Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 59104..59784 Replicon chromosome
Accession NZ_CP020409
Organism Yersinia sp. FDAARGOS_228

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag A6J67_RS00290 Protein ID WP_080607979.1
Coordinates 59104..59424 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag A6J67_RS00295 Protein ID WP_080607980.1
Coordinates 59461..59784 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6J67_RS00275 55928..57766 + 1839 WP_005190373.1 RNA polymerase sigma factor RpoD -
A6J67_RS00285 58156..58989 - 834 WP_080607978.1 DUF4942 domain-containing protein -
A6J67_RS00290 59104..59424 - 321 WP_080607979.1 TA system toxin CbtA family protein Toxin
A6J67_RS00295 59461..59784 - 324 WP_080607980.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
A6J67_RS00300 59797..60270 - 474 WP_080607981.1 DNA repair protein RadC -
A6J67_RS00305 60341..61162 - 822 WP_080607982.1 DUF945 domain-containing protein -
A6J67_RS00310 61282..61734 - 453 WP_080608450.1 hypothetical protein -
A6J67_RS00315 61860..62492 - 633 WP_080607983.1 hypothetical protein -
A6J67_RS00320 62498..63199 - 702 WP_080607984.1 transcriptional regulator -
A6J67_RS00325 63412..64287 - 876 WP_080607985.1 GTPase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(12-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12145.79 Da        Isoelectric Point: 5.9637

>T74634 WP_080607979.1 NZ_CP020409:c59424-59104 [Yersinia sp. FDAARGOS_228]
MHISSVPATVPVSSRLSPVQVWQQLLTYLLEHHYGLTLNDTPFHNDAAIEEHIEAEIKLADAVNFLVERYELVRTDRKGF
TWQEQTPFLTATDILRARRATGLMNT

Download         Length: 321 bp

>T74634 NZ_CP020409:c59424-59104 [Yersinia sp. FDAARGOS_228]
ATGCACATTTCATCTGTACCGGCCACGGTGCCGGTTTCGTCACGCCTGTCGCCCGTACAGGTCTGGCAGCAACTGTTAAC
GTATCTTTTAGAACACCATTATGGCCTCACGCTCAACGACACGCCATTCCATAACGACGCGGCCATTGAGGAGCATATCG
AAGCGGAAATAAAGCTTGCCGATGCGGTTAATTTCCTGGTGGAACGCTATGAACTGGTGCGCACTGATCGTAAGGGTTTC
ACCTGGCAGGAGCAGACACCATTTCTGACTGCTACCGATATTCTCAGAGCAAGACGTGCTACCGGGCTGATGAATACGTA
A

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11945.44 Da        Isoelectric Point: 5.8657

>AT74634 WP_080607980.1 NZ_CP020409:c59784-59461 [Yersinia sp. FDAARGOS_228]
MPLTQSHEWGLQSDITPRFGARLVQEGNRLHYLADRAGLTGSFTPAQLQSLEQAFPLLIVQLENMLHSGELNPHHQHQVA
VQLAEFTSIADTRGSCGYVYISIYPTE

Download         Length: 324 bp

>AT74634 NZ_CP020409:c59784-59461 [Yersinia sp. FDAARGOS_228]
ATGCCATTAACACAATCCCATGAATGGGGGTTGCAAAGCGATATCACCCCACGATTTGGCGCAAGATTGGTTCAGGAAGG
TAACCGGCTGCATTACCTGGCTGACAGGGCCGGTTTGACGGGGAGCTTTACACCAGCGCAGTTACAGAGTTTGGAGCAGG
CTTTCCCGCTGTTGATAGTACAACTGGAAAATATGCTGCATTCCGGTGAGCTAAATCCACATCATCAACATCAGGTGGCA
GTTCAACTTGCTGAATTCACCAGCATAGCGGATACCCGTGGTAGCTGCGGCTACGTTTACATTTCTATTTATCCAACCGA
GTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References