Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 465032..465509 Replicon chromosome
Accession NZ_CP020566
Organism Veillonella atypica strain OK5

Toxin (Protein)


Gene name relE Uniprot ID A0A2S7ZS46
Locus tag B7L28_RS02065 Protein ID WP_038124768.1
Coordinates 465243..465509 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S3ASK6
Locus tag B7L28_RS02060 Protein ID WP_016475958.1
Coordinates 465032..465253 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7L28_RS02025 460354..460971 - 618 WP_060807543.1 DUF2939 domain-containing protein -
B7L28_RS02030 461119..462333 + 1215 WP_156931002.1 inverse autotransporter beta domain-containing protein -
B7L28_RS02050 462973..464400 + 1428 WP_156931003.1 hypothetical protein -
B7L28_RS02055 464823..464969 + 147 WP_156931004.1 ESPR domain-containing protein -
B7L28_RS02060 465032..465253 + 222 WP_016475958.1 hypothetical protein Antitoxin
B7L28_RS02065 465243..465509 + 267 WP_038124768.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
B7L28_RS02070 465521..465733 + 213 WP_009661003.1 hypothetical protein -
B7L28_RS02075 465776..466567 - 792 WP_156931005.1 carbon-nitrogen family hydrolase -
B7L28_RS02080 466744..467550 + 807 WP_005380216.1 polysaccharide deacetylase family protein -
B7L28_RS02085 467562..468500 + 939 WP_005377648.1 phosphodiester glycosidase family protein -
B7L28_RS02090 468509..469450 + 942 WP_005377691.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-85)

Antitoxin

Protein of unknown function DUF6290

(1-69)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10606.26 Da        Isoelectric Point: 10.4520

>T75140 WP_038124768.1 NZ_CP020566:465243-465509 [Veillonella atypica]
MVYKLEFSKRFDRQFSKLDKSTQRYIFNWLIKHLDNVENPRYSGKSLTGNKQGLWRYRIGNYRVIVDISDTNCVIIAVEV
GHRKFIYK

Download         Length: 267 bp

>T75140 NZ_CP020566:465243-465509 [Veillonella atypica]
ATGGTTTATAAGCTAGAGTTTAGTAAACGGTTTGACCGACAATTTTCAAAGTTGGATAAGTCAACACAACGTTATATTTT
TAATTGGTTGATAAAACATTTGGATAATGTAGAAAATCCACGATATTCTGGTAAATCGTTAACTGGTAATAAACAAGGAT
TGTGGCGGTATAGAATTGGCAACTATAGAGTTATTGTTGACATTAGTGATACGAATTGTGTGATTATAGCGGTAGAAGTA
GGTCATCGAAAATTTATTTATAAGTAG

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8558.73 Da        Isoelectric Point: 4.4633

>AT75140 WP_016475958.1 NZ_CP020566:465032-465253 [Veillonella atypica]
MSNISVRLNEQEETLFKTYAEFMDETLSTLFKKALLEKIENDFDLRVGQEALKEYKQDPVTYSVAEMRAKYGL

Download         Length: 222 bp

>AT75140 NZ_CP020566:465032-465253 [Veillonella atypica]
ATGTCAAATATTTCTGTGAGACTTAATGAACAAGAAGAAACACTGTTTAAAACTTATGCGGAATTTATGGATGAAACCTT
GTCAACACTATTTAAAAAAGCTTTACTAGAAAAAATCGAAAATGACTTTGATCTTAGGGTGGGTCAAGAAGCTTTGAAAG
AATATAAACAGGATCCTGTTACATATTCTGTAGCAGAAATGCGTGCAAAGTATGGTTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2S7ZS46

Antitoxin

Source ID Structure
AlphaFold DB A0A2S7ZS26

References