Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 2086176..2086817 Replicon chromosome
Accession NZ_CP020396
Organism Burkholderia vietnamiensis strain FDAARGOS_239

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag A8H33_RS31060 Protein ID WP_045578204.1
Coordinates 2086479..2086817 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag A8H33_RS31055 Protein ID WP_011881499.1
Coordinates 2086176..2086475 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A8H33_RS31030 2081283..2082554 + 1272 WP_014724582.1 Rieske 2Fe-2S domain-containing protein -
A8H33_RS31035 2082572..2083057 + 486 WP_034194948.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
A8H33_RS31040 2083084..2083410 + 327 WP_045578207.1 non-heme iron oxygenase ferredoxin subunit -
A8H33_RS31045 2083400..2084620 + 1221 WP_045578206.1 FAD-dependent oxidoreductase -
A8H33_RS31050 2084809..2086095 + 1287 WP_045578205.1 DUF445 domain-containing protein -
A8H33_RS31055 2086176..2086475 - 300 WP_011881499.1 putative addiction module antidote protein Antitoxin
A8H33_RS31060 2086479..2086817 - 339 WP_045578204.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A8H33_RS31070 2087174..2088814 + 1641 WP_011881501.1 acetolactate synthase large subunit -
A8H33_RS31075 2088843..2090276 + 1434 WP_045578203.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(26-98)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12652.46 Da        Isoelectric Point: 9.4958

>T74595 WP_045578204.1 NZ_CP020396:c2086817-2086479 [Burkholderia vietnamiensis]
MVDISSNVPYSAPTYSIRTTEVFDTWFAGLQDRVARRRIQARIDRLPMGNPGDWKSAGSPVVEMRIDHGPGYRVYYVRRA
TIWVILLCGGDKSTQQADIRAAHAMLGRLDLE

Download         Length: 339 bp

>T74595 NZ_CP020396:c2086817-2086479 [Burkholderia vietnamiensis]
ATGGTTGACATATCGAGTAACGTGCCTTACAGTGCTCCGACGTACAGCATCAGAACGACCGAAGTCTTCGACACATGGTT
CGCCGGTCTGCAGGATCGCGTCGCACGGCGGCGTATCCAGGCCCGCATCGACCGCCTGCCGATGGGCAATCCGGGCGACT
GGAAGTCGGCCGGCTCCCCGGTCGTCGAGATGCGTATCGACCACGGCCCCGGCTATCGCGTCTACTACGTCAGGCGCGCG
ACGATCTGGGTGATCCTGCTCTGCGGCGGCGACAAGTCGACGCAACAGGCAGACATTCGCGCCGCGCACGCAATGCTCGG
GCGGCTCGACCTGGAGTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10548.87 Da        Isoelectric Point: 6.0633

>AT74595 WP_011881499.1 NZ_CP020396:c2086475-2086176 [Burkholderia vietnamiensis]
MDKISTRPWDSAAHLETDDDIADYFDACLQEGGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGAKARA

Download         Length: 300 bp

>AT74595 NZ_CP020396:c2086475-2086176 [Burkholderia vietnamiensis]
ATGGACAAGATCAGCACCCGGCCGTGGGATTCGGCCGCCCACCTCGAAACCGACGACGACATCGCCGACTATTTCGACGC
GTGCCTGCAGGAAGGCGGCGACGACCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCGCGCGCGCGCGGCATGTCGC
AGGTCGCCCGCGACGCCGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGCTTCGGCACC
ATCCTCAAAGTGATCAAGGCGCTCGGCCTGCAACTGCACGGCGCGAAAGCGCGCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References