Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 692559..693061 Replicon chromosome
Accession NZ_CP020562
Organism Halomonas sp. GT

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag B6A39_RS03265 Protein ID WP_083001310.1
Coordinates 692559..692813 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag B6A39_RS03270 Protein ID WP_083001312.1
Coordinates 692810..693061 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B6A39_RS03235 687874..689103 + 1230 WP_083001302.1 hypothetical protein -
B6A39_RS03240 689100..689966 + 867 WP_083001304.1 hypothetical protein -
B6A39_RS18865 690284..690421 + 138 WP_156886190.1 hypothetical protein -
B6A39_RS03245 690649..690921 + 273 WP_083001306.1 ribbon-helix-helix protein, CopG family -
B6A39_RS03250 690918..691199 + 282 WP_083001308.1 type II toxin-antitoxin system RelE/ParE family toxin -
B6A39_RS03255 691352..691535 + 184 Protein_633 type II toxin-antitoxin system YoeB family toxin -
B6A39_RS03260 691582..692543 + 962 Protein_634 ribonuclease Z -
B6A39_RS03265 692559..692813 - 255 WP_083001310.1 Txe/YoeB family addiction module toxin Toxin
B6A39_RS03270 692810..693061 - 252 WP_083001312.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
B6A39_RS03275 693225..694421 - 1197 WP_083001314.1 homoserine O-acetyltransferase -
B6A39_RS03280 694499..695671 - 1173 WP_083001316.1 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase -
B6A39_RS03285 695787..696626 + 840 WP_156886191.1 NAD-dependent protein deacetylase -
B6A39_RS03290 696623..697264 - 642 WP_083001321.1 DNA-3-methyladenine glycosylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10102.71 Da        Isoelectric Point: 9.8352

>T75137 WP_083001310.1 NZ_CP020562:c692813-692559 [Halomonas sp. GT]
MKLIFAEHAWEDYLYWQKTDKKVLGRINKLIKETQREPFGGVGKPEPLKHGLAGYWSRRINEEHRMIYKVTDDALLIAQL
RYHY

Download         Length: 255 bp

>T75137 NZ_CP020562:c692813-692559 [Halomonas sp. GT]
ATGAAACTCATCTTCGCTGAGCATGCATGGGAAGATTATTTATACTGGCAAAAAACGGACAAAAAAGTGCTTGGCCGTAT
CAATAAGCTAATCAAAGAAACCCAACGAGAACCCTTTGGCGGCGTTGGTAAACCAGAGCCTCTTAAACACGGCTTGGCCG
GTTACTGGTCTCGACGCATCAACGAAGAGCACCGGATGATTTACAAGGTGACTGACGATGCGCTGCTGATCGCCCAGCTT
CGGTATCACTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9295.56 Da        Isoelectric Point: 4.4284

>AT75137 WP_083001312.1 NZ_CP020562:c693061-692810 [Halomonas sp. GT]
MDAISYTAARTNLAKTMQQVCEDHAPMIITRNKAQSVVMVSLEDYEALQETAYLLRAPKNAQRLLESIAELEQGGGQERE
LLE

Download         Length: 252 bp

>AT75137 NZ_CP020562:c693061-692810 [Halomonas sp. GT]
ATGGATGCCATTAGCTACACAGCAGCTAGAACCAATCTAGCGAAAACAATGCAACAGGTCTGCGAAGATCACGCGCCCAT
GATCATTACCCGTAACAAAGCGCAGTCTGTGGTCATGGTCTCTTTAGAGGATTATGAGGCACTGCAAGAGACCGCCTACC
TGCTGCGCGCCCCCAAGAATGCTCAACGCTTGCTTGAGTCAATTGCCGAGCTAGAGCAAGGTGGCGGCCAAGAGCGGGAA
CTCTTGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References