Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 92797..93480 Replicon chromosome
Accession NZ_CP020442
Organism Paracoccus yeei strain FDAARGOS_252

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag A6J80_RS02870 Protein ID WP_080620420.1
Coordinates 92797..93225 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag A6J80_RS02875 Protein ID WP_080620421.1
Coordinates 93229..93480 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6J80_RS02845 87854..88489 + 636 WP_146113010.1 hypothetical protein -
A6J80_RS23865 88659..89618 + 960 WP_080620418.1 hypothetical protein -
A6J80_RS02855 89714..91777 + 2064 WP_080620419.1 AAA family ATPase -
A6J80_RS23530 91869..92294 + 426 WP_146113011.1 hypothetical protein -
A6J80_RS02865 92318..92552 - 235 Protein_85 transposase -
A6J80_RS02870 92797..93225 - 429 WP_080620420.1 PIN domain-containing protein Toxin
A6J80_RS02875 93229..93480 - 252 WP_080620421.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
A6J80_RS02880 93534..93727 - 194 Protein_88 DUF3363 domain-containing protein -
A6J80_RS02885 94238..94873 - 636 Protein_89 transposase -
A6J80_RS02890 95127..96296 - 1170 WP_080620422.1 cation:proton antiporter -
A6J80_RS02895 96345..96767 - 423 WP_080620423.1 thioredoxin TrxC -
A6J80_RS02900 96819..97661 - 843 WP_080620424.1 ATP-dependent Clp protease proteolytic subunit -
A6J80_RS02905 97652..98401 - 750 WP_028720449.1 rhomboid family intramembrane serine protease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-65)


Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15284.50 Da        Isoelectric Point: 6.9897

>T74685 WP_080620420.1 NZ_CP020442:c93225-92797 [Paracoccus yeei]
MYLLDTNIVSASAPTRRDTDVLAAWMRVHSDRLYLSAITIAEIEAGIARAVRIGASSKAPALRRWLAALEHFYASRILAF
GIEEARQAGAILDQARAHDPGFEDIAIAATAAAHGLTVLTANERHFAPLGVPYANPLKELPA

Download         Length: 429 bp

>T74685 NZ_CP020442:c93225-92797 [Paracoccus yeei]
TTGTACCTGCTCGATACCAACATCGTTTCGGCCTCCGCGCCGACGAGGCGAGACACCGATGTTCTCGCTGCATGGATGCG
CGTCCACAGCGACCGGCTCTATCTCTCGGCCATCACCATCGCCGAGATCGAGGCCGGCATCGCCCGGGCGGTCAGGATCG
GCGCCAGCAGCAAGGCCCCGGCGCTGCGCCGCTGGCTCGCTGCGCTCGAGCATTTCTACGCCAGCCGGATCCTCGCTTTC
GGCATCGAGGAGGCTCGTCAGGCCGGGGCGATCCTCGACCAGGCGCGTGCCCATGATCCGGGCTTCGAGGACATCGCCAT
CGCGGCGACGGCTGCCGCGCATGGCCTGACGGTGCTGACCGCCAACGAGCGGCATTTCGCGCCGCTCGGCGTGCCCTATG
CAAATCCGTTGAAGGAACTGCCCGCATAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9323.69 Da        Isoelectric Point: 7.0152

>AT74685 WP_080620421.1 NZ_CP020442:c93480-93229 [Paracoccus yeei]
MKELQLRDAKATLSAVVDQAVAGEPTVITRHGRKEAVLLSFEEWQRISRVPDFADLLLAFPGQPEDIPERTRKPARALRD
TSL

Download         Length: 252 bp

>AT74685 NZ_CP020442:c93480-93229 [Paracoccus yeei]
ATGAAGGAACTCCAGCTCAGGGATGCGAAGGCGACGCTCTCCGCCGTGGTCGATCAGGCCGTGGCCGGCGAGCCGACGGT
CATCACCCGGCACGGCCGCAAGGAGGCGGTGCTGCTCTCCTTCGAGGAATGGCAGCGCATCTCGCGAGTTCCGGATTTCG
CCGACCTGCTGCTGGCCTTTCCCGGCCAGCCGGAGGATATCCCCGAACGCACCCGCAAGCCTGCACGCGCGCTGCGGGAT
ACGAGCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References