Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TacT2-ataR/DUF1778(antitoxin)
Location 491929..492596 Replicon chromosome
Accession NZ_CP020664
Organism Microcystis sp. MC19

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag B5D77_RS02545 Protein ID WP_106908221.1
Coordinates 491929..492438 (-) Length 170 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag B5D77_RS02550 Protein ID WP_008200985.1
Coordinates 492429..492596 (-) Length 56 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B5D77_RS02535 488054..491446 - 3393 WP_106908219.1 DUF499 domain-containing protein -
B5D77_RS02545 491929..492438 - 510 WP_106908221.1 GNAT family N-acetyltransferase Toxin
B5D77_RS02550 492429..492596 - 168 WP_008200985.1 DUF1778 domain-containing protein Antitoxin
B5D77_RS02555 492692..495649 - 2958 WP_106909943.1 DUF1156 domain-containing protein -
B5D77_RS02560 495724..496104 - 381 WP_002754172.1 GxxExxY protein -
B5D77_RS02565 496657..496839 + 183 WP_106909944.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(38-145)

Antitoxin

Vibrio phage ICP1, Orf50

(13-49)


Sequences

Toxin        


Download         Length: 170 a.a.        Molecular weight: 18561.42 Da        Isoelectric Point: 8.8164

>T75280 WP_106908221.1 NZ_CP020664:c492438-491929 [Microcystis sp. MC19]
MGITYTAPEPLNPEHKIDFFDCGETSLNNWLKERAIKSESTGAARTYVVCADNRVVGYYCLSTGSVMRDQAPGKIKQNMP
DPIPVIIVGRLAVDRNHQGQGLGKALIKDAVLRSLQASVIAGIRAILVHALNEKAKQFYTEKCGFISSRLDPLTLMLNLS
EAQKSLDRS

Download         Length: 510 bp

>T75280 NZ_CP020664:c492438-491929 [Microcystis sp. MC19]
TTGGGAATAACCTATACAGCACCAGAACCACTCAACCCAGAACACAAGATAGATTTCTTCGACTGCGGTGAAACAAGCTT
GAATAACTGGTTGAAAGAACGCGCAATAAAAAGTGAATCTACTGGTGCAGCACGTACCTACGTTGTTTGTGCAGACAATA
GAGTAGTCGGTTACTACTGTCTGTCCACAGGTAGTGTGATGCGCGATCAAGCTCCAGGCAAAATTAAACAAAATATGCCA
GATCCCATTCCGGTAATCATTGTGGGCAGACTGGCAGTGGACCGCAACCATCAAGGACAAGGACTTGGAAAAGCCCTCAT
CAAAGATGCCGTACTCCGAAGCTTGCAAGCTTCTGTGATTGCCGGAATTAGAGCGATTCTCGTTCACGCACTCAATGAAA
AAGCCAAACAATTCTACACAGAAAAATGTGGCTTTATATCATCCCGACTCGATCCACTAACACTAATGCTAAACCTCTCT
GAAGCCCAAAAAAGTCTTGATAGGAGCTAA

Antitoxin


Download         Length: 56 a.a.        Molecular weight: 6525.62 Da        Isoelectric Point: 10.4871

>AT75280 WP_008200985.1 NZ_CP020664:c492596-492429 [Microcystis sp. MC19]
MKITKKPHKPKSYVLDRRLFVLNKEQWEAFNEALDTPAKKNEKLAQLLSTKSPWE

Download         Length: 168 bp

>AT75280 NZ_CP020664:c492596-492429 [Microcystis sp. MC19]
ATGAAAATCACCAAAAAACCCCACAAACCCAAAAGTTATGTACTAGATCGCAGGCTATTTGTCCTCAATAAAGAACAATG
GGAAGCCTTCAATGAAGCACTTGACACTCCAGCAAAAAAAAATGAAAAGCTGGCTCAGTTATTATCCACTAAAAGCCCTT
GGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References