Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2877277..2877938 Replicon chromosome
Accession NZ_CP020818
Organism Bordetella bronchiseptica strain F709

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag B9G73_RS13560 Protein ID WP_033459448.1
Coordinates 2877513..2877938 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag B9G73_RS13555 Protein ID WP_003812071.1
Coordinates 2877277..2877516 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B9G73_RS13520 2872312..2873115 - 804 WP_003817085.1 bacteriocin family protein -
B9G73_RS13525 2873112..2874158 - 1047 WP_003817082.1 Dyp-type peroxidase -
B9G73_RS13530 2874236..2874796 - 561 WP_033459449.1 DUF488 domain-containing protein -
B9G73_RS13535 2874793..2875026 - 234 WP_033448627.1 DUF2945 domain-containing protein -
B9G73_RS13540 2875107..2875619 - 513 WP_033448625.1 redoxin domain-containing protein -
B9G73_RS13545 2875678..2876223 - 546 WP_033461208.1 peroxidase-related enzyme -
B9G73_RS13550 2876361..2877203 + 843 WP_003817077.1 AraC family transcriptional regulator -
B9G73_RS13555 2877277..2877516 + 240 WP_003812071.1 Arc family DNA-binding protein Antitoxin
B9G73_RS13560 2877513..2877938 + 426 WP_033459448.1 PIN domain-containing protein Toxin
B9G73_RS13565 2878048..2878512 + 465 WP_003812075.1 MarR family transcriptional regulator -
B9G73_RS13570 2878618..2880123 - 1506 WP_003812078.1 tripartite tricarboxylate transporter permease -
B9G73_RS13575 2880622..2881134 + 513 WP_033461205.1 hypothetical protein -
B9G73_RS13580 2881154..2882131 - 978 WP_003817071.1 tripartite tricarboxylate transporter substrate binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin

Arc-like DNA binding domain

(9-46)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 14873.23 Da        Isoelectric Point: 6.3721

>T75442 WP_033459448.1 NZ_CP020818:2877513-2877938 [Bordetella bronchiseptica]
MILLDTDVLLEPLRPAPDPAVAAWLDAQHVETLYLAAPGAAEIQLGLARLPRGKRAEALRHEFERRILPLFMGHVLPFDA
AAADAYAAVMMRAAAAGHALCATDGYIAAIATAHGLAIATRHPARFEAAGLTAVDPWHAAA

Download         Length: 426 bp

>T75442 NZ_CP020818:2877513-2877938 [Bordetella bronchiseptica]
ATGATCCTGCTCGACACCGACGTGCTGCTCGAACCGCTGCGGCCGGCCCCCGACCCGGCCGTCGCGGCATGGCTGGATGC
CCAGCACGTCGAAACCCTGTACCTGGCCGCGCCCGGCGCGGCCGAAATCCAGCTCGGGCTGGCCCGTCTGCCGCGCGGCA
AGCGGGCCGAGGCCCTGCGCCACGAATTCGAGCGGCGCATCCTGCCGCTGTTCATGGGCCATGTCCTGCCTTTCGACGCG
GCCGCGGCCGATGCCTACGCCGCCGTCATGATGCGGGCCGCGGCGGCGGGCCATGCGCTGTGCGCGACCGATGGCTACAT
CGCCGCCATCGCCACCGCGCACGGCCTGGCCATCGCCACGCGCCATCCGGCCAGGTTCGAGGCGGCCGGGCTCACTGCCG
TCGATCCCTGGCACGCCGCCGCTTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8561.78 Da        Isoelectric Point: 11.5658

>AT75442 WP_003812071.1 NZ_CP020818:2877277-2877516 [Bordetella bronchiseptica]
VSSITVRNVPEEVHRALRVRAATHGRSTEAEIRAILENAVLPDGRVKLGTLLSHIGRGARGMDLTIERNPAPARPASFE

Download         Length: 240 bp

>AT75442 NZ_CP020818:2877277-2877516 [Bordetella bronchiseptica]
GTGTCTTCGATTACGGTAAGAAATGTTCCCGAGGAAGTGCATCGCGCCTTGCGCGTACGCGCGGCCACACATGGGCGCAG
CACCGAGGCCGAGATCCGCGCCATCCTGGAAAACGCCGTGCTGCCCGATGGCCGCGTCAAACTGGGCACCCTGCTCAGCC
ACATCGGCCGCGGCGCGCGCGGCATGGACCTGACCATCGAGCGCAATCCGGCGCCCGCCCGCCCGGCCAGCTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References