Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 154269..154830 Replicon plasmid unnamed4
Accession NZ_CP020444
Organism Paracoccus yeei strain FDAARGOS_252

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag A6J80_RS21655 Protein ID WP_105291675.1
Coordinates 154269..154544 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag A6J80_RS21660 Protein ID WP_080623172.1
Coordinates 154537..154830 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6J80_RS24155 149305..149472 + 168 WP_158595053.1 hypothetical protein -
A6J80_RS23775 149753..150409 - 657 WP_146113114.1 hypothetical protein -
A6J80_RS21640 150409..151128 - 720 WP_080623169.1 hypothetical protein -
A6J80_RS21645 151964..152431 + 468 WP_146113115.1 plasmid mobilization relaxosome protein MobC -
A6J80_RS21650 152424..154223 + 1800 WP_146113116.1 relaxase/mobilization nuclease domain-containing protein -
A6J80_RS21655 154269..154544 - 276 WP_105291675.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A6J80_RS21660 154537..154830 - 294 WP_080623172.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
A6J80_RS21665 154943..156970 - 2028 WP_080623173.1 type IV secretory system conjugative DNA transfer family protein -
A6J80_RS21670 157003..157992 - 990 WP_080623174.1 Flp pilus assembly complex ATPase component TadA -
A6J80_RS21675 157992..159179 - 1188 WP_146113117.1 TrbI/VirB10 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..188526 188526


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-57)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10105.73 Da        Isoelectric Point: 5.6630

>T74689 WP_105291675.1 NZ_CP020444:c154544-154269 [Paracoccus yeei]
VPEIEWREPAVADLMAIVDYISDDNPGAALALMDEIQTKVAQLADHPKRCRPGRVAGTRELIVRPNYLVVYAETAAKVTV
LRVLHAAQMWP

Download         Length: 276 bp

>T74689 NZ_CP020444:c154544-154269 [Paracoccus yeei]
GTGCCTGAAATCGAATGGAGAGAACCGGCGGTTGCGGACCTGATGGCGATTGTCGATTACATCTCGGATGACAATCCCGG
CGCAGCCTTGGCCTTGATGGATGAGATCCAGACCAAGGTCGCGCAACTGGCGGACCATCCGAAACGCTGCCGCCCCGGCA
GGGTGGCAGGCACGCGGGAGCTGATCGTCAGGCCGAACTACCTTGTTGTCTATGCCGAAACTGCGGCTAAGGTCACCGTT
CTGCGTGTTCTTCACGCCGCACAGATGTGGCCGTAG

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10310.88 Da        Isoelectric Point: 9.9916

>AT74689 WP_080623172.1 NZ_CP020444:c154830-154537 [Paracoccus yeei]
MPARTAMLHVRVDSQLKTQATDALAGVGLTLSDAVRILLTRVAAEGGLPAGLTAAPDAYDAWFRAKVQEALSDPRPGKPH
DQVVLEARALIDAKRRA

Download         Length: 294 bp

>AT74689 NZ_CP020444:c154830-154537 [Paracoccus yeei]
ATGCCGGCACGGACCGCGATGCTCCACGTTCGCGTGGACAGCCAGCTCAAGACACAAGCGACAGACGCGCTGGCCGGGGT
GGGATTAACGCTGTCCGATGCCGTACGCATTCTGCTGACCCGGGTTGCCGCTGAAGGCGGGCTGCCAGCGGGCCTCACCG
CGGCGCCAGACGCCTATGACGCCTGGTTTCGGGCCAAGGTGCAGGAAGCGCTGAGCGATCCACGCCCCGGAAAGCCGCAT
GATCAGGTTGTCTTGGAAGCGCGCGCGCTGATCGATGCTAAACGCCGTGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References