Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relE-dinJ/YafQ-RelB |
Location | 702099..702630 | Replicon | plasmid pMSHV |
Accession | NZ_CP020539 | ||
Organism | Sphingobium herbicidovorans strain MH |
Toxin (Protein)
Gene name | relE | Uniprot ID | T0GNF5 |
Locus tag | B6S01_RS17970 | Protein ID | WP_004212690.1 |
Coordinates | 702099..702380 (-) | Length | 94 a.a. |
Antitoxin (Protein)
Gene name | dinJ | Uniprot ID | T0G968 |
Locus tag | B6S01_RS17975 | Protein ID | WP_004212689.1 |
Coordinates | 702367..702630 (-) | Length | 88 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
B6S01_RS17955 | 699658..700086 | - | 429 | WP_021245211.1 | TonB-dependent receptor | - |
B6S01_RS17960 | 700288..701016 | - | 729 | WP_025549137.1 | IS21-like element helper ATPase IstB | - |
B6S01_RS17965 | 701003..701697 | - | 695 | Protein_687 | IS21 family transposase | - |
B6S01_RS21435 | 701695..701778 | - | 84 | Protein_688 | magnesium transporter | - |
B6S01_RS17970 | 702099..702380 | - | 282 | WP_004212690.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
B6S01_RS17975 | 702367..702630 | - | 264 | WP_004212689.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
B6S01_RS17980 | 703014..703451 | - | 438 | WP_007683347.1 | metal-binding protein | - |
B6S01_RS17985 | 703531..704772 | - | 1242 | WP_007683345.1 | MFS transporter | - |
B6S01_RS17990 | 704766..705752 | - | 987 | WP_004212678.1 | copper resistance protein B | - |
B6S01_RS17995 | 705749..707455 | - | 1707 | WP_021238859.1 | copper resistance system multicopper oxidase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..959196 | 959196 | |
- | flank | IS/Tn | - | - | 700288..701016 | 728 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10993.49 Da Isoelectric Point: 7.4752
>T75053 WP_004212690.1 NZ_CP020539:c702380-702099 [Sphingobium herbicidovorans]
MRTIERFGRFKRDYKREKKGQHAKTLDADLIPIIEALASDEPLEPRHRDHALTGDWRDHRDCHIKPDLVLIYRKPDDDTL
QLVRLGSHAELGW
MRTIERFGRFKRDYKREKKGQHAKTLDADLIPIIEALASDEPLEPRHRDHALTGDWRDHRDCHIKPDLVLIYRKPDDDTL
QLVRLGSHAELGW
Download Length: 282 bp
>T75053 NZ_CP020539:c702380-702099 [Sphingobium herbicidovorans]
ATGCGGACGATTGAACGCTTCGGGCGGTTCAAGCGCGACTACAAGCGGGAGAAGAAGGGGCAGCACGCCAAGACGCTGGA
CGCTGACCTGATCCCGATCATCGAGGCGCTGGCATCCGACGAGCCGCTTGAACCGCGCCACCGCGACCATGCGCTGACCG
GCGACTGGCGCGACCATCGCGATTGCCACATAAAGCCCGACCTCGTGCTGATTTACCGCAAGCCCGATGACGACACCTTG
CAGCTTGTGCGCTTGGGATCGCACGCGGAATTGGGTTGGTGA
ATGCGGACGATTGAACGCTTCGGGCGGTTCAAGCGCGACTACAAGCGGGAGAAGAAGGGGCAGCACGCCAAGACGCTGGA
CGCTGACCTGATCCCGATCATCGAGGCGCTGGCATCCGACGAGCCGCTTGAACCGCGCCACCGCGACCATGCGCTGACCG
GCGACTGGCGCGACCATCGCGATTGCCACATAAAGCCCGACCTCGTGCTGATTTACCGCAAGCCCGATGACGACACCTTG
CAGCTTGTGCGCTTGGGATCGCACGCGGAATTGGGTTGGTGA
Antitoxin
Download Length: 88 a.a. Molecular weight: 9284.75 Da Isoelectric Point: 4.5881
>AT75053 WP_004212689.1 NZ_CP020539:c702630-702367 [Sphingobium herbicidovorans]
MAANALVQTRIDGAVKEEAATVLAAMGLTVSDAVRLMLTRVARDKALPFEPLVPNAETIEAMKEAREGKGKRFATVVDLM
ADLNADD
MAANALVQTRIDGAVKEEAATVLAAMGLTVSDAVRLMLTRVARDKALPFEPLVPNAETIEAMKEAREGKGKRFATVVDLM
ADLNADD
Download Length: 264 bp
>AT75053 NZ_CP020539:c702630-702367 [Sphingobium herbicidovorans]
ATGGCCGCAAACGCTCTTGTGCAGACCCGGATCGACGGAGCGGTGAAGGAGGAAGCCGCGACCGTGCTGGCTGCTATGGG
GCTGACCGTCTCCGATGCCGTGCGCCTGATGCTGACCCGCGTTGCCCGCGACAAGGCCTTGCCGTTTGAACCGCTGGTGC
CCAATGCCGAGACGATCGAGGCCATGAAGGAAGCGCGCGAGGGAAAGGGCAAGCGGTTCGCCACGGTGGTCGACCTGATG
GCCGACCTCAATGCGGACGATTGA
ATGGCCGCAAACGCTCTTGTGCAGACCCGGATCGACGGAGCGGTGAAGGAGGAAGCCGCGACCGTGCTGGCTGCTATGGG
GCTGACCGTCTCCGATGCCGTGCGCCTGATGCTGACCCGCGTTGCCCGCGACAAGGCCTTGCCGTTTGAACCGCTGGTGC
CCAATGCCGAGACGATCGAGGCCATGAAGGAAGCGCGCGAGGGAAAGGGCAAGCGGTTCGCCACGGTGGTCGACCTGATG
GCCGACCTCAATGCGGACGATTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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