Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/dnstrm_HI1420(antitoxin)
Location 1699528..1700284 Replicon chromosome
Accession NZ_CP020872
Organism Dickeya fangzhongdai strain PA1

Toxin (Protein)


Gene name dhiT Uniprot ID -
Locus tag B6N31_RS07535 Protein ID WP_107759008.1
Coordinates 1699528..1699785 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID -
Locus tag B6N31_RS07540 Protein ID WP_121479931.1
Coordinates 1699793..1700284 (+) Length 164 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B6N31_RS07525 1696303..1698453 - 2151 WP_049854965.1 formate dehydrogenase subunit alpha -
B6N31_RS07530 1698488..1699030 - 543 WP_013317225.1 4Fe-4S dicluster domain-containing protein -
B6N31_RS07535 1699528..1699785 + 258 WP_107759008.1 DUF4160 domain-containing protein Toxin
B6N31_RS07540 1699793..1700284 + 492 WP_121479931.1 addiction module antitoxin Antitoxin
B6N31_RS07545 1700684..1701106 + 423 WP_121479932.1 TIR domain-containing protein -
B6N31_RS07550 1701284..1702516 + 1233 WP_121479933.1 DUF4071 domain-containing protein -
B6N31_RS07555 1702579..1703076 - 498 WP_038918521.1 hydrogenase maturation peptidase HycI -
B6N31_RS07560 1703069..1703467 - 399 WP_121479934.1 formate hydrogenlyase maturation HycH family protein -
B6N31_RS07565 1703464..1704255 - 792 WP_038918522.1 NADH-quinone oxidoreductase subunit B family protein -
B6N31_RS07570 1704252..1704821 - 570 WP_039691199.1 hydrogenase 4 subunit H -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(9-74)

Antitoxin

Uncharacterized protein HI1420

(79-157)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9995.55 Da        Isoelectric Point: 8.1489

>T75603 WP_107759008.1 NZ_CP020872:1699528-1699785 [Dickeya fangzhongdai]
MPEIDRLAGLIFHLYFYDDERHHLPHVHVCYGNHELIISIRTGTEIEGYLPNNKRKMALAHIRAHREQLLSMWERAVVGR
NPGKL

Download         Length: 258 bp

>T75603 NZ_CP020872:1699528-1699785 [Dickeya fangzhongdai]
ATGCCTGAGATTGACAGACTGGCAGGGCTAATTTTCCATTTGTACTTTTACGATGATGAACGGCACCACTTGCCGCATGT
GCATGTCTGCTACGGCAACCATGAGCTGATCATCAGTATTCGTACTGGAACAGAGATCGAAGGATATCTGCCGAATAACA
AGCGCAAGATGGCGCTTGCGCATATCAGAGCCCATCGGGAACAACTGCTGAGTATGTGGGAGCGGGCGGTAGTGGGGAGA
AATCCGGGAAAATTGTGA

Antitoxin


Download         Length: 164 a.a.        Molecular weight: 18069.63 Da        Isoelectric Point: 6.6448

>AT75603 WP_121479931.1 NZ_CP020872:1699793-1700284 [Dickeya fangzhongdai]
MHKIVEVDVIGDFSLRLTYEDGLVCDINLYQYASSPVFSNASLFIKFGLLPDGSLEWSPDIKISASELRKKGEYVSHTLA
VREKNFADVISRAFYDAVIENRPEILQAALKIAVEKHGNSTVAKEAGAKSRTSLYKSLNKNTHVSLATVVSLAHTVLQLE
EKE

Download         Length: 492 bp

>AT75603 NZ_CP020872:1699793-1700284 [Dickeya fangzhongdai]
ATGCATAAAATCGTGGAAGTTGACGTGATTGGCGACTTTTCGTTGCGCCTGACCTATGAGGATGGTTTGGTTTGCGACAT
CAATCTTTATCAATATGCCTCCAGCCCGGTATTTTCGAACGCCAGCCTATTTATCAAGTTTGGGCTGCTGCCGGATGGTT
CGCTGGAATGGTCGCCGGATATTAAGATTTCCGCGTCGGAATTGCGGAAAAAAGGGGAGTATGTCAGCCACACGCTTGCG
GTGCGAGAAAAGAACTTCGCTGATGTCATCTCTCGCGCCTTCTATGATGCCGTGATTGAAAACCGGCCGGAAATTCTGCA
AGCGGCGTTGAAAATCGCGGTGGAAAAACATGGCAACAGCACAGTAGCCAAAGAGGCGGGGGCGAAAAGTCGCACCAGTC
TGTATAAGTCGCTGAATAAAAATACCCATGTCAGTCTTGCGACGGTGGTCAGCCTGGCGCATACCGTACTGCAACTGGAA
GAGAAAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References