Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 7683..8719 | Replicon | plasmid p3SUD7 |
| Accession | NZ_CP020697 | ||
| Organism | Sulfitobacter sp. D7 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | A0A386TJD0 |
| Locus tag | B5M07_RS18105 | Protein ID | WP_065331084.1 |
| Coordinates | 8144..8719 (+) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | - |
| Locus tag | B5M07_RS18100 | Protein ID | WP_120352552.1 |
| Coordinates | 7683..8147 (+) | Length | 155 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| B5M07_RS18075 | 3908..4165 | + | 258 | WP_064225038.1 | type II toxin-antitoxin system ParD family antitoxin | - |
| B5M07_RS18080 | 4162..4497 | + | 336 | WP_064225037.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| B5M07_RS18085 | 4504..5619 | - | 1116 | WP_065331088.1 | tyrosine-type recombinase/integrase | - |
| B5M07_RS18090 | 5776..6660 | + | 885 | WP_065331087.1 | DUF1403 family protein | - |
| B5M07_RS18095 | 6663..7277 | + | 615 | WP_065331086.1 | SMC-Scp complex subunit ScpB | - |
| B5M07_RS18100 | 7683..8147 | + | 465 | WP_120352552.1 | helix-turn-helix domain-containing protein | Antitoxin |
| B5M07_RS18105 | 8144..8719 | + | 576 | WP_065331084.1 | PIN domain-containing protein | Toxin |
| B5M07_RS18115 | 9092..9457 | + | 366 | WP_065331083.1 | transposase | - |
| B5M07_RS18120 | 9454..9801 | + | 348 | WP_017467473.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| B5M07_RS18125 | 9871..11574 | + | 1704 | WP_065331082.1 | IS66 family transposase | - |
| B5M07_RS18130 | 11607..11936 | + | 330 | WP_017467358.1 | quaternary ammonium compound efflux SMR transporter SugE | - |
| B5M07_RS19525 | 11996..12337 | - | 342 | WP_065331081.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..104922 | 104922 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 20927.78 Da Isoelectric Point: 4.5612
>T75292 WP_065331084.1 NZ_CP020697:8144-8719 [Sulfitobacter sp. D7]
MSRHADRFTALLDACVLGGALRRNMLLSLAEAGLFRPRWSSRILDETQKAITQITKGETDGSRQRAAIEAAFPEALVTGY
EIFEDKLALPDPNDNHVLAAAIATSASVIVTDNLADFPSAVLDPHSIQAISADDFIADTIELDPSEAIMALRRMRERFKN
PALDVATLIHKSEAQGLLQVATFMDEYQSFL
MSRHADRFTALLDACVLGGALRRNMLLSLAEAGLFRPRWSSRILDETQKAITQITKGETDGSRQRAAIEAAFPEALVTGY
EIFEDKLALPDPNDNHVLAAAIATSASVIVTDNLADFPSAVLDPHSIQAISADDFIADTIELDPSEAIMALRRMRERFKN
PALDVATLIHKSEAQGLLQVATFMDEYQSFL
Download Length: 576 bp
>T75292 NZ_CP020697:8144-8719 [Sulfitobacter sp. D7]
ATGAGCCGACACGCTGATCGGTTCACGGCGCTCCTCGATGCCTGCGTCCTGGGCGGAGCGCTTCGCAGAAACATGCTCCT
GAGCCTGGCCGAGGCTGGTTTGTTCCGGCCTCGGTGGAGCAGTCGCATCCTTGACGAGACTCAGAAAGCGATCACCCAGA
TCACCAAGGGCGAAACCGATGGGTCCCGGCAAAGGGCGGCAATCGAGGCAGCATTCCCTGAAGCTCTGGTGACTGGTTAT
GAGATCTTCGAAGACAAGCTCGCGTTACCCGACCCCAACGACAACCACGTGCTGGCAGCGGCCATCGCGACGTCTGCTTC
AGTCATCGTGACGGACAATCTTGCCGACTTTCCTTCCGCGGTTCTGGACCCGCACTCCATCCAGGCGATTTCCGCCGACG
ACTTCATCGCCGATACAATCGAGTTGGATCCCTCCGAGGCCATAATGGCCCTGCGCCGGATGAGGGAGCGCTTCAAGAAT
CCGGCGCTCGATGTCGCGACATTGATCCACAAGTCCGAAGCGCAGGGCTTGTTGCAGGTCGCAACCTTCATGGACGAGTA
CCAGTCGTTCTTGTGA
ATGAGCCGACACGCTGATCGGTTCACGGCGCTCCTCGATGCCTGCGTCCTGGGCGGAGCGCTTCGCAGAAACATGCTCCT
GAGCCTGGCCGAGGCTGGTTTGTTCCGGCCTCGGTGGAGCAGTCGCATCCTTGACGAGACTCAGAAAGCGATCACCCAGA
TCACCAAGGGCGAAACCGATGGGTCCCGGCAAAGGGCGGCAATCGAGGCAGCATTCCCTGAAGCTCTGGTGACTGGTTAT
GAGATCTTCGAAGACAAGCTCGCGTTACCCGACCCCAACGACAACCACGTGCTGGCAGCGGCCATCGCGACGTCTGCTTC
AGTCATCGTGACGGACAATCTTGCCGACTTTCCTTCCGCGGTTCTGGACCCGCACTCCATCCAGGCGATTTCCGCCGACG
ACTTCATCGCCGATACAATCGAGTTGGATCCCTCCGAGGCCATAATGGCCCTGCGCCGGATGAGGGAGCGCTTCAAGAAT
CCGGCGCTCGATGTCGCGACATTGATCCACAAGTCCGAAGCGCAGGGCTTGTTGCAGGTCGCAACCTTCATGGACGAGTA
CCAGTCGTTCTTGTGA
Antitoxin
Download Length: 155 a.a. Molecular weight: 17124.56 Da Isoelectric Point: 4.7979
>AT75292 WP_120352552.1 NZ_CP020697:7683-8147 [Sulfitobacter sp. D7]
MNALRKEAFFDRLPDEVEIKNAEQLRTIVASQIKEGEPTKLSLALEDGEVRTVTLAPALTASLLEVLRLVSSGRGFRMIP
VESELTTQQAADLLNVSRPFLVKLLEEGEIPFAKTGRHRRVRADDLFTYKEKRDASRSDALSDLAAMDAEEGLV
MNALRKEAFFDRLPDEVEIKNAEQLRTIVASQIKEGEPTKLSLALEDGEVRTVTLAPALTASLLEVLRLVSSGRGFRMIP
VESELTTQQAADLLNVSRPFLVKLLEEGEIPFAKTGRHRRVRADDLFTYKEKRDASRSDALSDLAAMDAEEGLV
Download Length: 465 bp
>AT75292 NZ_CP020697:7683-8147 [Sulfitobacter sp. D7]
ATGAACGCCCTCAGAAAAGAGGCGTTCTTTGATCGTTTGCCCGACGAGGTAGAGATCAAGAACGCCGAACAACTCAGAAC
GATTGTGGCCTCCCAGATCAAGGAAGGCGAACCGACAAAGCTGTCGCTCGCCCTGGAAGACGGCGAAGTTCGCACCGTGA
CGCTTGCGCCGGCCTTGACGGCTTCGCTACTCGAAGTGCTGCGGCTTGTCTCGAGCGGTCGCGGGTTTCGGATGATCCCC
GTCGAGTCAGAGCTGACCACGCAGCAGGCGGCGGACCTTCTCAATGTGTCCCGGCCGTTCCTAGTGAAGCTTCTCGAGGA
AGGCGAGATTCCCTTTGCGAAGACCGGCCGTCATCGCCGGGTTCGTGCCGACGACCTCTTTACCTACAAGGAGAAGCGTG
ACGCGTCTCGCTCTGATGCTTTGAGTGACCTTGCTGCAATGGATGCGGAAGAAGGTCTTGTATGA
ATGAACGCCCTCAGAAAAGAGGCGTTCTTTGATCGTTTGCCCGACGAGGTAGAGATCAAGAACGCCGAACAACTCAGAAC
GATTGTGGCCTCCCAGATCAAGGAAGGCGAACCGACAAAGCTGTCGCTCGCCCTGGAAGACGGCGAAGTTCGCACCGTGA
CGCTTGCGCCGGCCTTGACGGCTTCGCTACTCGAAGTGCTGCGGCTTGTCTCGAGCGGTCGCGGGTTTCGGATGATCCCC
GTCGAGTCAGAGCTGACCACGCAGCAGGCGGCGGACCTTCTCAATGTGTCCCGGCCGTTCCTAGTGAAGCTTCTCGAGGA
AGGCGAGATTCCCTTTGCGAAGACCGGCCGTCATCGCCGGGTTCGTGCCGACGACCTCTTTACCTACAAGGAGAAGCGTG
ACGCGTCTCGCTCTGATGCTTTGAGTGACCTTGCTGCAATGGATGCGGAAGAAGGTCTTGTATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|