Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 30232..31955 Replicon plasmid p2SUD7
Accession NZ_CP020696
Organism Sulfitobacter sp. D7

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag B5M07_RS17570 Protein ID WP_092838803.1
Coordinates 30232..30873 (+) Length 214 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag B5M07_RS17575 Protein ID WP_120352483.1
Coordinates 30873..31955 (+) Length 361 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B5M07_RS17560 25628..27979 + 2352 WP_120352481.1 relaxase/mobilization nuclease domain-containing protein -
B5M07_RS17565 27988..29988 + 2001 WP_120352482.1 type IV secretory system conjugative DNA transfer family protein -
B5M07_RS17570 30232..30873 + 642 WP_092838803.1 DUF4433 domain-containing protein Toxin
B5M07_RS17575 30873..31955 + 1083 WP_120352483.1 macro domain-containing protein Antitoxin
B5M07_RS17580 32733..35378 + 2646 WP_162931911.1 hypothetical protein -
B5M07_RS17585 35597..36673 - 1077 WP_120352484.1 type IV secretion system protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..126656 126656


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(13-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 214 a.a.        Molecular weight: 24390.82 Da        Isoelectric Point: 7.1173

>T75291 WP_092838803.1 NZ_CP020696:30232-30873 [Sulfitobacter sp. D7]
MANNLTAEKALIFRITHINNVPWILRHGLHCKNSGVQDPNFVRIGNLELIQRRTARNVPVAPGGSLSDYIPFYFTPFSMM
MYNIKTGYGGIRQFPNTEIVIMASSLRGLEDRGVATVFSDRHAYLQTAQFFTSLDDLDKVDWGILQRRDFKRDVDDPEKT
DRYQAEALVHRHLPVEHLAGIVCLSENEKGTLEQQREEVGLDLKIVARPGWYF

Download         Length: 642 bp

>T75291 NZ_CP020696:30232-30873 [Sulfitobacter sp. D7]
ATGGCAAACAACTTGACCGCCGAAAAAGCTCTGATCTTCAGGATTACGCACATCAACAATGTGCCGTGGATCCTCAGGCA
TGGGCTTCATTGTAAGAATTCCGGAGTGCAAGACCCCAATTTCGTGCGAATTGGGAACCTCGAATTAATTCAGCGTCGGA
CTGCACGGAATGTACCTGTTGCACCGGGCGGATCGCTATCAGATTACATTCCGTTCTATTTCACGCCATTTTCGATGATG
ATGTACAACATCAAGACTGGCTACGGAGGAATTCGCCAGTTCCCGAACACGGAGATTGTGATCATGGCGTCCTCACTTCG
AGGGCTCGAGGATCGAGGCGTAGCAACGGTGTTTTCAGATCGCCACGCATACCTCCAGACTGCGCAATTCTTCACCTCGC
TCGACGACCTCGACAAGGTCGACTGGGGCATCCTGCAGCGTAGAGACTTCAAACGCGACGTCGATGATCCCGAAAAGACG
GATCGCTACCAGGCCGAGGCGCTCGTGCACAGGCACTTGCCAGTGGAGCACCTTGCAGGCATAGTCTGCCTGAGCGAGAA
CGAAAAAGGAACACTTGAACAGCAACGGGAGGAGGTTGGGCTCGATCTCAAGATCGTGGCGCGACCAGGCTGGTATTTCT
GA

Antitoxin


Download         Length: 361 a.a.        Molecular weight: 40331.34 Da        Isoelectric Point: 6.2994

>AT75291 WP_120352483.1 NZ_CP020696:30873-31955 [Sulfitobacter sp. D7]
MVTYTQGNLLEADVDAVVNTVNTVGIMGKGIALMFKEQFPRNFEAYARACDAGEVRTGKMFVTENKELFGPRWIINFPTK
THWRVKTKIEWVEDGLKDLVRVIREKGINSIAIPPLGCGNGGLDWRDVRPLIESALAELEGVNAIVYEPTSKYQNVAKRT
GVEKLTPARALVAEMVRRYSLLGIECSILEVQKLGWFLERGVKRFGGSDALKFRFQANKYGPYSHNLTKLLDSLDGSYLR
CDKRLADADPLDLIWFNDAKYDRVQAYLNSGEGKQFSSVLEWASATIDGFESPLGMELLATVDWMMQHDDIEPTVEGVME
GLKDWAGGEVAGQRKLKIFDRRLVAIALGQLQTSNRLPAC

Download         Length: 1083 bp

>AT75291 NZ_CP020696:30873-31955 [Sulfitobacter sp. D7]
ATGGTAACTTACACGCAAGGCAATCTTCTGGAAGCTGACGTTGACGCGGTGGTGAACACCGTGAACACGGTCGGAATCAT
GGGCAAAGGAATTGCCCTCATGTTCAAGGAGCAATTCCCACGAAACTTCGAAGCTTATGCGCGCGCCTGCGATGCAGGCG
AAGTGCGTACTGGCAAAATGTTTGTTACCGAGAACAAGGAGCTCTTCGGGCCGCGCTGGATCATCAATTTCCCGACAAAG
ACCCATTGGCGAGTGAAAACTAAGATTGAATGGGTCGAGGATGGATTGAAGGACCTTGTCCGAGTAATTCGTGAGAAGGG
AATTAATTCAATTGCGATCCCTCCACTTGGCTGTGGTAATGGTGGCCTTGACTGGCGCGATGTGCGTCCTCTTATCGAGT
CGGCATTGGCGGAACTTGAAGGGGTTAATGCCATCGTCTACGAGCCGACTTCCAAGTATCAGAATGTCGCCAAGCGCACT
GGTGTTGAGAAGCTCACCCCGGCACGCGCACTGGTGGCTGAGATGGTACGTCGGTACTCACTCCTTGGGATTGAATGCTC
GATTCTTGAGGTGCAGAAATTGGGATGGTTTCTCGAGCGCGGCGTGAAACGGTTCGGGGGTTCGGACGCACTCAAGTTCA
GGTTCCAAGCAAACAAGTACGGACCTTATTCGCATAACCTGACGAAGCTGCTCGACAGTCTCGATGGAAGTTATCTCCGG
TGCGACAAGCGCCTTGCAGATGCCGATCCCTTGGATCTCATTTGGTTCAACGACGCAAAGTATGATCGAGTGCAAGCCTA
TCTGAACTCGGGTGAAGGGAAGCAGTTCTCAAGCGTACTGGAATGGGCTTCGGCCACCATCGATGGCTTTGAGTCGCCTC
TCGGCATGGAACTTCTGGCGACTGTCGACTGGATGATGCAGCACGACGATATCGAACCGACTGTTGAGGGAGTGATGGAA
GGTCTTAAGGACTGGGCTGGCGGGGAAGTCGCTGGACAGCGCAAATTGAAGATCTTCGATCGCCGGTTGGTCGCCATAGC
TTTGGGCCAACTTCAGACATCGAACAGGCTGCCTGCCTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References