Detailed information of TA system TA075427

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): KacT-ataR/DUF1778(antitoxin)
• Location: 1639162..1639959
• Replicon: chromosome
• Accession: NZ_CP020817
• Organism: Enterobacter sp. Crenshaw

Toxin (Protein)

• Gene name: KacT
• Uniprot ID: -
• Locus tag: B7P19_RS07840
• Protein ID: WP_172620298.1
• Coordinates: 1639459..1639959 (+)
• Length: 167 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: B7P19_RS07835
• Protein ID: WP_023311079.1
• Coordinates: 1639162..1639431 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B7P19_RS07805	1634789..1635232	-	444	WP_032658095.1	helix-turn-helix transcriptional regulator	-
B7P19_RS07810	1635385..1636626	+	1242	WP_048979071.1	bifunctional glucose-1-phosphatase/inositol phosphatase	-
B7P19_RS07815	1636660..1636887	-	228	WP_008499832.1	YccJ family protein	-
B7P19_RS07820	1636908..1637504	-	597	WP_023311076.1	NAD(P)H:quinone oxidoreductase	-
B7P19_RS07825	1637895..1638065	+	171	WP_023311077.1	general stress protein	-
B7P19_RS07830	1638183..1639100	+	918	WP_048979072.1	DMT family transporter	-
B7P19_RS07835	1639162..1639431	+	270	WP_023311079.1	DUF1778 domain-containing protein	Antitoxin
B7P19_RS07840	1639459..1639959	+	501	WP_172620298.1	GNAT family N-acetyltransferase	Toxin
B7P19_RS07845	1640033..1641355	-	1323	WP_048979074.1	pyrimidine utilization transport protein G	-
B7P19_RS07850	1641377..1641871	-	495	WP_048979075.1	pyrimidine utilization flavin reductase protein F	-
B7P19_RS07855	1641881..1642471	-	591	WP_033145164.1	malonic semialdehyde reductase	-
B7P19_RS07860	1642481..1643281	-	801	WP_048979076.1	pyrimidine utilization protein D	-
B7P19_RS07865	1643289..1643675	-	387	WP_010429508.1	pyrimidine utilization protein C	-
B7P19_RS07870	1643687..1644376	-	690	WP_033145167.1	pyrimidine utilization protein B	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Vibrio phage ICP1, Orf50 (2-88)

Sequences

Toxin

Protein

• Length: 167 a.a.
• Molecular weight: 19018.74 Da
• Isoelectric Point: 7.9108

>T75427 WP_172620298.1 NZ_CP020817:1639459-1639959 [Enterobacter sp. Crenshaw]
MLSEGTDYDFEYFDCGEPSLNAFLAEHLVRQHNGRILRAYLLKERDRPRVLGYYTLSGSCFERAMLPSKTQQRRIPYINV
PSVTLGRLAVDKTLQGNEWGTTLVAHAMRVVYLASQAVGVHGIFVDALDERAKRFYLKQGFIPLTAENSHSLFFPTKSIE
RLFEQE

Nucleotide

• Length: 501 bp

>T75427 NZ_CP020817:1639459-1639959 [Enterobacter sp. Crenshaw]
ATGTTATCAGAGGGAACCGATTATGACTTCGAGTATTTTGATTGTGGCGAACCCTCGCTAAATGCCTTCCTTGCTGAACA
TCTGGTGCGTCAGCACAATGGGCGTATTTTACGAGCCTACCTGCTTAAAGAGCGCGATCGTCCGCGTGTCCTGGGTTATT
ACACGTTATCGGGAAGCTGTTTTGAAAGAGCGATGCTTCCTTCTAAGACTCAGCAGCGCCGGATCCCTTATATCAACGTA
CCCAGCGTGACGCTGGGACGTCTGGCTGTAGATAAAACCCTACAGGGAAACGAGTGGGGAACAACGCTCGTTGCGCATGC
TATGCGCGTTGTCTACCTGGCTTCACAGGCTGTGGGGGTACACGGAATATTTGTTGATGCCCTTGACGAGCGGGCAAAAC
GATTTTATCTGAAGCAGGGCTTTATCCCGCTGACAGCTGAAAACAGCCATTCTTTGTTCTTCCCTACAAAATCTATCGAA
CGGCTGTTTGAGCAAGAGTGA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 10249.72 Da
• Isoelectric Point: 5.8836

>AT75427 WP_023311079.1 NZ_CP020817:1639162-1639431 [Enterobacter sp. Crenshaw]
MPALKKQRIDLRLTDEDKTMIEEAAAMTNQTITQFMVNSASERAAEVIEQHRRLVLNEASWTAVMDAIDNPPEPNERLKR
AAKRLRNME

Nucleotide

• Length: 270 bp

>AT75427 NZ_CP020817:1639162-1639431 [Enterobacter sp. Crenshaw]
ATGCCAGCACTTAAAAAACAGCGTATCGATCTTCGCTTAACGGACGAAGACAAAACAATGATTGAAGAAGCGGCGGCGAT
GACGAACCAAACGATCACCCAGTTTATGGTGAACAGTGCGTCAGAGCGTGCTGCAGAGGTCATCGAGCAGCACCGTCGTC
TCGTATTAAACGAAGCATCATGGACTGCGGTGATGGATGCCATCGACAATCCGCCTGAGCCAAATGAACGCCTGAAACGA
GCAGCAAAACGGCTTCGAAACATGGAGTGA