Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 5870938..5871460 Replicon chromosome
Accession NZ_CP020569
Organism Streptomyces gilvosporeus strain F607

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag B1H19_RS26315 Protein ID WP_083107220.1
Coordinates 5870938..5871201 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0D7CDG9
Locus tag B1H19_RS26320 Protein ID WP_030064338.1
Coordinates 5871194..5871460 (-) Length 89 a.a.

Genomic Context

B1H19_RS26295B1H19_RS26300B1H19_RS38860B1H19_RS26310B1H19_RS38865B1H19_RS26325B1H19_RS26335B1H19_RS26315B1H19_RS26320B1H19_RS26330
Location: 5866584..5867576 (993 bp)
Type: Others
Protein ID: WP_083107217.1
Location: 5867653..5868498 (846 bp)
Type: Others
Protein ID: WP_083107218.1
Location: 5868579..5868743 (165 bp)
Type: Others
Protein ID: WP_157880161.1
Location: 5869698..5870786 (1089 bp)
Type: Others
Protein ID: WP_083107219.1
Location: 5871645..5871812 (168 bp)
Type: Others
Protein ID: WP_159028141.1
Location: 5872018..5873034 (1017 bp)
Type: Others
Protein ID: WP_083107221.1
Location: 5874235..5874987 (753 bp)
Type: Others
Protein ID: WP_083107223.1
Location: 5870938..5871201 (264 bp)
Type: Toxin
Protein ID: WP_083107220.1
Location: 5871194..5871460 (267 bp)
Type: Antitoxin
Protein ID: WP_030064338.1
Location: 5873147..5873932 (786 bp)
Type: Others
Protein ID: WP_083107222.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
B1H19_RS262955866584..5867576+993WP_083107217.14-hydroxy-3-methylbut-2-enyl diphosphate reductase-
B1H19_RS263005867653..5868498+846WP_083107218.1ROK family protein-
B1H19_RS388605868579..5868743+165WP_157880161.1hypothetical protein-
B1H19_RS263105869698..5870786+1089WP_083107219.1redox-regulated ATPase YchF-
B1H19_RS263155870938..5871201-264WP_083107220.1type II toxin-antitoxin system RelE/ParE family toxinToxin
B1H19_RS263205871194..5871460-267WP_030064338.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
B1H19_RS388655871645..5871812+168WP_159028141.1hypothetical protein-
B1H19_RS263255872018..5873034+1017WP_083107221.1alpha/beta hydrolase-
B1H19_RS263305873147..5873932-786WP_083107222.1PIG-L family deacetylase-
B1H19_RS263355874235..5874987+753WP_083107223.1GntR family transcriptional regulator-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(6-59)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10071.53 Da        Isoelectric Point: 9.7855

>T75143 WP_083107220.1 NZ_CP020569:c5871201-5870938 [Streptomyces gilvosporeus]
VSDYRTVFRPEAQAELRKIPRDAALRILAKLTELEKDPYGFKTTALVSQPDRRRLRVGDYRVVYTLDNGELVVWVVHVGH
RSAVYET

Download         Length: 264 bp

>T75143 NZ_CP020569:c5871201-5870938 [Streptomyces gilvosporeus]
GTGAGTGACTACCGCACCGTCTTCCGTCCCGAGGCCCAGGCCGAACTCCGCAAAATCCCACGGGACGCCGCGCTGCGCAT
CCTGGCGAAGCTGACGGAGCTGGAAAAGGATCCGTACGGCTTCAAAACCACCGCACTCGTCTCCCAGCCGGACCGCCGCC
GCCTGCGAGTCGGCGACTACCGCGTCGTCTACACCCTCGACAACGGCGAACTGGTCGTATGGGTCGTCCACGTCGGCCAC
CGTTCCGCGGTCTACGAGACCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10230.69 Da        Isoelectric Point: 4.9473

>AT75143 WP_030064338.1 NZ_CP020569:c5871460-5871194 [Streptomyces gilvosporeus]
MTQMPIESIRDVRAHLAEVVERADRDDLPTVITRRGKEVAAVVSIEVLRKYQQWEEREINRIIDERMANRSAGIPIEDVM
KETLARSE

Download         Length: 267 bp

>AT75143 NZ_CP020569:c5871460-5871194 [Streptomyces gilvosporeus]
ATGACCCAGATGCCCATAGAGTCCATCCGCGACGTCCGCGCGCACCTGGCCGAGGTCGTCGAGCGGGCCGACCGCGACGA
TCTGCCCACCGTCATCACCCGGCGCGGCAAGGAAGTCGCGGCCGTGGTCTCGATAGAGGTCCTGCGCAAGTACCAGCAGT
GGGAAGAGCGCGAGATCAACCGCATCATCGACGAGCGCATGGCCAACCGCTCGGCCGGTATCCCCATCGAGGACGTCATG
AAGGAGACGCTGGCGCGCAGTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A0D7CDG9

References