Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /DUF1778(antitoxin) |
| Location | 21645..22606 | Replicon | chromosome |
| Accession | NZ_CP020533 | ||
| Organism | Vibrio anguillarum strain 425 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | F7YRB7 |
| Locus tag | B5S57_RS00425 | Protein ID | WP_013868567.1 |
| Coordinates | 22073..22606 (+) | Length | 178 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | B5S57_RS20480 | Protein ID | WP_013868568.1 |
| Coordinates | 21645..22076 (+) | Length | 144 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| B5S57_RS00385 | 17067..18500 | - | 1434 | Protein_14 | DEAD/DEAH box helicase family protein | - |
| B5S57_RS00390 | 19042..19356 | + | 315 | WP_006073510.1 | hypothetical protein | - |
| B5S57_RS00395 | 19398..20366 | - | 969 | WP_076611895.1 | IS30-like element ISVa6 family transposase | - |
| B5S57_RS00400 | 20481..20573 | + | 93 | WP_072600976.1 | DUF3265 domain-containing protein | - |
| B5S57_RS00405 | 20611..21126 | + | 516 | WP_013868571.1 | GNAT family N-acetyltransferase | - |
| B5S57_RS20480 | 21645..22076 | + | 432 | WP_013868568.1 | DUF1778 domain-containing protein | Antitoxin |
| B5S57_RS00425 | 22073..22606 | + | 534 | WP_013868567.1 | GNAT family N-acetyltransferase | Toxin |
| B5S57_RS00435 | 23292..23573 | + | 282 | WP_029190024.1 | hypothetical protein | - |
| B5S57_RS00445 | 24081..24206 | + | 126 | WP_013868562.1 | DUF3265 domain-containing protein | - |
| B5S57_RS00450 | 24260..24808 | + | 549 | WP_019281391.1 | hypothetical protein | - |
| B5S57_RS00455 | 24959..25303 | + | 345 | WP_013868560.1 | hypothetical protein | - |
| B5S57_RS00460 | 25300..25416 | + | 117 | WP_080749045.1 | DUF3265 domain-containing protein | - |
| B5S57_RS00465 | 25456..26112 | + | 657 | WP_013868559.1 | hypothetical protein | - |
| B5S57_RS00470 | 26270..26587 | + | 318 | WP_011154648.1 | IS66 family insertion sequence hypothetical protein | - |
| B5S57_RS00475 | 26584..26937 | + | 354 | WP_011154649.1 | IS66 family insertion sequence element accessory protein TnpB | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integron | - | - | 19398..26112 | 6714 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 178 a.a. Molecular weight: 20222.47 Da Isoelectric Point: 9.1188
>T75047 WP_013868567.1 NZ_CP020533:22073-22606 [Vibrio anguillarum]
VSWGREFVELSKSKHDRDSFDCGEQELNTFIKTQAAKHMQAGISRTMVLPSGQPLLNQKFAICAFYSVAPSSISRETLPT
QLAKKLPRYPIPVFLLAQLAVHKEFHGSGLGKVSLIRALKYLWEVNHHMRAYAIVVDCLTDSAQAFYTKFGFEVLCEHNE
RIRMYLPMKTVEQLFNQ
VSWGREFVELSKSKHDRDSFDCGEQELNTFIKTQAAKHMQAGISRTMVLPSGQPLLNQKFAICAFYSVAPSSISRETLPT
QLAKKLPRYPIPVFLLAQLAVHKEFHGSGLGKVSLIRALKYLWEVNHHMRAYAIVVDCLTDSAQAFYTKFGFEVLCEHNE
RIRMYLPMKTVEQLFNQ
Download Length: 534 bp
>T75047 NZ_CP020533:22073-22606 [Vibrio anguillarum]
GTGAGTTGGGGCAGAGAGTTTGTAGAACTTAGTAAATCAAAGCATGACCGCGACTCATTTGACTGTGGTGAGCAAGAGCT
AAACACATTTATCAAAACTCAAGCTGCAAAGCACATGCAAGCAGGTATTAGCCGAACAATGGTTTTACCTAGTGGTCAAC
CGCTGTTAAATCAAAAATTCGCTATTTGTGCCTTTTATAGTGTTGCACCGAGCTCAATCAGCCGAGAAACATTACCGACA
CAGTTAGCAAAGAAACTACCGAGATATCCAATCCCTGTTTTTCTGTTGGCTCAATTAGCTGTGCACAAAGAATTTCACGG
TTCTGGACTTGGAAAGGTCAGTCTAATTCGTGCGCTGAAGTACTTGTGGGAAGTAAATCATCACATGAGGGCATACGCAA
TAGTTGTGGATTGTCTGACAGATTCCGCTCAAGCGTTCTATACGAAGTTCGGCTTTGAAGTATTGTGCGAACATAATGAG
CGTATTCGTATGTACTTACCGATGAAAACGGTAGAACAGCTTTTTAATCAATAG
GTGAGTTGGGGCAGAGAGTTTGTAGAACTTAGTAAATCAAAGCATGACCGCGACTCATTTGACTGTGGTGAGCAAGAGCT
AAACACATTTATCAAAACTCAAGCTGCAAAGCACATGCAAGCAGGTATTAGCCGAACAATGGTTTTACCTAGTGGTCAAC
CGCTGTTAAATCAAAAATTCGCTATTTGTGCCTTTTATAGTGTTGCACCGAGCTCAATCAGCCGAGAAACATTACCGACA
CAGTTAGCAAAGAAACTACCGAGATATCCAATCCCTGTTTTTCTGTTGGCTCAATTAGCTGTGCACAAAGAATTTCACGG
TTCTGGACTTGGAAAGGTCAGTCTAATTCGTGCGCTGAAGTACTTGTGGGAAGTAAATCATCACATGAGGGCATACGCAA
TAGTTGTGGATTGTCTGACAGATTCCGCTCAAGCGTTCTATACGAAGTTCGGCTTTGAAGTATTGTGCGAACATAATGAG
CGTATTCGTATGTACTTACCGATGAAAACGGTAGAACAGCTTTTTAATCAATAG
Antitoxin
Download Length: 144 a.a. Molecular weight: 15859.40 Da Isoelectric Point: 7.0831
>AT75047 WP_013868568.1 NZ_CP020533:21645-22076 [Vibrio anguillarum]
VFTVCFLSSAVRCQPLSRALYSPSFRKLSVRIECALSLAYNRSTDGMYPYAGGVMATARLDIRLDEEIKAKAEKASALLG
LKSLTEYVVRLMDEDATHVIEEHESIMVKDSVFDEFMAACNKVKAPNQALLEAVKFTEKSGIK
VFTVCFLSSAVRCQPLSRALYSPSFRKLSVRIECALSLAYNRSTDGMYPYAGGVMATARLDIRLDEEIKAKAEKASALLG
LKSLTEYVVRLMDEDATHVIEEHESIMVKDSVFDEFMAACNKVKAPNQALLEAVKFTEKSGIK
Download Length: 432 bp
>AT75047 NZ_CP020533:21645-22076 [Vibrio anguillarum]
GTGTTTACAGTGTGTTTTTTGAGTTCGGCGGTGCGTTGTCAACCCCTTAGCCGGGCGTTATATTCTCCCTCGTTCCGTAA
ACTTTCCGTACGAATTGAATGTGCTTTAAGTTTGGCCTATAATCGCTCAACTGACGGAATGTATCCGTATGCAGGAGGGG
TTATGGCAACGGCACGTTTAGATATCCGCCTTGATGAAGAGATCAAGGCAAAAGCCGAAAAGGCATCGGCTTTACTTGGC
TTAAAAAGTCTCACTGAATACGTGGTGAGACTTATGGACGAAGATGCGACTCATGTTATTGAGGAGCATGAAAGTATTAT
GGTTAAAGACAGTGTTTTTGACGAGTTTATGGCTGCGTGTAATAAAGTAAAAGCACCGAATCAAGCTTTGCTTGAAGCTG
TTAAATTTACAGAGAAGAGCGGTATCAAGTGA
GTGTTTACAGTGTGTTTTTTGAGTTCGGCGGTGCGTTGTCAACCCCTTAGCCGGGCGTTATATTCTCCCTCGTTCCGTAA
ACTTTCCGTACGAATTGAATGTGCTTTAAGTTTGGCCTATAATCGCTCAACTGACGGAATGTATCCGTATGCAGGAGGGG
TTATGGCAACGGCACGTTTAGATATCCGCCTTGATGAAGAGATCAAGGCAAAAGCCGAAAAGGCATCGGCTTTACTTGGC
TTAAAAAGTCTCACTGAATACGTGGTGAGACTTATGGACGAAGATGCGACTCATGTTATTGAGGAGCATGAAAGTATTAT
GGTTAAAGACAGTGTTTTTGACGAGTTTATGGCTGCGTGTAATAAAGTAAAAGCACCGAATCAAGCTTTGCTTGAAGCTG
TTAAATTTACAGAGAAGAGCGGTATCAAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|