Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/- |
Location | 3286302..3287523 | Replicon | chromosome |
Accession | NZ_CP020560 | ||
Organism | Pseudomonas aeruginosa strain CR1 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | B7D75_RS15530 | Protein ID | WP_107114198.1 |
Coordinates | 3286945..3287523 (+) | Length | 193 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | B7D75_RS15525 | Protein ID | WP_034082653.1 |
Coordinates | 3286302..3286856 (+) | Length | 185 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
B7D75_RS15500 | 3281871..3282422 | + | 552 | WP_107114196.1 | XRE family transcriptional regulator | - |
B7D75_RS15505 | 3282419..3282817 | - | 399 | WP_033997206.1 | NADH-quinone oxidoreductase subunit A | - |
B7D75_RS15510 | 3282830..3283153 | - | 324 | WP_012076113.1 | quaternary ammonium compound efflux SMR transporter SugE | - |
B7D75_RS15515 | 3283483..3283944 | + | 462 | WP_012076114.1 | (2Fe-2S)-binding protein | - |
B7D75_RS15520 | 3283949..3286144 | + | 2196 | WP_107114197.1 | xanthine dehydrogenase family protein molybdopterin-binding subunit | - |
B7D75_RS15525 | 3286302..3286856 | + | 555 | WP_034082653.1 | helix-turn-helix domain-containing protein | Antitoxin |
B7D75_RS15530 | 3286945..3287523 | + | 579 | WP_107114198.1 | HD domain-containing protein | Toxin |
B7D75_RS15535 | 3287629..3288816 | - | 1188 | WP_012076116.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
B7D75_RS15540 | 3288806..3290977 | - | 2172 | WP_043104503.1 | type I secretion system permease/ATPase | - |
B7D75_RS15545 | 3290967..3292244 | - | 1278 | WP_003153546.1 | TolC family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 193 a.a. Molecular weight: 21811.66 Da Isoelectric Point: 5.3655
>T75133 WP_107114198.1 NZ_CP020560:3286945-3287523 [Pseudomonas aeruginosa]
MSLELLKNRLDFLSEAERLKDVLRSAHTSSGRPESTAEHSWRLCLMALAFEDQLAGLDLGKVLRMCVVHDLGEAIHGDIP
AVEQAAHPDKGEQERADLLQLTRHLDAPLRERLLALWDEYERGESAEALAVKALDKLETLLQHTQGDNPADFDYAFNLDY
GRRYTDRAPLFKALRELLDARTRQRLAARRDA
MSLELLKNRLDFLSEAERLKDVLRSAHTSSGRPESTAEHSWRLCLMALAFEDQLAGLDLGKVLRMCVVHDLGEAIHGDIP
AVEQAAHPDKGEQERADLLQLTRHLDAPLRERLLALWDEYERGESAEALAVKALDKLETLLQHTQGDNPADFDYAFNLDY
GRRYTDRAPLFKALRELLDARTRQRLAARRDA
Download Length: 579 bp
>T75133 NZ_CP020560:3286945-3287523 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAAGAACCGCCTCGACTTCCTCAGCGAAGCCGAACGCCTGAAAGATGTCCTGCGCTCCGCGCA
TACGTCTTCCGGTCGCCCGGAAAGCACCGCCGAACACAGTTGGCGGCTGTGCCTGATGGCGCTGGCCTTCGAGGATCAAC
TGGCCGGCCTGGACCTCGGCAAGGTCCTACGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCG
GCCGTCGAGCAGGCCGCGCACCCGGACAAGGGCGAACAGGAACGCGCCGACCTGTTGCAGTTGACTCGTCACCTCGACGC
GCCGCTGCGCGAACGCCTGCTCGCCCTGTGGGATGAATACGAGCGCGGCGAGTCCGCCGAAGCCCTGGCAGTGAAGGCCC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGGCCCTGCGCGAGCTACTCGACGCCAGGACCCGACAGCGCCTCGC
GGCTCGGCGCGACGCCTAG
ATGTCCCTCGAACTGCTGAAGAACCGCCTCGACTTCCTCAGCGAAGCCGAACGCCTGAAAGATGTCCTGCGCTCCGCGCA
TACGTCTTCCGGTCGCCCGGAAAGCACCGCCGAACACAGTTGGCGGCTGTGCCTGATGGCGCTGGCCTTCGAGGATCAAC
TGGCCGGCCTGGACCTCGGCAAGGTCCTACGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCG
GCCGTCGAGCAGGCCGCGCACCCGGACAAGGGCGAACAGGAACGCGCCGACCTGTTGCAGTTGACTCGTCACCTCGACGC
GCCGCTGCGCGAACGCCTGCTCGCCCTGTGGGATGAATACGAGCGCGGCGAGTCCGCCGAAGCCCTGGCAGTGAAGGCCC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGGCCCTGCGCGAGCTACTCGACGCCAGGACCCGACAGCGCCTCGC
GGCTCGGCGCGACGCCTAG
Antitoxin
Download Length: 185 a.a. Molecular weight: 20379.48 Da Isoelectric Point: 8.9546
>AT75133 WP_034082653.1 NZ_CP020560:3286302-3286856 [Pseudomonas aeruginosa]
MTEPLPSSSLGPALRRWRLLHRVKQAHAAELFGVAQSTISRWESGAQALRAEERTRLETLLGARLETAADRALARLVDGS
PQPMHLICDLTHRLLACSPARAAQFAVPLGDLLGRSLWPYCSEEILRQEAALDDLGWRELLAPPALEFASGTNASTIVPI
RRSRCRWTRLTLSDGRAVRLVETL
MTEPLPSSSLGPALRRWRLLHRVKQAHAAELFGVAQSTISRWESGAQALRAEERTRLETLLGARLETAADRALARLVDGS
PQPMHLICDLTHRLLACSPARAAQFAVPLGDLLGRSLWPYCSEEILRQEAALDDLGWRELLAPPALEFASGTNASTIVPI
RRSRCRWTRLTLSDGRAVRLVETL
Download Length: 555 bp
>AT75133 NZ_CP020560:3286302-3286856 [Pseudomonas aeruginosa]
ATGACCGAGCCTCTTCCTTCTTCGTCCCTGGGCCCCGCCCTGCGCCGTTGGCGCCTGCTGCACCGGGTCAAGCAGGCGCA
CGCCGCCGAGCTGTTCGGCGTGGCCCAGTCGACCATCTCGCGCTGGGAATCCGGCGCCCAGGCGCTGCGAGCGGAGGAAC
GGACGCGCCTGGAAACCCTCCTCGGCGCCCGCCTGGAGACCGCCGCCGACCGGGCGCTGGCCCGCCTGGTCGATGGCAGC
CCGCAGCCGATGCATCTGATCTGCGACCTCACCCACCGCCTGCTGGCCTGCTCGCCGGCGCGCGCCGCGCAATTCGCCGT
CCCCCTCGGCGACCTGCTCGGCCGTTCGCTGTGGCCGTATTGCAGCGAGGAGATCCTCCGCCAGGAAGCCGCCCTCGACG
ACCTCGGCTGGCGCGAGCTGCTGGCGCCGCCGGCGCTGGAGTTCGCCAGCGGAACGAACGCCTCGACCATCGTGCCGATC
CGGCGCAGCCGCTGCCGCTGGACCCGCCTGACGCTCTCCGACGGCCGCGCGGTGCGGCTGGTGGAAACCCTCTGA
ATGACCGAGCCTCTTCCTTCTTCGTCCCTGGGCCCCGCCCTGCGCCGTTGGCGCCTGCTGCACCGGGTCAAGCAGGCGCA
CGCCGCCGAGCTGTTCGGCGTGGCCCAGTCGACCATCTCGCGCTGGGAATCCGGCGCCCAGGCGCTGCGAGCGGAGGAAC
GGACGCGCCTGGAAACCCTCCTCGGCGCCCGCCTGGAGACCGCCGCCGACCGGGCGCTGGCCCGCCTGGTCGATGGCAGC
CCGCAGCCGATGCATCTGATCTGCGACCTCACCCACCGCCTGCTGGCCTGCTCGCCGGCGCGCGCCGCGCAATTCGCCGT
CCCCCTCGGCGACCTGCTCGGCCGTTCGCTGTGGCCGTATTGCAGCGAGGAGATCCTCCGCCAGGAAGCCGCCCTCGACG
ACCTCGGCTGGCGCGAGCTGCTGGCGCCGCCGGCGCTGGAGTTCGCCAGCGGAACGAACGCCTCGACCATCGTGCCGATC
CGGCGCAGCCGCTGCCGCTGGACCCGCCTGACGCTCTCCGACGGCCGCGCGGTGCGGCTGGTGGAAACCCTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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