Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2177612..2177883 Replicon chromosome
Accession NZ_CP020509
Organism Escherichia coli strain 165

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2177742..2177845 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2177612..2177883 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AWB10_RS11215 2174167..2174829 - 663 WP_000944256.1 exodeoxyribonuclease X -
AWB10_RS11220 2174853..2175509 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
AWB10_RS11225 2175611..2175841 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AWB10_RS11230 2175980..2176354 + 375 WP_000204699.1 CopC domain-containing protein YobA -
AWB10_RS11235 2176358..2177230 + 873 WP_000879285.1 copper homeostasis membrane protein CopD -
AWB10_RS11240 2177243..2177584 + 342 WP_000976492.1 YebY family protein -
- 2177612..2177883 - 272 - - Antitoxin
- 2177742..2177845 + 104 - - Toxin
AWB10_RS11245 2177980..2178636 + 657 WP_000812734.1 protein-serine/threonine phosphatase -
AWB10_RS11250 2178637..2178828 - 192 WP_001296140.1 YebW family protein -
AWB10_RS11255 2178933..2179169 - 237 WP_001295499.1 DUF1480 family protein -
AWB10_RS11260 2179287..2180726 - 1440 WP_024190454.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T74873 NZ_CP020509:2177742-2177845 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT74873 NZ_CP020509:c2177883-2177612 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References