Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1887764..1887998 | Replicon | chromosome |
| Accession | NZ_CP020753 | ||
| Organism | Shigella flexneri 1c strain Y394 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1887765..1887868 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1887764..1887998 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| B7485_RS09780 | 1883299..1883571 | + | 273 | WP_001277358.1 | host-nuclease inhibitor Gam family protein | - |
| B7485_RS09785 | 1883601..1884698 | + | 1098 | WP_128882124.1 | AAA family ATPase | - |
| B7485_RS09790 | 1884749..1884937 | + | 189 | WP_000276807.1 | DUF1187 family protein | - |
| - | 1884755..1884933 | - | 179 | NuclAT_0 | - | - |
| - | 1884755..1884933 | - | 179 | NuclAT_0 | - | - |
| - | 1884755..1884933 | - | 179 | NuclAT_0 | - | - |
| - | 1884755..1884933 | - | 179 | NuclAT_0 | - | - |
| B7485_RS09795 | 1885038..1886193 | + | 1156 | WP_134797305.1 | IS3-like element IS600 family transposase | - |
| B7485_RS09800 | 1886310..1886591 | + | 282 | WP_005127484.1 | excisionase | - |
| B7485_RS09805 | 1886557..1887633 | + | 1077 | Protein_1906 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 1887764..1887998 | + | 235 | - | - | Antitoxin |
| - | 1887765..1887868 | - | 104 | - | - | Toxin |
| B7485_RS09810 | 1888026..1888367 | - | 342 | WP_000976476.1 | YebY family protein | - |
| B7485_RS09815 | 1888380..1889252 | - | 873 | Protein_1908 | copper homeostasis membrane protein CopD | - |
| B7485_RS09820 | 1889256..1889630 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| B7485_RS09825 | 1889769..1889999 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| B7485_RS09830 | 1890101..1890757 | + | 657 | Protein_1911 | carbon-nitrogen hydrolase family protein YobB | - |
| B7485_RS09835 | 1890781..1891443 | + | 663 | WP_000944270.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 | 1872831..1945699 | 72868 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T75388 NZ_CP020753:c1887868-1887765 [Shigella flexneri 1c]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT75388 NZ_CP020753:1887764-1887998 [Shigella flexneri 1c]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
