Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 3506379..3508053 Replicon chromosome
Accession NZ_CP020820
Organism Pantoea vagans strain FBS135

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag B9D02_RS16710 Protein ID WP_110411683.1
Coordinates 3507145..3508053 (+) Length 303 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag B9D02_RS16705 Protein ID WP_110411682.1
Coordinates 3506379..3507152 (+) Length 258 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B9D02_RS16665 3501857..3502681 - 825 WP_197711767.1 CDP-diacylglycerol diphosphatase -
B9D02_RS16670 3502742..3503050 - 309 WP_078804790.1 hypothetical protein -
B9D02_RS16675 3503069..3503494 - 426 WP_078804791.1 hypothetical protein -
B9D02_RS16680 3503491..3504192 - 702 WP_039658871.1 hypothetical protein -
B9D02_RS16685 3504347..3504703 - 357 WP_110411681.1 hypothetical protein -
B9D02_RS16695 3505270..3505599 - 330 WP_078804792.1 endoribonuclease SymE -
- 3505617..3505670 + 54 NuclAT_0 - -
- 3505617..3505670 + 54 NuclAT_0 - -
- 3505617..3505670 + 54 NuclAT_0 - -
- 3505617..3505670 + 54 NuclAT_0 - -
- 3505617..3505670 + 54 NuclAT_1 - -
- 3505617..3505670 + 54 NuclAT_1 - -
- 3505617..3505670 + 54 NuclAT_1 - -
- 3505617..3505670 + 54 NuclAT_1 - -
B9D02_RS16700 3505859..3505989 - 131 Protein_3221 restriction endonuclease subunit S -
B9D02_RS16705 3506379..3507152 + 774 WP_110411682.1 type IV toxin-antitoxin system AbiEi family antitoxin Antitoxin
B9D02_RS16710 3507145..3508053 + 909 WP_110411683.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
B9D02_RS16715 3508274..3508486 + 213 WP_110411684.1 integrase core domain-containing protein -
B9D02_RS16720 3508567..3508740 + 174 Protein_3225 DUF45 domain-containing protein -
B9D02_RS16725 3508779..3510260 - 1482 WP_078804795.1 N-6 DNA methylase -
B9D02_RS16730 3510253..3510855 - 603 WP_078804796.1 restriction endonuclease subunit S -
B9D02_RS16735 3510872..3511060 - 189 WP_110411685.1 hypothetical protein -
B9D02_RS16740 3511322..3512569 - 1248 WP_110411686.1 integrase arm-type DNA-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3503491..3512569 9078


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(13-278)

Antitoxin

Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system

(95-246)


Sequences

Toxin        


Download         Length: 303 a.a.        Molecular weight: 34143.04 Da        Isoelectric Point: 4.7427

>T75457 WP_110411683.1 NZ_CP020820:3507145-3508053 [Pantoea vagans]
MDKTSPYYRQVSLLVRALPYVANETCFALKGGTAINLFIRDFPRLSVDIDLAYIPLESREVALPNVRKALSRIVAELETQ
AGIGAVPQTHNPDEMRIIATTDDAQIKIEVSPVARGTLYPPQERDVVEAVEEEFGFAAIPVVSLPDLYGGKLCAALDRQH
PRDFYDVKMLLDTQGIDRAIFNGFIAYLLSHNRPLSEVLSPRWKDINEPFQNEFSGMTLDEVSLEALGEVPERMLSALKA
HFTQQDFDFLMSFKRGEPDWNLAPESHIQNLPAVQWKLRNIGQMNEEKRVQSLNKLEKVMAE

Download         Length: 909 bp

>T75457 NZ_CP020820:3507145-3508053 [Pantoea vagans]
ATGGATAAAACCTCCCCCTACTACCGCCAGGTCTCCCTGCTGGTTAGAGCATTACCCTATGTCGCTAACGAGACCTGTTT
TGCGCTGAAAGGGGGAACCGCAATCAACTTATTCATTCGCGATTTTCCCCGATTGTCCGTTGATATCGATCTGGCTTATA
TCCCACTGGAAAGCAGAGAGGTCGCCTTACCCAACGTGCGGAAAGCGCTAAGCCGCATCGTCGCTGAACTGGAAACACAA
GCCGGGATCGGTGCAGTGCCGCAAACCCATAATCCCGATGAGATGCGTATCATAGCCACTACGGACGACGCGCAAATTAA
AATCGAGGTTTCACCCGTTGCCCGGGGAACATTGTATCCACCGCAAGAACGCGACGTCGTGGAAGCTGTGGAAGAAGAGT
TTGGTTTTGCCGCGATCCCGGTAGTCTCACTGCCTGATCTATATGGCGGCAAGCTATGTGCTGCGTTAGATCGACAACAT
CCCAGAGATTTCTACGACGTTAAAATGCTCCTTGATACACAAGGAATCGACCGCGCAATATTCAATGGCTTTATCGCTTA
TTTGCTTAGCCATAATCGCCCCTTATCCGAAGTTCTTAGCCCACGCTGGAAAGATATTAACGAACCCTTTCAAAATGAAT
TCAGCGGTATGACCCTTGATGAAGTCTCACTGGAAGCGCTGGGAGAGGTCCCGGAAAGAATGCTTAGTGCGCTGAAAGCG
CATTTCACTCAACAGGATTTCGACTTCCTGATGTCATTTAAACGCGGAGAACCTGACTGGAATTTAGCACCAGAATCCCA
CATTCAGAATTTACCAGCCGTTCAATGGAAGCTGCGAAATATAGGACAGATGAATGAGGAAAAGCGCGTGCAGTCGCTGA
ATAAACTGGAAAAGGTCATGGCAGAATGA

Antitoxin


Download         Length: 258 a.a.        Molecular weight: 29232.64 Da        Isoelectric Point: 10.1733

>AT75457 WP_110411682.1 NZ_CP020820:3506379-3507152 [Pantoea vagans]
MPSKINWLLQNTSPGSLVLQSWLTRNNISPSLAYKYAQSGWLKKLRAGVYARAGREPDWSDALWSLQSQLDAPVHLAGLS
SLSWQGRSHYLQLKQSQCWLSVENKTILPKWFKEFPGVEWLIVSALKLPQLDEKFRTELDVKGKKLTASVPELAAYELLS
AVPQVISFEHAAELFQGLVNLNPRKVEKLLTLSQSVQTKRLYLFFASFYDHAWFRRVDTSKIDLGSGNRQVVVNGKLDTQ
YMITVPENFNRKGISHG

Download         Length: 774 bp

>AT75457 NZ_CP020820:3506379-3507152 [Pantoea vagans]
ATGCCATCAAAAATAAACTGGCTATTGCAAAACACCTCTCCAGGAAGCCTGGTTTTGCAATCCTGGCTAACCCGGAACAA
CATATCGCCTTCTCTGGCCTATAAATACGCGCAAAGTGGCTGGCTGAAAAAACTGCGGGCTGGCGTTTATGCGCGCGCAG
GACGAGAACCGGACTGGAGTGATGCGCTATGGAGTCTTCAAAGCCAGCTTGACGCGCCAGTGCATCTGGCCGGACTGAGC
AGCCTCTCCTGGCAGGGCCGTTCCCATTACCTGCAACTTAAGCAGAGTCAATGCTGGCTTAGCGTTGAAAACAAAACAAT
ATTGCCTAAATGGTTTAAAGAATTTCCCGGCGTTGAGTGGCTGATAGTATCAGCTCTGAAGCTTCCTCAACTGGATGAGA
AGTTCCGAACCGAGCTCGACGTTAAAGGAAAAAAATTAACTGCCAGCGTACCAGAGCTGGCAGCCTATGAGCTGTTAAGC
GCAGTCCCTCAGGTAATCTCATTCGAGCACGCTGCCGAGCTTTTTCAGGGACTGGTCAATCTCAATCCACGTAAAGTCGA
GAAGCTACTTACGCTCAGTCAGTCCGTACAAACAAAGCGATTGTATCTGTTTTTCGCCAGTTTTTATGATCATGCCTGGT
TCAGGCGCGTAGATACCAGCAAAATCGACCTGGGATCGGGTAACCGACAAGTTGTTGTCAATGGCAAGCTGGACACGCAG
TACATGATTACTGTGCCCGAAAATTTTAACAGGAAGGGAATAAGCCATGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References