Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 923325..923983 Replicon chromosome
Accession NZ_CP020503
Organism Serratia marcescens strain 95

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag AM681_RS04395 Protein ID WP_032637385.1
Coordinates 923325..923645 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag AM681_RS04400 Protein ID WP_032637384.1
Coordinates 923666..923983 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM681_RS04375 918376..919914 + 1539 WP_032637388.1 sugar ABC transporter ATP-binding protein -
AM681_RS04380 919917..920999 + 1083 WP_006809988.1 ABC transporter permease -
AM681_RS04385 921088..922038 + 951 WP_048232733.1 D-ribose ABC transporter substrate-binding protein -
AM681_RS04390 922169..923026 + 858 WP_048232736.1 DeoR/GlpR family DNA-binding transcription regulator -
AM681_RS04395 923325..923645 - 321 WP_032637385.1 TA system toxin CbtA family protein Toxin
AM681_RS04400 923666..923983 - 318 WP_032637384.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
AM681_RS04405 924002..924223 - 222 WP_032637383.1 DUF987 domain-containing protein -
AM681_RS04410 924232..924708 - 477 WP_000811693.1 RadC family protein -
AM681_RS04415 924724..925203 - 480 WP_015063037.1 antirestriction protein -
AM681_RS04425 926065..928260 - 2196 WP_048232739.1 DEAD/DEAH box helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-104)

Antitoxin

Antitoxin CbeA

(5-103)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12146.14 Da        Isoelectric Point: 7.1656

>T74822 WP_032637385.1 NZ_CP020503:c923645-923325 [Serratia marcescens]
MKTLPATTLWAAKPCPSPVIVWQMLLSRLLDQHYGLTLNDTPFSDETVIKEHIDAGISLADAVNFLVEKYELVRIDRKGF
SWQEQSPFITAVDILKARRAMREMRT

Download         Length: 321 bp

>T74822 NZ_CP020503:c923645-923325 [Serratia marcescens]
ATGAAAACTCTACCCGCAACGACTTTGTGGGCGGCTAAACCATGCCCGTCACCAGTGATCGTATGGCAAATGCTTCTTTC
ACGTCTGCTGGATCAGCACTATGGCCTGACACTGAATGACACGCCATTCAGTGATGAAACTGTGATTAAGGAACATATCG
ATGCCGGTATCTCTTTAGCCGATGCCGTTAATTTTCTGGTGGAAAAATACGAACTGGTTCGCATCGATCGTAAGGGGTTT
AGCTGGCAAGAACAGTCGCCTTTTATTACTGCTGTAGACATTCTAAAAGCCAGACGGGCTATGAGGGAAATGAGAACATA
A

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12020.58 Da        Isoelectric Point: 6.7389

>AT74822 WP_032637384.1 NZ_CP020503:c923983-923666 [Serratia marcescens]
MSNITWGLQRDITPRLGARLVQEGNRLHYLADRASITGKFSDVECRKLDETFPHFISQMESMLTTDELNPRHAHCVTLYH
NGFTCEADTLGSCGYVYITVYPTHR

Download         Length: 318 bp

>AT74822 NZ_CP020503:c923983-923666 [Serratia marcescens]
ATGAGCAACATTACATGGGGGCTGCAGCGGGATATCACGCCACGCCTGGGAGCCCGTCTGGTGCAGGAGGGGAACCGGCT
GCATTATCTGGCTGACCGGGCCAGCATCACCGGTAAATTCAGTGACGTCGAATGCCGTAAGCTGGATGAAACATTCCCGC
ACTTTATCAGCCAGATGGAGTCGATGCTGACCACCGATGAACTGAATCCCCGCCATGCCCACTGCGTCACCCTGTACCAC
AATGGTTTCACCTGCGAAGCCGACACCCTTGGCAGTTGCGGCTACGTATACATCACCGTTTATCCCACTCACCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References