Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 4923949..4924478 Replicon chromosome
Accession NZ_CP020555
Organism Streptomyces sp. Sge12

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag B6R96_RS22000 Protein ID WP_081523370.1
Coordinates 4923949..4924206 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag B6R96_RS22005 Protein ID WP_081523372.1
Coordinates 4924203..4924478 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B6R96_RS21970 4919552..4919746 - 195 WP_030388650.1 hypothetical protein -
B6R96_RS21975 4919983..4920672 + 690 WP_030388651.1 cell division ATP-binding protein FtsE -
B6R96_RS21980 4920690..4921658 + 969 WP_030388652.1 permease-like cell division protein FtsX -
B6R96_RS21985 4921726..4922916 + 1191 WP_081523368.1 S41 family peptidase -
B6R96_RS21990 4922935..4923420 + 486 WP_030388654.1 SsrA-binding protein SmpB -
B6R96_RS22000 4923949..4924206 - 258 WP_081523370.1 Txe/YoeB family addiction module toxin Toxin
B6R96_RS22005 4924203..4924478 - 276 WP_081523372.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
B6R96_RS22010 4924516..4925766 - 1251 WP_081525196.1 MFS transporter -
B6R96_RS22015 4925861..4926826 + 966 WP_037861036.1 LysR family transcriptional regulator -
B6R96_RS22020 4926923..4928293 + 1371 WP_053702260.1 NarK/NasA family nitrate transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-71)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10205.64 Da        Isoelectric Point: 9.8313

>T75126 WP_081523370.1 NZ_CP020555:c4924206-4923949 [Streptomyces sp. Sge12]
VRSVHFDPAAWEDFLFWLSSDRKMARRITRLIGEIQRDPFTGIGKPEPLKGELTGYWSRRIDDEHRLVYRADDKEVKVLK
ARYHY

Download         Length: 258 bp

>T75126 NZ_CP020555:c4924206-4923949 [Streptomyces sp. Sge12]
GTGAGGAGCGTTCACTTCGACCCCGCCGCCTGGGAGGACTTCCTGTTCTGGTTGTCGTCGGACCGGAAGATGGCCCGCCG
GATCACTCGCCTGATCGGCGAGATCCAGCGCGACCCGTTCACCGGCATCGGCAAGCCCGAGCCGTTGAAGGGCGAGTTGA
CCGGCTACTGGTCCCGCCGCATCGACGACGAGCACCGCCTCGTGTACCGGGCCGACGACAAGGAAGTGAAGGTCCTCAAG
GCCCGCTACCACTACTGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9939.05 Da        Isoelectric Point: 4.3766

>AT75126 WP_081523372.1 NZ_CP020555:c4924478-4924203 [Streptomyces sp. Sge12]
MSISASEARATLFPLIERVNTDHAPVRITSKSGDAVLMSADDYDSWQETVYLLRSPANAQRLMEAVARDREGASTVARTV
DELKELAGGEE

Download         Length: 276 bp

>AT75126 NZ_CP020555:c4924478-4924203 [Streptomyces sp. Sge12]
ATGTCCATAAGCGCCAGCGAAGCCAGGGCCACCCTGTTCCCGCTGATCGAGCGTGTCAACACCGACCACGCCCCGGTGCG
CATCACCTCCAAGAGCGGTGACGCGGTCCTCATGTCCGCCGACGACTACGACTCCTGGCAGGAGACCGTCTACCTCCTGC
GCTCCCCCGCCAACGCCCAGCGTTTGATGGAGGCCGTCGCGCGCGACCGCGAGGGCGCCTCCACGGTCGCGAGGACGGTG
GACGAGCTGAAGGAGTTGGCCGGGGGCGAGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References