Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3004253..3004906 Replicon chromosome
Accession NZ_CP020598
Organism Acinetobacter baumannii strain WKA02

Toxin (Protein)


Gene name cptA Uniprot ID A0A5N0FZY3
Locus tag B7L35_RS14595 Protein ID WP_000607074.1
Coordinates 3004517..3004906 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag B7L35_RS14590 Protein ID WP_001288210.1
Coordinates 3004253..3004510 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7L35_RS14570 2999769..3000776 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
B7L35_RS14575 3000795..3001172 + 378 WP_001216380.1 50S ribosomal protein L17 -
B7L35_RS14580 3001353..3002843 + 1491 WP_000415136.1 NAD(P)/FAD-dependent oxidoreductase -
B7L35_RS14585 3002893..3004065 - 1173 WP_001190545.1 acyl-CoA dehydrogenase family protein -
B7L35_RS14590 3004253..3004510 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
B7L35_RS14595 3004517..3004906 + 390 WP_000607074.1 membrane protein Toxin
B7L35_RS14600 3005676..3006761 + 1086 WP_031958535.1 hypothetical protein -
B7L35_RS14605 3006839..3007405 + 567 WP_000651536.1 rhombosortase -
B7L35_RS14610 3007593..3009788 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15621.89 Da        Isoelectric Point: 10.3890

>T75177 WP_000607074.1 NZ_CP020598:3004517-3004906 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKVIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T75177 NZ_CP020598:3004517-3004906 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATCACTCACAGAACACCATT
TCTCGCGTCAAAATTTTAAAAGTAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT75177 WP_001288210.1 NZ_CP020598:3004253-3004510 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp

>AT75177 NZ_CP020598:3004253-3004510 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTCGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5N0FZY3

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References