Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 1997064..1997610 Replicon chromosome
Accession NZ_CP020566
Organism Veillonella atypica strain OK5

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag B7L28_RS09080 Protein ID WP_208604724.1
Coordinates 1997326..1997610 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag B7L28_RS09075 Protein ID WP_156931817.1
Coordinates 1997064..1997345 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7L28_RS09055 1992342..1992518 + 177 WP_156931809.1 type II toxin-antitoxin system HicA family toxin -
B7L28_RS09060 1992530..1992907 + 378 WP_156931811.1 type II toxin-antitoxin system HicB family antitoxin -
B7L28_RS09065 1992902..1993510 - 609 WP_156931813.1 tetratricopeptide repeat protein -
B7L28_RS09070 1993716..1996538 - 2823 WP_156931815.1 FAD-binding oxidoreductase -
B7L28_RS09075 1997064..1997345 + 282 WP_156931817.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
B7L28_RS09080 1997326..1997610 + 285 WP_208604724.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
B7L28_RS09085 1997949..1998746 - 798 WP_156931821.1 sulfite exporter TauE/SafE family protein -
B7L28_RS09090 1998757..2000031 - 1275 WP_156931823.1 nickel-dependent lactate racemase -
B7L28_RS09095 2000443..2001987 - 1545 WP_156931825.1 ClC family H(+)/Cl(-) exchange transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(7-94)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-86)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11065.00 Da        Isoelectric Point: 9.7449

>T75141 WP_208604724.1 NZ_CP020566:1997326-1997610 [Veillonella atypica]
MLKMKLKIIASNAFKKDLKSAKKRGLKLDKLQSIVDKLADEIPLEQKYRDHALTGNYKDFRECHIEPDWLLIYRKDADVL
ELFLFRTGTHADLF

Download         Length: 285 bp

>T75141 NZ_CP020566:1997326-1997610 [Veillonella atypica]
ATGTTGAAAATGAAACTTAAGATTATTGCATCAAATGCTTTCAAAAAAGATTTAAAATCTGCTAAAAAACGTGGCTTAAA
ACTAGATAAATTACAATCTATCGTAGATAAACTCGCCGATGAAATCCCCTTAGAACAAAAGTATCGTGACCACGCACTTA
CAGGAAACTATAAAGATTTTCGAGAATGTCATATAGAACCAGATTGGCTATTAATTTATCGAAAAGATGCAGATGTTCTT
GAGTTATTTCTATTCCGAACCGGAACACACGCAGATTTATTCTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10509.97 Da        Isoelectric Point: 5.1473

>AT75141 WP_156931817.1 NZ_CP020566:1997064-1997345 [Veillonella atypica]
MATTNINVRVDELLKKDAEALFNDLGLSMSSAITMFLKSALSHDGIPFEVKRAKPNTDTIQALAEYETMKAHPEKYKRYS
NFAELLKDVENET

Download         Length: 282 bp

>AT75141 NZ_CP020566:1997064-1997345 [Veillonella atypica]
ATGGCTACAACTAATATCAATGTACGAGTTGACGAATTATTGAAAAAAGATGCTGAAGCATTGTTTAATGACTTAGGCCT
CAGCATGTCATCTGCCATCACTATGTTCTTAAAATCTGCATTAAGTCATGATGGTATCCCCTTCGAAGTAAAACGTGCTA
AACCAAATACAGACACAATACAAGCATTAGCAGAATATGAAACTATGAAAGCTCATCCAGAAAAATACAAACGTTATAGT
AATTTTGCAGAATTACTTAAGGATGTTGAAAATGAAACTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References