75132

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 1799344..1800852 Replicon chromosome
Accession NZ_CP020560
Organism Pseudomonas aeruginosa strain CR1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag B7D75_RS08620 Protein ID WP_079383582.1
Coordinates 1799344..1799931 (+) Length 196 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag B7D75_RS08625 Protein ID WP_107113921.1
Coordinates 1799998..1800852 (+) Length 285 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7D75_RS08615 1795599..1799078 - 3480 WP_012074951.1 hybrid sensor histidine kinase/response regulator -
B7D75_RS08620 1799344..1799931 + 588 WP_079383582.1 GNAT family N-acetyltransferase Toxin
B7D75_RS08625 1799998..1800852 + 855 WP_107113921.1 AraC family transcriptional regulator Antitoxin
B7D75_RS08630 1800948..1803113 + 2166 WP_107113922.1 TonB-dependent receptor family protein -
B7D75_RS08635 1803288..1805162 + 1875 WP_043100745.1 MFS transporter -
B7D75_RS08640 1805223..1805432 - 210 WP_003091604.1 cold-shock protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(20-152)

Antitoxin

AraC-type arabinose-binding/dimerisation domain

(19-147)


Sequences

Toxin        


Download         Length: 196 a.a.        Molecular weight: 21862.19 Da        Isoelectric Point: 9.8675

>T75132 WP_079383582.1 NZ_CP020560:1799344-1799931 [Pseudomonas aeruginosa]
MSRRAPMFKPLPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQGIADQREGRALPLAVRLGVQLV
GTTRFAEFLPALPACEIGWTWLDQAQHGSGLNRMIKYLMLKHAFDNLRMVRVQFSTAASNLRAQGAIDKLGAQREGLLRN
QRRLAGGRLDDTIVYSITDHEWPQVKAALEASFTG

Download         Length: 588 bp

>T75132 NZ_CP020560:1799344-1799931 [Pseudomonas aeruginosa]
ATGTCGAGGAGGGCGCCCATGTTCAAGCCGCTACCGATCACCCTGCAGCGTGGAGCCTTGCGGCTCGAGCCGCTGGTGGA
AGCGGACATTCCCGAGCTGGTGAGCCTTGCCGAAGCCAACCGCGAGGCACTGCAGTACATGGACGGACCGACGCGCCCGG
ACTGGTATCGCCAGGGCATCGCTGACCAGCGCGAGGGACGCGCGTTGCCGCTGGCGGTACGCCTGGGCGTGCAACTGGTC
GGGACCACGCGCTTCGCCGAATTCCTTCCCGCCCTGCCGGCCTGCGAGATCGGCTGGACCTGGCTCGACCAGGCCCAGCA
CGGCAGCGGCCTGAACCGCATGATCAAGTACCTGATGCTCAAGCATGCCTTCGACAACCTGCGCATGGTCCGCGTGCAGT
TCAGCACGGCGGCGAGCAACCTGCGCGCCCAGGGCGCCATCGACAAGCTCGGCGCCCAGCGCGAGGGCCTGCTGCGCAAC
CAGCGGCGCCTGGCCGGCGGGCGTCTCGACGACACCATCGTCTACAGCATCACCGACCACGAGTGGCCCCAGGTCAAGGC
CGCGCTGGAAGCCAGCTTCACCGGCTGA

Antitoxin


Download         Length: 285 a.a.        Molecular weight: 31742.08 Da        Isoelectric Point: 7.9939

>AT75132 WP_107113921.1 NZ_CP020560:1799998-1800852 [Pseudomonas aeruginosa]
VPDETSGEHTHFWRAAALGGVELLHARYVEQRFAPHVHSGFALVFIEQGAQRFRHRGGEHLAPWGSMVLINPDEVHTGSK
AHDSGWLYRGYYPEVEQIASVLDELEIRHGGVPRFADSVVHDQPLARAFVYLHRLLADHAGSLETQTCWRETLLALFRRH
ARLPEAPKAGSEPLAVARARELLAARLLDPPSLEELAAAVNLSPFHFARVFRRATGMPPHAWLRQRRLEQARALLKNGRA
PLDVALELGFADQSHLGRQFKQAYGVAPGEYRAACARSSLTMCE

Download         Length: 855 bp

>AT75132 NZ_CP020560:1799998-1800852 [Pseudomonas aeruginosa]
GTGCCGGACGAGACGAGCGGAGAACATACGCATTTCTGGCGCGCCGCCGCACTGGGCGGCGTCGAGTTGCTGCATGCGCG
CTACGTCGAGCAGCGTTTCGCCCCCCATGTGCACAGCGGCTTCGCCCTGGTCTTCATCGAGCAGGGCGCGCAGCGCTTCC
GCCATCGCGGCGGCGAGCACCTGGCGCCCTGGGGCAGCATGGTGCTGATCAACCCCGACGAAGTGCATACCGGCTCCAAG
GCCCATGACTCCGGCTGGCTCTATCGCGGCTACTACCCGGAAGTGGAGCAGATCGCCAGTGTCCTCGACGAGCTGGAAAT
CCGCCACGGCGGGGTGCCGCGTTTCGCCGACAGCGTGGTCCACGACCAGCCCCTGGCGCGCGCCTTCGTCTATCTGCACC
GCTTACTGGCCGACCACGCCGGCAGCCTGGAAACCCAGACCTGCTGGCGCGAGACGCTGCTCGCCCTGTTCCGTCGCCAC
GCCCGCCTGCCGGAGGCGCCGAAGGCCGGGTCGGAACCGCTGGCGGTCGCCCGCGCCCGCGAGTTGCTGGCGGCGCGTTT
GCTCGACCCGCCGTCGCTGGAAGAACTGGCGGCTGCGGTGAACCTGTCGCCGTTCCACTTCGCCCGGGTGTTCCGCCGCG
CCACCGGGATGCCGCCGCATGCCTGGCTCCGGCAACGGCGCCTGGAGCAGGCCAGGGCGCTGCTCAAGAATGGCCGGGCG
CCGCTGGATGTCGCCCTGGAACTGGGCTTCGCCGACCAGAGCCATCTCGGTCGCCAGTTCAAGCAGGCCTACGGCGTGGC
GCCGGGCGAGTACCGCGCGGCCTGTGCGCGCTCGTCCTTGACGATGTGCGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References