Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 1188163..1188982 Replicon chromosome
Accession NZ_CP020657
Organism Klebsiella sp. M5al

Toxin (Protein)


Gene name yjhX Uniprot ID A0A9E1D5M6
Locus tag BWI76_RS05655 Protein ID WP_004132607.1
Coordinates 1188163..1188420 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID A0A9E1DGJ5
Locus tag BWI76_RS05660 Protein ID WP_004132606.1
Coordinates 1188431..1188982 (+) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BWI76_RS05640 1183930..1184706 - 777 WP_004132612.1 Uxu operon transcriptional regulator -
BWI76_RS05645 1184843..1186318 - 1476 WP_004132611.1 fructuronate reductase -
BWI76_RS05650 1186395..1187579 - 1185 WP_004132609.1 mannonate dehydratase -
BWI76_RS05655 1188163..1188420 + 258 WP_004132607.1 YjhX family toxin Toxin
BWI76_RS05660 1188431..1188982 + 552 WP_004132606.1 N-acetyltransferase Antitoxin
BWI76_RS05665 1189000..1190628 + 1629 WP_064371487.1 SAM-dependent methyltransferase -
BWI76_RS05670 1190732..1192072 - 1341 WP_049088521.1 carbohydrate porin -
BWI76_RS05675 1192196..1193593 - 1398 WP_004132593.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(34-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9538.04 Da        Isoelectric Point: 11.1381

>T75260 WP_004132607.1 NZ_CP020657:1188163-1188420 [Klebsiella sp. M5al]
MNLSRQEQRTLHVLAKGGRIAHVRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

>T75260 NZ_CP020657:1188163-1188420 [Klebsiella sp. M5al]
ATGAATCTATCCCGTCAGGAACAACGTACCTTACACGTTCTCGCTAAAGGTGGCCGGATCGCGCACGTTCGCGATGCATC
AGGCCGCGTCACTTCTGTTGAATGCTACAGCCGCGAAGGGCTCCTGCTCAGCGACTGCACGCTCGCCGTTTTCAAAAAAC
TCAAAACCAAAAAGCTGATTAAGTCCGTCAACGGACAGCCCTATCGCATCAATACCACCGGGCTGAATAATGTCCGCGCA
CAGCTGGATAATCGCTAA

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 19990.89 Da        Isoelectric Point: 7.2343

>AT75260 WP_004132606.1 NZ_CP020657:1188431-1188982 [Klebsiella sp. M5al]
MTNHSFTFHVASEGDTNDILHVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGKAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGAGVGGGLIRHGIEQLKAMGSQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEALKACWMLQPLSS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp

>AT75260 NZ_CP020657:1188431-1188982 [Klebsiella sp. M5al]
ATGACAAACCACAGCTTCACTTTTCATGTCGCCTCTGAAGGCGATACCAATGACATTCTCCATGTCGAAACCCGGGCTTT
CGGCTACAGCAAAGAGGCCAGGCTGGTGGCCGATTTGCTCAACGATGAGAGCGCCTGCCCGACGTTATCGCTGCTGGCCA
GGCATAACGGAAAGGCGGTTGGGCATATTTTATTCACCCGGGCGACGTTCAAAGGGGAGCCGGACTCGCCGATGATGCAC
ATCCTTGCTCCCCTTGCGGTGGTGCCGGAATACCAGGGCGCGGGCGTTGGCGGAGGGCTTATCCGTCACGGCATTGAGCA
GTTGAAAGCCATGGGAAGCCAGACGGTATTTGTTCTGGGCCACGCCACTTACTACCCCAGGCATGGGTTTGAGCCATGCG
CGGGAGATAAAGGCTATCCGGCGCCTTATCCCATTCCCGAGGCGCTCAAAGCCTGCTGGATGCTGCAGCCGCTTTCATCT
CAGCCGCTGGGACGAACGGGTCAAATACAGTGCGCCCGGGCGTTAATGAAACCCGAGCACTGGCGCGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References