Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1911647..1911792 Replicon chromosome
Accession NZ_CP020498
Organism Klebsiella pneumoniae strain BWHC1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1911683..1911785 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1911647..1911792 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AA595_RS09615 1906777..1908837 + 2061 WP_032422099.1 oligopeptidase B -
AA595_RS09620 1908841..1909500 - 660 WP_002911407.1 exodeoxyribonuclease X -
AA595_RS09625 1909579..1909809 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AA595_RS09630 1909922..1910296 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AA595_RS09635 1910300..1911169 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
AA595_RS09640 1911186..1911524 + 339 WP_002911404.1 YebY family protein -
- 1911647..1911792 - 146 - - Antitoxin
- 1911683..1911785 + 103 - - Toxin
AA595_RS28235 1912160..1912303 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AA595_RS09650 1912408..1913376 - 969 WP_004151446.1 VirK/YbjX family protein -
AA595_RS09655 1913533..1914186 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
AA595_RS09660 1914183..1914374 - 192 WP_002911395.1 YebW family protein -
AA595_RS09665 1914472..1914711 - 240 WP_002911393.1 YebV family protein -
AA595_RS09670 1914827..1916260 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T74802 NZ_CP020498:1911683-1911785 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT74802 NZ_CP020498:c1911792-1911647 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References