Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-virA/YafQ(toxin)
Location 943716..944274 Replicon chromosome
Accession NZ_CP020478
Organism Campylobacter helveticus strain ATCC 51209

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CHELV3228_RS04950 Protein ID WP_115588761.1
Coordinates 943716..943946 (-) Length 77 a.a.

Antitoxin (Protein)


Gene name virA Uniprot ID -
Locus tag CHELV3228_RS04955 Protein ID WP_082199810.1
Coordinates 943984..944274 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CHELV3228_RS04930 939092..940843 + 1752 WP_082199806.1 aspartate--tRNA ligase -
CHELV3228_RS04935 940840..941415 + 576 WP_082199807.1 adenylate kinase -
CHELV3228_RS04940 941623..941898 + 276 WP_082199808.1 DUF4410 domain-containing protein -
CHELV3228_RS04945 941908..942429 + 522 WP_082199809.1 inorganic diphosphatase -
CHELV3228_RS04950 943716..943946 - 231 WP_115588761.1 type II toxin-antitoxin system YafQ family toxin Toxin
CHELV3228_RS04955 943984..944274 - 291 WP_082199810.1 hypothetical protein Antitoxin
CHELV3228_RS04960 944369..945310 - 942 WP_082199811.1 tyrosine-type recombinase/integrase -
CHELV3228_RS04965 945552..945776 + 225 WP_082199579.1 mobilization protein -
CHELV3228_RS04970 945848..946699 + 852 WP_167562798.1 hypothetical protein -
CHELV3228_RS04975 946832..947686 + 855 WP_082199812.1 HmcD domain-containing protein -
CHELV3228_RS04980 947671..948264 + 594 WP_082199813.1 C39 family peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 943354..1026061 82707


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-74)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 77 a.a.        Molecular weight: 9241.75 Da        Isoelectric Point: 9.4069

>T74735 WP_115588761.1 NZ_CP020478:c943946-943716 [Campylobacter helveticus]
MVRKQNWDIKAIKKCVEDLAILDILPQSYKDHALKGDLKNFRECHIFGDLVIIYKRDDREVNYYRIGRHQDLFKKY

Download         Length: 231 bp

>T74735 NZ_CP020478:c943946-943716 [Campylobacter helveticus]
TTGGTTAGAAAACAAAATTGGGATATTAAGGCAATTAAAAAGTGTGTTGAAGATTTAGCAATATTAGATATTTTACCACA
AAGTTACAAAGACCACGCCCTAAAAGGTGATTTGAAAAATTTTAGAGAGTGCCATATTTTTGGCGATTTAGTTATAATCT
ACAAGAGAGATGATAGGGAAGTTAATTATTACCGCATAGGCAGACACCAAGATTTATTTAAAAAATATTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11295.94 Da        Isoelectric Point: 8.3162

>AT74735 WP_082199810.1 NZ_CP020478:c944274-943984 [Campylobacter helveticus]
MYDYAKYENATPKQLVYALSLAEKRAEKLSLQLKENEEFFKFLQKKLRNSFSTKKIKKEELTKETKAILAKDEPTPYTNF
DRLLEAVDKEIEAENA

Download         Length: 291 bp

>AT74735 NZ_CP020478:c944274-943984 [Campylobacter helveticus]
ATGTATGATTATGCAAAATACGAAAATGCAACTCCAAAACAATTGGTTTATGCACTTTCTTTAGCAGAAAAAAGGGCGGA
AAAACTAAGTTTGCAATTAAAAGAAAATGAAGAGTTTTTTAAATTTTTGCAAAAAAAACTAAGAAATTCTTTTAGCACTA
AAAAAATAAAAAAAGAAGAACTAACAAAGGAAACTAAAGCAATTTTAGCAAAAGACGAACCAACACCTTATACTAACTTT
GATAGACTATTAGAAGCTGTTGATAAAGAGATTGAAGCTGAAAATGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References