Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2965195..2965466 Replicon chromosome
Accession NZ_CP020516
Organism Escherichia coli strain 222

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2965233..2965336 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2965195..2965466 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A9P13_RS15480 2962352..2963791 + 1440 WP_024166480.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
A9P13_RS15485 2963909..2964145 + 237 WP_001295499.1 DUF1480 family protein -
A9P13_RS15490 2964250..2964441 + 192 WP_001296140.1 YebW family protein -
A9P13_RS15495 2964442..2965098 - 657 WP_001520704.1 protein-serine/threonine phosphatase -
- 2965195..2965466 + 272 - - Antitoxin
- 2965233..2965336 - 104 - - Toxin
A9P13_RS15500 2965494..2965835 - 342 WP_001520705.1 YebY family protein -
A9P13_RS15505 2965848..2966720 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
A9P13_RS15510 2966724..2967098 - 375 WP_000204705.1 CopC domain-containing protein YobA -
A9P13_RS15515 2967237..2967467 + 231 WP_000916763.1 DNA polymerase III subunit theta -
A9P13_RS15520 2967569..2968225 + 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
A9P13_RS15525 2968249..2968911 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T74950 NZ_CP020516:c2965336-2965233 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT74950 NZ_CP020516:2965195-2965466 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References