Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 120401..121072 Replicon plasmid unnamed2
Accession NZ_CP020440
Organism Paracoccus yeei strain FDAARGOS_252

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag A6J80_RS00630 Protein ID WP_080620069.1
Coordinates 120401..120817 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag A6J80_RS00635 Protein ID WP_080620070.1
Coordinates 120818..121072 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6J80_RS00610 116018..117022 + 1005 WP_080620067.1 GTP-binding protein -
A6J80_RS00615 117099..118382 + 1284 WP_105291398.1 lytic murein transglycosylase -
A6J80_RS00620 118402..118797 - 396 WP_028720783.1 acyl-CoA thioesterase -
A6J80_RS00625 118866..120254 - 1389 WP_080620068.1 L-cystine transporter -
A6J80_RS00630 120401..120817 - 417 WP_080620069.1 type II toxin-antitoxin system VapC family toxin Toxin
A6J80_RS00635 120818..121072 - 255 WP_080620070.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
A6J80_RS00640 121186..122493 - 1308 WP_028720780.1 MFS transporter -
A6J80_RS00645 122700..123905 + 1206 WP_105291399.1 ubiquinol oxidase subunit II -
A6J80_RS00650 123918..125930 + 2013 WP_080620071.1 cytochrome o ubiquinol oxidase subunit I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..227674 227674


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-119)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-51)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14892.99 Da        Isoelectric Point: 5.6964

>T74684 WP_080620069.1 NZ_CP020440:c120817-120401 [Paracoccus yeei]
MLILDTNVLSALRRPERSPAVAAWLARQDDTALYLSVVTLGEIERGIVRQESQNPPFARDLRDWLTRTVTLFSDRLLPFS
AAEALLWGQLSARLGHAGADLLIAATALAHDAAVVTGNTADFRPTGCRLVDPFAQGAG

Download         Length: 417 bp

>T74684 NZ_CP020440:c120817-120401 [Paracoccus yeei]
ATGCTGATCCTGGATACCAATGTCCTGTCGGCGCTGCGCCGCCCCGAACGCAGCCCGGCGGTCGCCGCCTGGCTGGCCCG
GCAGGACGACACCGCGCTCTATCTCTCCGTCGTCACCTTGGGCGAGATCGAGCGCGGCATCGTCCGCCAGGAATCGCAGA
ACCCGCCCTTTGCCCGCGACCTGCGCGATTGGCTGACGCGCACCGTCACGCTGTTTTCCGACCGCCTGCTGCCCTTCAGC
GCGGCCGAGGCGCTGCTCTGGGGCCAGCTTTCCGCCCGGCTGGGCCACGCCGGGGCCGACCTGCTGATCGCGGCGACCGC
GCTTGCGCATGACGCGGCCGTGGTCACCGGCAACACCGCCGATTTCCGGCCGACCGGCTGCCGGCTGGTCGATCCCTTCG
CGCAAGGGGCCGGATAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 8996.20 Da        Isoelectric Point: 10.2060

>AT74684 WP_080620070.1 NZ_CP020440:c121072-120818 [Paracoccus yeei]
MWTLQDAKNRFSAVVDAALAGQPQQVTRRGKPAVVVLAAADYARMLAATQENRGSFAAHLLSFPGPDLSPDSGRAWVAPR
DVSF

Download         Length: 255 bp

>AT74684 NZ_CP020440:c121072-120818 [Paracoccus yeei]
ATGTGGACGCTTCAGGATGCCAAGAACCGCTTTTCGGCCGTGGTCGATGCGGCGCTTGCCGGCCAGCCGCAGCAGGTGAC
GCGGCGCGGCAAGCCCGCCGTCGTGGTGCTGGCCGCCGCGGACTACGCCCGGATGCTGGCCGCGACGCAGGAAAACCGCG
GCTCCTTCGCCGCCCACCTCCTCAGCTTTCCGGGCCCCGACCTGAGCCCCGATTCCGGGCGCGCCTGGGTGGCCCCGCGC
GACGTCAGCTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References