Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 442975..443119 Replicon chromosome
Accession NZ_CP020847
Organism Klebsiella variicola strain KPN1481

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 442981..443083 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 442975..443119 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B8O08_RS02175 438497..439930 + 1434 WP_086892585.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
B8O08_RS02180 440046..440285 + 240 WP_002911393.1 YebV family protein -
B8O08_RS02185 440383..440574 + 192 WP_002911395.1 YebW family protein -
B8O08_RS02190 440571..441224 - 654 WP_022066249.1 protein-serine/threonine phosphatase -
B8O08_RS02195 441360..442349 + 990 WP_032691211.1 VirK/YbjX family protein -
B8O08_RS31350 442453..442596 + 144 WP_048268691.1 Ecr family regulatory small membrane protein -
- 442975..443119 + 145 - - Antitoxin
- 442981..443083 - 103 - - Toxin
B8O08_RS02205 443241..443579 - 339 WP_008804271.1 YebY family protein -
B8O08_RS02210 443596..444464 - 869 Protein_431 copper homeostasis membrane protein CopD -
B8O08_RS02215 444468..444842 - 375 WP_012541261.1 CopC domain-containing protein YobA -
B8O08_RS02220 444956..445186 + 231 WP_012541260.1 DNA polymerase III subunit theta -
B8O08_RS02225 445265..445924 + 660 WP_012541259.1 exodeoxyribonuclease X -
B8O08_RS02230 445928..447988 - 2061 WP_012541258.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T75532 NZ_CP020847:c443083-442981 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT75532 NZ_CP020847:442975-443119 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References