Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Fic(toxin)
Location 2737934..2738499 Replicon chromosome
Accession NZ_CP020570
Organism Streptomyces violaceoruber strain S21

Toxin (Protein)


Gene name doc Uniprot ID A0A1G6ZB77
Locus tag B1H20_RS11795 Protein ID WP_030113262.1
Coordinates 2737934..2738302 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID A0A1G6ZBZ4
Locus tag B1H20_RS11800 Protein ID WP_030113263.1
Coordinates 2738302..2738499 (-) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B1H20_RS11785 2735225..2735884 + 660 WP_128647692.1 hypothetical protein -
B1H20_RS11790 2735980..2737764 - 1785 WP_032757610.1 DEAD/DEAH box helicase -
B1H20_RS11795 2737934..2738302 - 369 WP_030113262.1 Fic family protein Toxin
B1H20_RS11800 2738302..2738499 - 198 WP_030113263.1 hypothetical protein Antitoxin
B1H20_RS11805 2738551..2740056 - 1506 WP_030296671.1 MFS transporter -
B1H20_RS11815 2740465..2741229 - 765 WP_030296673.1 hypothetical protein -
B1H20_RS11820 2741395..2741589 - 195 WP_030345123.1 hypothetical protein -
B1H20_RS11825 2741776..2742474 - 699 WP_158715716.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(12-117)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13697.74 Da        Isoelectric Point: 5.0965

>T75144 WP_030113262.1 NZ_CP020570:c2738302-2737934 [Streptomyces violaceoruber]
MQYLTLPELLNLTRRLGTPEVRDYGLLESALARPQASVFGQDAYPDVWQKAAALMESLARNHGLVDGNKRIAWYATWVFL
HMNGHPLDADFDVDAAERFVLAVCQGVLDMPKIAEQLPVFAR

Download         Length: 369 bp

>T75144 NZ_CP020570:c2738302-2737934 [Streptomyces violaceoruber]
ATGCAGTACCTGACCCTGCCCGAGCTGTTGAACCTGACGCGACGGCTCGGCACTCCGGAAGTTCGTGACTACGGACTGCT
GGAATCCGCACTGGCCAGACCGCAGGCGAGCGTGTTCGGCCAGGACGCGTATCCGGATGTCTGGCAGAAGGCCGCCGCTC
TCATGGAGTCCCTTGCCCGAAACCACGGGCTGGTGGACGGCAACAAGCGGATCGCGTGGTACGCGACCTGGGTCTTCCTT
CACATGAACGGCCATCCGCTCGATGCGGACTTCGATGTCGACGCGGCGGAGCGGTTCGTGTTGGCAGTGTGCCAGGGTGT
CTTGGACATGCCCAAGATCGCCGAGCAGCTTCCGGTGTTCGCCCGATAG

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7280.14 Da        Isoelectric Point: 5.0497

>AT75144 WP_030113263.1 NZ_CP020570:c2738499-2738302 [Streptomyces violaceoruber]
MAGLNLRFTDEELDSLRARAEAEGKSMQAFAHDAVITAINEHSRLFNEAADHVLKVSEELNRRLA

Download         Length: 198 bp

>AT75144 NZ_CP020570:c2738499-2738302 [Streptomyces violaceoruber]
ATGGCTGGTCTGAATCTGCGATTCACCGACGAAGAGCTGGACTCCCTGCGCGCTCGCGCCGAGGCGGAGGGGAAGAGCAT
GCAGGCGTTTGCCCACGACGCGGTGATCACCGCCATAAACGAGCACTCCCGGCTCTTCAACGAGGCTGCGGACCATGTTC
TGAAGGTCAGTGAGGAGCTGAACCGGAGGCTCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1G6ZB77

Antitoxin

Source ID Structure
AlphaFold DB A0A1G6ZBZ4

References