Detailed information of TA system TA075167

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 2496087..2496740
• Replicon: chromosome
• Accession: NZ_CP020592
• Organism: Acinetobacter baumannii strain USA2

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: B7L39_RS11805
• Protein ID: WP_000607077.1
• Coordinates: 2496087..2496476 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: B7L39_RS11810
• Protein ID: WP_001288210.1
• Coordinates: 2496483..2496740 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B7L39_RS11790	2491205..2493400	-	2196	WP_001158906.1	TRAP transporter large permease subunit	-
B7L39_RS11795	2493588..2494154	-	567	WP_000651538.1	rhombosortase	-
B7L39_RS11800	2494232..2495317	-	1086	WP_000049106.1	hypothetical protein	-
B7L39_RS11805	2496087..2496476	-	390	WP_000607077.1	membrane protein	Toxin
B7L39_RS11810	2496483..2496740	-	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
B7L39_RS11815	2496928..2498100	+	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
B7L39_RS11820	2498149..2499639	-	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
B7L39_RS11825	2499821..2500198	-	378	WP_001216380.1	50S ribosomal protein L17	-
B7L39_RS11830	2500217..2501224	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T75167 WP_000607077.1 NZ_CP020592:c2496476-2496087 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T75167 NZ_CP020592:c2496476-2496087 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT75167 WP_001288210.1 NZ_CP020592:c2496740-2496483 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT75167 NZ_CP020592:c2496740-2496483 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7