATDPRSSGKALRGDHAGLWRYRIGDYRVICEIRDQTVSVLVVRIGH
RKEVYR

Nucleotide

• Length: 261 bp

>T75613 NZ_CP020873:136977-137237 [Prosthecochloris sp. HL-130-GSB]
TTGGTCTGGACGATTGAGTTTGCCGCGTCGGCGGAAAAGGAGCTGTCCAAACTTGATAAATCTGCGGCTAAACGGATTCT
CAAATTCCTGAGAGAGCGCGTTGCCACTGATCCCCGCTCATCGGGCAAAGCGTTGCGTGGCGATCATGCCGGACTTTGGC
GGTATCGAATCGGAGATTATCGGGTGATTTGCGAAATCCGGGATCAGACCGTTTCGGTTCTTGTCGTTCGGATCGGGCAT
CGGAAAGAGGTTTATCGGTAG

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9568.87 Da
• Isoelectric Point: 4.7582

>AT75613 WP_198166369.1 NZ_CP020873:136745-136993 [Prosthecochloris sp. HL-130-GSB]
MEKEKADQMIGIRIPKSVGQRLDNLAKRTGRTKTWYVREAIMAHLDDLEDIYLAEQVLERVRRGEEAVSEIDEVERRLGL
DD

Nucleotide

• Length: 249 bp

>AT75613 NZ_CP020873:136745-136993 [Prosthecochloris sp. HL-130-GSB]
ATGGAAAAGGAAAAGGCGGATCAGATGATCGGAATTCGTATTCCGAAGAGTGTCGGCCAACGGCTGGATAACCTTGCCAA
AAGAACTGGCCGAACCAAGACCTGGTATGTGCGCGAGGCTATCATGGCACACCTCGATGATCTTGAAGATATCTATCTGG
CAGAACAGGTTCTTGAACGTGTGAGGCGTGGAGAAGAGGCTGTGTCTGAAATAGATGAGGTTGAGCGCCGTCTTGGTCTG
GACGATTGA