Detailed information of TA system TA075410

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN(toxin)
• Location: 4767919..4768367
• Replicon: chromosome
• Accession: NZ_CP020771
• Organism: Microcystis aeruginosa PCC 7806SL

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: BH695_RS23665
• Protein ID: WP_002748554.1
• Coordinates: 4767919..4768125 (-)
• Length: 69 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: BH695_RS23670
• Protein ID: WP_036402927.1
• Coordinates: 4768125..4768367 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BH695_RS23655	4763359..4765155	+	1797	WP_002748559.1	N-acetylmuramoyl-L-alanine amidase	-
BH695_RS23660	4765841..4767937	+	2097	WP_002748555.1	phosphate acetyltransferase	-
BH695_RS23665	4767919..4768125	-	207	WP_002748554.1	hypothetical protein	Toxin
BH695_RS23670	4768125..4768367	-	243	WP_036402927.1	DUF2281 domain-containing protein	Antitoxin
BH695_RS23675	4768400..4768669	-	270	WP_002792733.1	type II toxin-antitoxin system RelE/ParE family toxin	-
BH695_RS23680	4768677..4768892	-	216	WP_002748551.1	hypothetical protein	-
BH695_RS27380	4768946..4769107	-	162	WP_002748550.1	hypothetical protein	-
BH695_RS23685	4769098..4770966	+	1869	WP_002748548.1	cation:proton antiporter	-
BH695_RS23690	4770984..4771847	-	864	WP_002748546.1	hypothetical protein	-
BH695_RS23695	4771918..4772451	+	534	WP_002748538.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Domain of unknown function DUF2281 (7-79)

Sequences

Toxin

Protein

• Length: 69 a.a.
• Molecular weight: 7772.98 Da
• Isoelectric Point: 4.2493

>T75410 WP_002748554.1 NZ_CP020771:c4768125-4767919 [Microcystis aeruginosa PCC 7806SL]
MKSALIDTHVFIWLAEDDPILPVSLRDSLENTDNVFVSIASFWEISIKVKIGKLSLCSEMTMTQKDWD

Nucleotide

• Length: 207 bp

>T75410 NZ_CP020771:c4768125-4767919 [Microcystis aeruginosa PCC 7806SL]
ATGAAGAGTGCTTTAATAGATACTCATGTCTTTATCTGGTTAGCTGAGGATGACCCAATTTTGCCTGTTTCGCTGCGAGA
TAGTCTTGAAAATACCGATAATGTTTTTGTAAGTATTGCTAGTTTTTGGGAAATATCGATCAAGGTAAAAATTGGTAAAC
TCTCTCTCTGTTCTGAAATGACCATGACTCAAAAAGATTGGGATTGA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9051.25 Da
• Isoelectric Point: 4.6158

>AT75410 WP_036402927.1 NZ_CP020771:c4768367-4768125 [Microcystis aeruginosa PCC 7806SL]
MSIDSALKNIVENMPDALKTELLHYAEYLLTKSDRTEEDKQAAKESVTVKRTLASSIKGTFVLPLANDFDAPLEDFKDYR

Nucleotide

• Length: 243 bp

>AT75410 NZ_CP020771:c4768367-4768125 [Microcystis aeruginosa PCC 7806SL]
ATGAGTATAGATTCAGCCCTTAAGAATATAGTTGAGAATATGCCCGATGCTCTCAAAACTGAACTTTTACATTATGCCGA
ATATTTGCTCACTAAGTCTGACCGAACAGAAGAAGATAAACAAGCAGCAAAAGAATCTGTAACTGTTAAAAGAACTTTAG
CCAGTTCAATAAAAGGAACTTTCGTTTTACCTTTAGCTAATGACTTTGATGCTCCCTTAGAAGACTTTAAGGACTATAGG
TAA