Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | VII | Classification (family/domain) | HepT-MntA/HepT(toxin) |
Location | 3930369..3931228 | Replicon | chromosome |
Accession | NZ_CP020771 | ||
Organism | Microcystis aeruginosa PCC 7806SL |
Toxin (Protein)
Gene name | hepT | Uniprot ID | A0A1X9LDD0 |
Locus tag | BH695_RS19480 | Protein ID | WP_002742889.1 |
Coordinates | 3930369..3930767 (-) | Length | 133 a.a. |
Antitoxin (Protein)
Gene name | mntA | Uniprot ID | A0A1X9LBQ1 |
Locus tag | BH695_RS19485 | Protein ID | WP_002742890.1 |
Coordinates | 3930809..3931228 (-) | Length | 140 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BH695_RS19470 | 3926250..3929696 | - | 3447 | WP_002742886.1 | type I-D CRISPR-associated protein Cas10d/Csc3 | - |
BH695_RS26340 | 3929689..3929914 | - | 226 | Protein_3701 | DUF86 domain-containing protein | - |
BH695_RS19475 | 3929918..3930376 | - | 459 | WP_036400372.1 | nucleotidyltransferase domain-containing protein | - |
BH695_RS19480 | 3930369..3930767 | - | 399 | WP_002742889.1 | DUF86 domain-containing protein | Toxin |
BH695_RS19485 | 3930809..3931228 | - | 420 | WP_002742890.1 | nucleotidyltransferase domain-containing protein | Antitoxin |
BH695_RS19490 | 3931391..3931738 | - | 348 | WP_002742891.1 | hypothetical protein | - |
BH695_RS19495 | 3932084..3932326 | - | 243 | WP_002742893.1 | hypothetical protein | - |
BH695_RS19500 | 3932373..3934538 | - | 2166 | WP_084990033.1 | type I-D CRISPR-associated helicase Cas3' | - |
BH695_RS19505 | 3934637..3935500 | + | 864 | WP_002742899.1 | WYL domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 133 a.a. Molecular weight: 15324.59 Da Isoelectric Point: 4.6345
>T75407 WP_002742889.1 NZ_CP020771:c3930767-3930369 [Microcystis aeruginosa PCC 7806SL]
MNQYLAELSEYGSITLEDYRTLRERQLAIERLIQLIIQTGIDINYQILKCLDIESPNNARDALFQIVELGILEEHLAVQL
AESIKLRNLLVHLYKKIDPDIVHSSIANILRDYPRYQRSIVQFLDSLEAENG
MNQYLAELSEYGSITLEDYRTLRERQLAIERLIQLIIQTGIDINYQILKCLDIESPNNARDALFQIVELGILEEHLAVQL
AESIKLRNLLVHLYKKIDPDIVHSSIANILRDYPRYQRSIVQFLDSLEAENG
Download Length: 399 bp
>T75407 NZ_CP020771:c3930767-3930369 [Microcystis aeruginosa PCC 7806SL]
ATGAATCAATACCTCGCCGAACTTAGCGAGTACGGTTCGATCACCTTAGAGGATTATCGTACATTAAGAGAACGTCAATT
AGCCATAGAAAGGTTAATTCAGCTTATCATTCAAACTGGCATCGATATCAATTACCAGATTTTAAAATGTTTAGATATCG
AGTCTCCGAATAATGCTCGCGACGCATTATTTCAGATCGTAGAACTGGGAATTTTAGAAGAACACCTAGCCGTTCAACTG
GCCGAGTCTATTAAATTAAGAAACTTACTCGTACACCTATACAAGAAAATTGATCCCGATATTGTTCATTCCTCGATCGC
TAATATTTTACGAGATTATCCTCGCTACCAACGCTCGATCGTTCAATTTCTAGATTCCTTGGAGGCAGAAAATGGTTAA
ATGAATCAATACCTCGCCGAACTTAGCGAGTACGGTTCGATCACCTTAGAGGATTATCGTACATTAAGAGAACGTCAATT
AGCCATAGAAAGGTTAATTCAGCTTATCATTCAAACTGGCATCGATATCAATTACCAGATTTTAAAATGTTTAGATATCG
AGTCTCCGAATAATGCTCGCGACGCATTATTTCAGATCGTAGAACTGGGAATTTTAGAAGAACACCTAGCCGTTCAACTG
GCCGAGTCTATTAAATTAAGAAACTTACTCGTACACCTATACAAGAAAATTGATCCCGATATTGTTCATTCCTCGATCGC
TAATATTTTACGAGATTATCCTCGCTACCAACGCTCGATCGTTCAATTTCTAGATTCCTTGGAGGCAGAAAATGGTTAA
Antitoxin
Download Length: 140 a.a. Molecular weight: 16307.78 Da Isoelectric Point: 5.1063
>AT75407 WP_002742890.1 NZ_CP020771:c3931228-3930809 [Microcystis aeruginosa PCC 7806SL]
MNRLVEKITAIVEKLPNLKLLILFGSRARREHRPDSDWDFAVLYEERSDQKDISSLLKIYTLLEQALEIPEDKIDVVDLK
ECSPILAHYVARDGQLLYERETGLFEGFKEKFLMNPEESKALYRQLRNNLEISLREKGV
MNRLVEKITAIVEKLPNLKLLILFGSRARREHRPDSDWDFAVLYEERSDQKDISSLLKIYTLLEQALEIPEDKIDVVDLK
ECSPILAHYVARDGQLLYERETGLFEGFKEKFLMNPEESKALYRQLRNNLEISLREKGV
Download Length: 420 bp
>AT75407 NZ_CP020771:c3931228-3930809 [Microcystis aeruginosa PCC 7806SL]
ATGAATAGGCTAGTAGAAAAAATTACGGCTATTGTCGAAAAACTACCGAATTTAAAACTATTAATTCTCTTCGGTTCTAG
AGCGCGTAGAGAGCATAGACCTGATAGCGATTGGGATTTCGCTGTTTTATACGAGGAAAGAAGCGATCAAAAGGATATTT
CGAGTCTGTTGAAAATTTATACACTGCTCGAACAAGCTTTAGAGATTCCCGAGGACAAAATTGATGTGGTTGATTTAAAA
GAATGTTCGCCGATCCTCGCTCATTATGTCGCACGGGATGGTCAACTTCTATACGAACGGGAAACGGGACTATTCGAGGG
ATTTAAAGAAAAATTTCTCATGAATCCTGAAGAATCGAAAGCGTTATACCGTCAATTACGGAATAATCTAGAGATTTCTC
TACGAGAAAAAGGAGTGTAA
ATGAATAGGCTAGTAGAAAAAATTACGGCTATTGTCGAAAAACTACCGAATTTAAAACTATTAATTCTCTTCGGTTCTAG
AGCGCGTAGAGAGCATAGACCTGATAGCGATTGGGATTTCGCTGTTTTATACGAGGAAAGAAGCGATCAAAAGGATATTT
CGAGTCTGTTGAAAATTTATACACTGCTCGAACAAGCTTTAGAGATTCCCGAGGACAAAATTGATGTGGTTGATTTAAAA
GAATGTTCGCCGATCCTCGCTCATTATGTCGCACGGGATGGTCAACTTCTATACGAACGGGAAACGGGACTATTCGAGGG
ATTTAAAGAAAAATTTCTCATGAATCCTGAAGAATCGAAAGCGTTATACCGTCAATTACGGAATAATCTAGAGATTTCTC
TACGAGAAAAAGGAGTGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1X9LDD0 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1X9LBQ1 |