Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-YefM
Location 997986..998518 Replicon chromosome
Accession NZ_CP020857
Organism Cellulosimicrobium sp. TH-20

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag B8281_RS04530 Protein ID WP_034653831.1
Coordinates 997986..998264 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag B8281_RS04535 Protein ID WP_198163206.1
Coordinates 998261..998518 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B8281_RS04505 993654..994826 - 1173 WP_085387032.1 histidine kinase -
B8281_RS04510 994895..995878 + 984 WP_085387033.1 iron-siderophore ABC transporter substrate-binding protein -
B8281_RS04515 995865..996791 + 927 WP_085387034.1 siderophore-interacting protein -
B8281_RS19415 996769..997389 - 621 WP_085387035.1 hypothetical protein -
B8281_RS19420 997484..997963 + 480 WP_198163145.1 META domain-containing protein -
B8281_RS04530 997986..998264 - 279 WP_034653831.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
B8281_RS04535 998261..998518 - 258 WP_198163206.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
B8281_RS04540 998619..999137 - 519 WP_085387037.1 hypothetical protein -
B8281_RS04545 999142..999603 - 462 WP_085387038.1 hypothetical protein -
B8281_RS19160 999622..999882 - 261 WP_108049967.1 YbdD/YjiX family protein -
B8281_RS04555 999885..1002182 - 2298 WP_021481587.1 carbon starvation protein A -
B8281_RS04560 1002352..1002933 + 582 WP_009863291.1 GNAT family N-acetyltransferase -
B8281_RS04565 1002893..1003495 - 603 WP_085387039.1 TetR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-66)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10281.87 Da        Isoelectric Point: 8.9088

>T75577 WP_034653831.1 NZ_CP020857:c998264-997986 [Cellulosimicrobium sp. TH-20]
VTDVDGGWEVRLSPPAARMLYQLPPRLADAVIRFCDEPLASNPYRVTKALGAELAGQRAGYVGIGFRVLVRIDDDQRLVT
VMRMAYRADAYR

Download         Length: 279 bp

>T75577 NZ_CP020857:c998264-997986 [Cellulosimicrobium sp. TH-20]
GTGACCGACGTCGACGGTGGGTGGGAGGTGCGCCTGAGCCCACCGGCCGCGCGCATGCTCTACCAGCTCCCACCACGCCT
GGCCGACGCCGTGATCCGCTTCTGCGACGAACCACTTGCGTCGAACCCCTACCGGGTGACGAAGGCGCTCGGGGCCGAGC
TCGCCGGCCAGCGCGCCGGGTACGTCGGGATCGGGTTCCGCGTCCTGGTCCGCATCGACGACGACCAGCGACTGGTCACC
GTGATGCGGATGGCCTACCGCGCCGACGCCTACCGGTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9151.26 Da        Isoelectric Point: 4.3671

>AT75577 WP_198163206.1 NZ_CP020857:c998518-998261 [Cellulosimicrobium sp. TH-20]
MSEAKTNLSALVDEVESTHQPVTITRHGKAAAVLIAPEDLATLMETLAWLSDPDHAAEMAEAEEAVAQGRTLSLAEVREQ
LASRR

Download         Length: 258 bp

>AT75577 NZ_CP020857:c998518-998261 [Cellulosimicrobium sp. TH-20]
ATGAGCGAAGCGAAGACCAACCTGTCCGCCCTGGTCGACGAGGTGGAGAGCACCCACCAACCGGTGACGATCACCCGTCA
CGGGAAGGCAGCGGCGGTGCTGATCGCGCCGGAAGACCTGGCGACGCTCATGGAGACGCTGGCATGGCTGTCCGACCCGG
ACCACGCGGCCGAGATGGCCGAGGCCGAGGAGGCGGTGGCGCAGGGCCGCACCCTGAGCCTCGCTGAGGTGCGCGAGCAG
CTGGCCTCGCGACGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References