Detailed information of TA system TA075165

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 3373907..3374560
• Replicon: chromosome
• Accession: NZ_CP020590
• Organism: Acinetobacter baumannii strain 15A34

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: B7L42_RS16575
• Protein ID: WP_000607077.1
• Coordinates: 3373907..3374296 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: B7L42_RS16580
• Protein ID: WP_001288210.1
• Coordinates: 3374303..3374560 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B7L42_RS16560	3369025..3371220	-	2196	WP_001158906.1	TRAP transporter large permease subunit	-
B7L42_RS16565	3371408..3371974	-	567	WP_000651538.1	rhombosortase	-
B7L42_RS16570	3372052..3373137	-	1086	WP_000049106.1	hypothetical protein	-
B7L42_RS16575	3373907..3374296	-	390	WP_000607077.1	membrane protein	Toxin
B7L42_RS16580	3374303..3374560	-	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
B7L42_RS16585	3374748..3375920	+	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
B7L42_RS16590	3375969..3377459	-	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
B7L42_RS16595	3377641..3378018	-	378	WP_001216380.1	50S ribosomal protein L17	-
B7L42_RS16600	3378037..3379044	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T75165 WP_000607077.1 NZ_CP020590:c3374296-3373907 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T75165 NZ_CP020590:c3374296-3373907 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT75165 WP_001288210.1 NZ_CP020590:c3374560-3374303 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT75165 NZ_CP020590:c3374560-3374303 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7