Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1214619..1214764 Replicon chromosome
Accession NZ_CP020841
Organism Klebsiella pneumoniae strain KPN1482

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1214626..1214728 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1214619..1214764 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B8O09_RS06250 1210152..1211585 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
B8O09_RS06255 1211701..1211940 + 240 WP_002911393.1 YebV family protein -
B8O09_RS06260 1212038..1212229 + 192 WP_002911395.1 YebW family protein -
B8O09_RS06265 1212226..1212879 - 654 WP_071570906.1 protein-serine/threonine phosphatase -
B8O09_RS06270 1213036..1214004 + 969 WP_168786284.1 VirK/YbjX family protein -
B8O09_RS30845 1214109..1214252 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1214619..1214764 + 146 - - Antitoxin
- 1214626..1214728 - 103 - - Toxin
B8O09_RS06280 1214887..1215225 - 339 WP_004189269.1 YebY family protein -
B8O09_RS06285 1215242..1216111 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
B8O09_RS06290 1216115..1216489 - 375 WP_004151448.1 CopC domain-containing protein YobA -
B8O09_RS06295 1216602..1216832 + 231 WP_002911406.1 DNA polymerase III subunit theta -
B8O09_RS06300 1216911..1217570 + 660 WP_002911407.1 exodeoxyribonuclease X -
B8O09_RS06305 1217574..1219634 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T75509 NZ_CP020841:c1214728-1214626 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT75509 NZ_CP020841:1214619-1214764 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References